Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rob Cairns"'
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7033 (2009)
The unique metabolism of tumors was described many years ago by Otto Warburg, who identified tumor cells with increased glycolysis and decreased mitochondrial activity. However, "aerobic glycolysis" generates fewer ATP per glucose molecule than mitoc
Externí odkaz:
https://doaj.org/article/8c0c43a4553c4b0fa183ddb87d295334
Autor:
Marianne Koritzinsky, Michael Milosevic, Marjan Rouzbahman, Ur Metser, David Jaffray, Sara Pakbaz, Douglass Vines, Rob Cairns, Melania Pintilie, Jeffrey Bruce, Naz Chaudary, Ting-Yim Lee, David D'Souza, Neesha Dhani, Jennifer Croke, Tina Shek, Anthony Fyles, Kathy Han
Supplementary Data from A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf14a1d8e035450a00bef2a788559f1
https://doi.org/10.1158/1078-0432.22488981
https://doi.org/10.1158/1078-0432.22488981
Autor:
Marianne Koritzinsky, Michael Milosevic, Marjan Rouzbahman, Ur Metser, David Jaffray, Sara Pakbaz, Douglass Vines, Rob Cairns, Melania Pintilie, Jeffrey Bruce, Naz Chaudary, Ting-Yim Lee, David D'Souza, Neesha Dhani, Jennifer Croke, Tina Shek, Anthony Fyles, Kathy Han
Purpose:Tumor hypoxia is associated with poor response to radiation (RT). We previously discovered a novel mechanism of metformin: enhancing tumor RT response by decreasing tumor hypoxia. We hypothesized that metformin would decrease tumor hypoxia an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277b5ebc89e7e3e2f3b7e21eefa4ad66
https://doi.org/10.1158/1078-0432.c.6532854
https://doi.org/10.1158/1078-0432.c.6532854
Publikováno v:
Cancer Research. 83:SY31-02
The effectiveness of radiation treatment is impacted by spatially defined features of the tumor microenvironment including areas of tumor hypoxia. This is due in part to direct protection against radiation damage by hypoxia, as well as through the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0f076a49b216c1ccb3e7aec1e97aa1
https://doi.org/10.1158/1538-7445.am2023-sy31-02
https://doi.org/10.1158/1538-7445.am2023-sy31-02
Publikováno v:
Open Forum Infectious Diseases. 9
Background Although healthcare worker (HCW) absenteeism due to COVID-19 exposure represents a significant challenge, there are currently no evidence-based criteria for assessing infection risk based on COVID-19 exposure type. We aimed to identify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecea1393aa152b198c7efa9fe8dc3e32
https://doi.org/10.1093/ofid/ofac492.086
https://doi.org/10.1093/ofid/ofac492.086
Autor:
Kathy Han, Anthony Fyles, Tina Shek, Jennifer Croke, Neesha Dhani, David D'Souza, Ting-Yim Lee, Naz Chaudary, Jeffrey Bruce, Melania Pintilie, Rob Cairns, Douglass Vines, Sara Pakbaz, David Jaffray, Ur Metser, Marjan Rouzbahman, Michael Milosevic, Marianne Koritzinsky
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
Purpose: Tumor hypoxia is associated with poor response to radiation (RT). We previously discovered a novel mechanism of metformin: enhancing tumor RT response by decreasing tumor hypoxia. We hypothesized that metformin would decrease tumor hypoxia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a76877b62ee17c55902d4dc004fd75
https://pubmed.ncbi.nlm.nih.gov/36037303
https://pubmed.ncbi.nlm.nih.gov/36037303
Publikováno v:
Acta oto-laryngologica. 125(10)
This is the first report on the measurement of nitric oxide (NO) concentrations in the gas phase in a squamous cell culture. The technique may permit the assessment of NO output under conditions that aim to mimic facets of pathology in relatively ina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95497c90f2edd835fa8281af5d38cf92
https://pubmed.ncbi.nlm.nih.gov/16298791
https://pubmed.ncbi.nlm.nih.gov/16298791
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