Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Rob C. Laister"'
Publikováno v:
HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract CD19‐directed autologous chimeric antigen receptor T cell (CAR‐T) therapy has transformed the management of relapsed/refractory (R/R) large B cell lymphoma (LBCL). Initially approved in the third line and beyond setting, CAR‐T is now s
Externí odkaz:
https://doaj.org/article/fa8dce07de684230b7c7956c73bd0448
Autor:
Maysa Vilbert, Erica C. Koch, April A. N. Rose, Rob C. Laister, Diana Gray, Valentin Sotov, Susanne Penny, Anna Spreafico, Devanand M. Pinto, Marcus O. Butler, Samuel D. Saibil
Publikováno v:
Cancers, Vol 15, Iss 14, p 3708 (2023)
Cutaneous melanoma (CM) patients respond better to immune checkpoint inhibitors (ICI) than mucosal and uveal melanoma patients (MM/UM). Aiming to explore these differences and understand the distinct response to ICI, we evaluated the serum metabolome
Externí odkaz:
https://doaj.org/article/5629b1e6c96b4cab9263690d11aec22a
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 111 (2023)
Exportin-1 (XPO1) is a key player in the nuclear export pathway and is overexpressed in almost all cancers. This is especially relevant for non-Hodgkin lymphoma (NHL), where high XPO1 expression is associated with poor prognosis due to its oncogenic
Externí odkaz:
https://doaj.org/article/d04955b8fee2450a9304782f63cc664e
Autor:
Said Izreig, Alexandra Gariepy, Irem Kaymak, Hannah R. Bridges, Ariel O. Donayo, Gaëlle Bridon, Lisa M. DeCamp, Susan M. Kitchen-Goosen, Daina Avizonis, Ryan D. Sheldon, Rob C. Laister, Mark D. Minden, Nathalie A. Johnson, Thomas F. Duchaine, Marc S. Rudoltz, Sanghee Yoo, Michael N. Pollak, Kelsey S. Williams, Russell G. Jones
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 2, Pp 100014- (2020)
Summary: Cancer cells display metabolic plasticity to survive stresses in the tumor microenvironment. Cellular adaptation to energetic stress is coordinated in part by signaling through the liver kinase B1 (LKB1)-AMP-activated protein kinase (AMPK) p
Externí odkaz:
https://doaj.org/article/d6a25ea75c0340f4b7b742c8469caad8
Autor:
Matthew J. Smith, Elizabeth Ottoni, Noboru Ishiyama, Marilyn Goudreault, André Haman, Claus Meyer, Monika Tucholska, Genevieve Gasmi-Seabrook, Serena Menezes, Rob C. Laister, Mark D. Minden, Rolf Marschalek, Anne-Claude Gingras, Trang Hoang, Mitsuhiko Ikura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Several rearrangements of the MLL gene are associated with acute leukemia, including the fusion of MLL with a RAS effector protein, AF6. Here the authors show that the truncated AF6 can induce AF6-MLL dimerization and drive its oncogenic activity.
Externí odkaz:
https://doaj.org/article/8e1f5d31a64445fb84962ab9b91f057b
Publikováno v:
Precision Cancer Therapies, Volume 1 ‐ Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies. :361-371
Autor:
Laura C. Bahlmann, Chang Xue, Allysia A. Chin, Arianna Skirzynska, Joy Lu, Brigitte Thériault, David Uehling, Yulia Yerofeyeva, Rachel Peters, Kela Liu, Jianan Chen, Anne L. Martel, Martin Yaffe, Rima Al-awar, Rashmi S. Goswami, Jarkko Ylanko, David W. Andrews, John Kuruvilla, Rob C. Laister, Molly S. Shoichet
Publikováno v:
Biomaterials. 297:122121
Autor:
Kate R. Oppegaard, Terri S. Armstrong, Joaquin A. Anguera, Kord M. Kober, Debra Lynch Kelly, Rob C. Laister, Leorey N. Saligan, Ana Patricia Ayala, John Kuruvilla, Mark W. Alm, William H. Byker, Christine Miaskowski, Samantha J. Mayo
Publikováno v:
Critical Reviews in Oncology/Hematology. 180:103822
This scoping review was designed to synthesize the extant literature on associations between subjective and/or objective measures of cancer-related cognitive impairment (CRCI) and blood-based biomarkers in adults with non-central nervous system cance
Autor:
Samantha J Mayo, H. Nakamura, Ryan D. Morin, David Scott, Mary-Margaret Keating, Rashmi S. Goswami, John Kuruvilla, Rob C. Laister, P. Tonseth, Nathalie A. Johnson, M. Elemary, K. Zukotynski, Matthew C. Cheung, Jean-François Larouche, Diego Villa
Publikováno v:
Hematological Oncology. 39
Autor:
Vishal Kukreti, Jessica Weiss, Anca Prica, J. Delabie, Michael Crump, L. Meng, Eyal Lebel, Rob C. Laister, Michael D. Jain, Tony Panzarella, John Kuruvilla, Robert Kridel
Publikováno v:
Hematological Oncology. 39