Zobrazeno 1 - 10
of 447
pro vyhledávání: '"Rob Lavigne"'
Autor:
Luis Ponce Benavente, Jeroen Wagemans, Dennis Hinkel, Alba Aguerri Lajusticia, Rob Lavigne, Andrej Trampuz, Mercedes Gonzalez Moreno
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Staphylococcus aureus´ biofilm-forming ability and rapid resistance development pose a significant challenge to successful treatment, particularly in postoperative complications, emphasizing the need for enhanced therapeutic strategies. Bacteriophag
Externí odkaz:
https://doaj.org/article/afe85921fdc647bf81dc0bd2302c789b
Autor:
Anastasiia Chaban, Leonid Minakhin, Ekaterina Goldobina, Brain Bae, Yue Hao, Sergei Borukhov, Leena Putzeys, Maarten Boon, Florian Kabinger, Rob Lavigne, Kira S. Makarova, Eugene V. Koonin, Satish K. Nair, Shunsuke Tagami, Konstantin Severinov, Maria L. Sokolova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Thermus thermophilus bacteriophage P23-45 encodes a giant 5,002-residue tail tape measure protein (TMP) that defines the length of its extraordinarily long tail. Here, we show that the N-terminal portion of P23-45 TMP is an unusual RNA polym
Externí odkaz:
https://doaj.org/article/df2a07d49e874c7f8abbaf09ef7dc600
Autor:
Ana C. Brandão, Leena Putzeys, Diana P. Pires, Marleen Voet, Jan Paeshuyse, Joana Azeredo, Rob Lavigne
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 235-247 (2023)
Phage therapy is a promising adjunct therapeutic approach against bacterial multidrug-resistant infections, including Pseudomonas aeruginosa-derived infections. Nevertheless, the current knowledge about the phage-bacteria interaction within a human e
Externí odkaz:
https://doaj.org/article/5edcf73ae3414ba6b893c7e753fef724
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 12, Pp 2367-2386 (2023)
Abstract Bacteriophage‐derived endolysins are a novel class of antimicrobials known to rapidly kill bacteria, including antibiotic‐resistant strains. We here engineered endolysins against the bovine mastitis pathogens Streptococcus uberis, Strept
Externí odkaz:
https://doaj.org/article/e09bbd9210a34e1fa19c3291bc9940f6
Autor:
Kenneth Timmis, John E. Hallsworth, Terry J. McGenity, Rachel Armstrong, María Francisca Colom, Zeynep Ceren Karahan, Max Chavarría, Patricia Bernal, Eric S. Boyd, Juan Luis Ramos, Martin Kaltenpoth, Carla Pruzzo, Gerard Clarke, Purificación López‐Garcia, Michail M. Yakimov, Jessamyn Perlmutter, Chris Greening, Emiley Eloe‐Fadrosh, Willy Verstraete, Olga C. Nunes, Oleg Kotsyurbenko, Pablo Iván Nikel, Paola Scavone, Max M. Häggblom, Rob Lavigne, Frédérique Le Roux, James K. Timmis, Victor Parro, Carmen Michán, José Luis García, Arturo Casadevall, Shelley M. Payne, Joachim Frey, Omry Koren, James I. Prosser, Leo Lahti, Rup Lal, Shailly Anand, Utkarsh Sood, Pierre Offre, Casey C. Bryce, Allen Y. Mswaka, Jörg Jores, Betül Kaçar, Lars Mathias Blank, Nicole Maaßen, Phillip B. Pope, Horia L. Banciu, Judith Armitage, Sang Yup Lee, Fengping Wang, Thulani P. Makhalanyane, Jack A. Gilbert, Thomas K. Wood, Branka Vasiljevic, Mario Soberón, Zulema Udaondo, Fernando Rojo, Jyoti Prakash Tamang, Tatiana Giraud, Jeanne Ropars, Thaddeus Ezeji, Volker Müller, Hirofume Danbara, Beate Averhoff, Angela Sessitsch, Laila Pamela Partida‐Martínez, Wei Huang, Søren Molin, Pilar Junier, Ricardo Amils, Xiao‐Lei Wu, Eliora Ron, Huseyin Erten, Elaine Cristina Pereira deMartinis, Alexander Rapoport, Maarja Öpik, W. Donald R. Pokatong, Courtney Stairs, Mohammad Ali Amoozegar, Jéssica Gil Serna
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 5, Pp n/a-n/a (2024)
Executive summary Microbes are all pervasive in their distribution and influence on the functioning and well‐being of humans, life in general and the planet. Microbially‐based technologies contribute hugely to the supply of important goods and se
Externí odkaz:
https://doaj.org/article/e28069875a95461394a5a0447dd4fdba
Autor:
Mohammad Hashem Yousefi, Jeroen Wagemans, Seyed Shahram Shekarforoush, Marta Vallino, Nadiia Pozhydaieva, Katharina Höfer, Rob Lavigne, Saeid Hosseinzadeh
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract The current threat of multidrug resistant strains necessitates development of alternatives to antibiotics such as bacteriophages. This study describes the isolation and characterization of a novel Salmonella Typhimurium phage ‘Arash’ fro
Externí odkaz:
https://doaj.org/article/549e87b1506a41a5a8a433bb13c4db7c
Autor:
Steven De Soir, Hortence Parée, Nur Hidayatul Nazirah Kamarudin, Jeroen Wagemans, Rob Lavigne, Annabel Braem, Maya Merabishvili, Daniel De Vos, Jean-Paul Pirnay, Françoise Van Bambeke
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT In recent years, bacteriophages (or phages) have reentered the spotlight as alternative or adjuvant therapeutic agents to antibiotics. Their efficacy in more recalcitrant forms of infections like biofilms, frequently encountered in the ortho
Externí odkaz:
https://doaj.org/article/7361fd48e6244f60a5c6b612b7d4bc7a
Autor:
Kaat Schroven, Leena Putzeys, Alison Kerremans, Pieter-Jan Ceyssens, Marta Vallino, Jan Paeshuyse, Farhana Haque, Ahmed Yusuf, Matthias D. Koch, Rob Lavigne
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Two-component systems (TCSs) control a large proportion of virulence factors in Pseudomonas aeruginosa. Yet, investigations on inhibitors of regulatory pathways of TCSs remain scarce, despite their potential in anti-virulence strategies. Thi
Externí odkaz:
https://doaj.org/article/4e46018187c744cc919d7c005e5d76b6
Autor:
Hans Gerstmans, Lisa Duyvejonck, Roberto Vázquez, Ines Staes, Jimmy Borloo, Karim Abdelkader, Jeroen Leroy, Emma Cremelie, Diana Gutiérrez, Héctor Tamés-Caunedo, Patricia Ruas-Madiedo, Ana Rodríguez, Abram Aertsen, Jeroen Lammertyn, Rob Lavigne, Yves Briers
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Therapeutic options to treat bacterial infections caused by Gram-negative pathogens are limited due to the spread of multidrug resistance. Protein engineering of phage-derived lysins can play a key role in the search for new antimicrobial co
Externí odkaz:
https://doaj.org/article/9647b2dd1f1a4099a6ca3d43f85ea00a
Autor:
Eveline-Marie Lammens, Daniel Christophe Volke, Kaat Schroven, Marleen Voet, Alison Kerremans, Rob Lavigne, Hanne Hendrix
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT The development of CRISPR-Cas-based engineering technologies has revolutionized the microbial biotechnology field. Over the years, the Class II Type II CRISPR-Cas9 system has become the gold standard for genome editing in many bacterial host
Externí odkaz:
https://doaj.org/article/e1e19ec83136442aa41296194fb8aaba