Výsledky vyhledávání - "Rob G. J. A. Zuiker"

Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers

Autor: Francis M. Dijkstra, Rob G. J. A. Zuiker, Pieter S. Siebenga, Richard A. Leigh‐Pemberton, Lei Sun, Joan D. Manthis, Marieke L. de Kam, Richard Lin, Lisa L. von Moltke, David Rezendes, Joop M. A. van Gerven

Publikováno v: British journal of clinical pharmacology. 88(6)

ALKS 7119 is a novel compound with in vitro affinity highest for the SERT, and for μ receptor, αIn 10 cohorts (n = 10 subjects each), PK, safety and PD (NeuroCart tests, measuring neurophysiologic effects [pupillometry, pharmaco-EEG (pEEG)], visuom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54111141f30b8fbea7e0c8b0dfaf0d90
https://pubmed.ncbi.nlm.nih.gov/35014069

Zobrazit plný text záznamu

Simultaneous measurement of intra-epidermal electric detection thresholds and evoked potentials for observation of nociceptive processing following sleep deprivation

Autor: Boudewijn van den Berg, Hemme J. Hijma, Ingrid Koopmans, Robert J. Doll, Rob G. J. A. Zuiker, Geert Jan Groeneveld, Jan R. Buitenweg

Publikováno v: Experimental Brain Research
Experimental brain research, 240(2), 631-649. Springer
Experimental Brain Research, 240(2), 631-649. SPRINGER

Sleep deprivation has been shown to increase pain intensity and decrease pain thresholds in healthy subjects. In chronic pain patients, sleep impairment often worsens the perceived pain intensity. This increased pain perception is the result of alter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccc09f1fc444e30751a19f70ab4bdfc
https://pubmed.ncbi.nlm.nih.gov/34993590

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání