Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rob, van 't Hof"'
Autor:
Katie J. Lee, Lisa Rambault, George Bou-Gharios, Peter D. Clegg, Riaz Akhtar, Gabriela Czanner, Rob van ‘t Hof, Elizabeth G. Canty-Laird
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/85128b1290fb417e9c2ede93c46f1d2d
Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis
Autor:
Lorenzo Ramos-Mucci, Behzad Javaheri, Rob van ‘t Hof, George Bou-Gharios, Andrew A. Pitsillides, Eithne Comerford, Blandine Poulet
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background Osteoarthritis (OA) is a whole joint disease that affects all joint tissues, with changes in the articular cartilage (AC), subchondral bone and synovium. Pathologies in menisci and ligaments, however, are rarely analysed, although
Externí odkaz:
https://doaj.org/article/ea7a3b7ef99c404ea8387aa427760ec1
Autor:
Claire L. Wood, Karla J. Suchacki, Rob van ’t Hof, Will P. Cawthorn, Scott Dillon, Volker Straub, Sze Choong Wong, Syed F. Ahmed, Colin Farquharson, Annemieke Aartsma-Rus, James Dowling, Maaike van Putten
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 2 (2020)
The muscular dystrophy X-linked (mdx) mouse is commonly used as a mouse model of Duchenne muscular dystrophy (DMD). Its phenotype is, however, mild, and other mouse models have been explored. The mdx:Cmah−/− mouse carries a human-like mutation in
Externí odkaz:
https://doaj.org/article/115a85de5287469e82f3c757ce592baf
Autor:
Claire L Wood, Rob van ‘t Hof, Scott Dillon, Volker Straub, Sze C Wong, S Faisal Ahmed, Colin Farquharson
Publikováno v:
Wood, C L, Van't Hof, R, Dillon, S, Straub, V, Wong, S C, Ahmed, S F & Farquharson, C 2022, ' Combined growth hormone and insulin-like growth factor 1 rescues growth retardation in glucocorticoid-treated mdx mice but does not prevent osteopenia ', Journal of Endocrinology, vol. 253, no. 2, pp. 63-74 . https://doi.org/10.1530/JOE-21-0388
Short stature and osteoporosis are common in Duchenne muscular dystrophy (DMD) and its pathophysiology may include an abnormality of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, which is further exacerbated by long-term glucocorti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77d97c1dcf86a6deeeef8c8569be0c0
https://doi.org/10.1530/joe-21-0388
https://doi.org/10.1530/joe-21-0388
Autor:
Rob van 't Hof, Kendall McCulloch, Kayleigh MacDougal, Carl S. Goodyear, William R. Ferrell, Sarah McGrath, Lynette Dunning, John C. Lockhart, Ana C. Ortiz, Margaret Fegen, Carmen Huesa, Anne Crilly, Gary J. Litherland
Exercise is recommended as a non-pharmacological therapy for osteoarthritis (OA). Clinical studies investigating the impact of exercise on OA have primarily focussed on the assessment of joint pain and mobilisation, where positive outcomes have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e95591aacebde0d7cc039d36fc4ddad8
https://doi.org/10.21203/rs.3.rs-1054109/v1
https://doi.org/10.21203/rs.3.rs-1054109/v1
Autor:
Sally H Cross, Danilo G Macalinao, Lisa McKie, Lorraine Rose, Alison L Kearney, Joe Rainger, Caroline Thaung, Margaret Keighren, Shalini Jadeja, Katrine West, Stephen C Kneeland, Richard S Smith, Gareth R Howell, Fiona Young, Morag Robertson, Rob van T' Hof, Simon W M John, Ian J Jackson
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004359 (2014)
Mutations in the LIM-homeodomain transcription factor LMX1B cause nail-patella syndrome, an autosomal dominant pleiotrophic human disorder in which nail, patella and elbow dysplasia is associated with other skeletal abnormalities and variably nephrop
Externí odkaz:
https://doaj.org/article/dc810faba09b405ebb5e4373b5094526
Autor:
Neil Charles Wallace Mackenzie, Dongxing Zhu, Elspeth M. Milne, Rob van 't Hof, Aline Martin, Darryl Leigh Quarles, José Luis Millán, Colin Farquharson, Vicky Elisabeth MacRae
Publikováno v:
PLoS ONE, Vol 7, Iss 6 (2012)
Externí odkaz:
https://doaj.org/article/88a1ae4daa5d4d6e80a1ac49eac00cca
Autor:
Neil Charles Wallace Mackenzie, Dongxing Zhu, Elspeth M Milne, Rob van 't Hof, Aline Martin, Leigh Darryl Quarles, José Luis Millán, Colin Farquharson, Vicky Elisabeth MacRae
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32177 (2012)
Nucleotide pyrophosphatase phosphodiesterase 1 (NPP1) is required for the conversion of extracellular ATP into inorganic pyrophosphate (PP(i)), a recognised inhibitor of hydroxyapatite (HA) crystal formation. A detailed phenotypic assessment of a mou
Externí odkaz:
https://doaj.org/article/cfca45bf3a314a8abf9e804efd9ccc65