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pro vyhledávání: '"Rob J. P. van Tol"'
Autor:
Harald M. H. G. Albers, Anastassis Perrakis, Huib Ovaa, Jens Hausmann, Loes Hendrickx, Rob J. P. van Tol
Publikováno v:
Journal of Medicinal Chemistry
Autotaxin (ATX) is a secreted phosphodiesterase that hydrolyzes the abundant phospholipid lysophosphatidylcholine (LPC) to produce lysophosphatidic acid (LPA). The ATX-LPA signaling axis has been implicated in inflammation, fibrosis, and tumor progre