Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Roan, Louw"'
Publikováno v:
Viruses, Vol 16, Iss 2, p 313 (2024)
HIV-exposed, uninfected (HEU) children present with suboptimal growth and a greater susceptibility to infection in early life when compared to HIV-unexposed, uninfected (HUU) children. The reasons for these findings are poorly understood. We used a m
Externí odkaz:
https://doaj.org/article/5d1d20bc2806415b9b7e1906ed679f34
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e15010- (2023)
Various metabolomics studies have reported increased phenylalanine serum concentrations in SARS-CoV-2 positive cases and have correlated increased phenylalanine with COVID-19 severity. In this study, we report similar results based upon metabolomics
Externí odkaz:
https://doaj.org/article/d223ce14dc0047bda1e415d784eecdc8
Autor:
Louise D. V. du Toit, Andrea Prinsloo, Helen C. Steel, Ute Feucht, Roan Louw, Theresa M. Rossouw
Publikováno v:
Viruses, Vol 15, Iss 2, p 279 (2023)
With the global rollout of mother-to-child prevention programs for women living with HIV, vertical transmission has been all but eliminated in many countries. However, the number of children who are exposed in utero to HIV and antiretroviral therapy
Externí odkaz:
https://doaj.org/article/ce6e80aa1fa24907b1ff1181a7e26061
Autor:
Janine Aucamp, Henriette van der Zwan, Zarco Geldenhuys, Aron Abera, Roan Louw, Rencia van der Sluis
Publikováno v:
Research in Veterinary Science. 158:106-116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc04cf028f6e1e1e984cac23dbaf224d
https://doi.org/10.1016/j.rvsc.2023.03.013
https://doi.org/10.1016/j.rvsc.2023.03.013
Publikováno v:
Metabolites, Vol 11, Iss 10, p 658 (2021)
Direct injury of mitochondrial respiratory chain (RC) complex I by Ndufs4 subunit mutations results in complex I deficiency (CID) and a progressive encephalomyopathy, known as Leigh syndrome. While mitochondrial, cytosolic and multi-organelle pathway
Externí odkaz:
https://doaj.org/article/82d0dd382f2948b99be5cad54210d91c
Autor:
Wessel L. du Toit, Ruan Kruger, Lebo F. Gafane-Matemane, Aletta E. Schutte, Roan Louw, Catharina M.C. Mels
Publikováno v:
Nutrition, Metabolism and Cardiovascular Diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3c3cd95966998eff7ff7c87e1a6fc1
https://doi.org/10.1016/j.numecd.2023.05.010
https://doi.org/10.1016/j.numecd.2023.05.010
Publikováno v:
Metabolomics. 19
Introduction A ketogenic diet (KD), which is a high fat, low carbohydrate diet has been shown to inhibit the mammalian target of rapamycin (mTOR) pathway and alter the redox state. Inhibition of the mTOR complex has been associated with the attenuati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50588fd072babfbd797401f92c314726
https://doi.org/10.1007/s11306-023-02006-w
https://doi.org/10.1007/s11306-023-02006-w
Autor:
Wessel L. du Toit, Ruan Kruger, Lebo F. Gafane-Matemane, Aletta E. Schutte, Roan Louw, Catharina M. C. Mels
Publikováno v:
Metabolomics. 19
Introduction Increased exposure to risk factors in the young and healthy contributes to arterial changes, which may be accompanied by an altered metabolism. Objectives To increase our understanding of early metabolic alterations and how they associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d61e519c6ce8237e0b169874d2f42b42
https://doi.org/10.1007/s11306-023-01987-y
https://doi.org/10.1007/s11306-023-01987-y
Autor:
Michél Strauss-Kruger, Tertia van Zyl, Marlien Pieters, Ruan Kruger, Gontse Mokwatsi, Lebo Gafane-Matemane, Hlengiwe Mbongwa, Adriaan Jacobs, Aletta E. Schutte, Roan Louw, Carina Mels
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension.
In Black populations excessive salt intake may exacerbate the genetic predisposition to hypertension and promote the early onset of cardiovascular disease. Ethnic differences in the interaction between sodium intake and the metabolome may play a part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715957001607d8dcd3caaa788d2f42ec
https://pubmed.ncbi.nlm.nih.gov/36229536
https://pubmed.ncbi.nlm.nih.gov/36229536
Autor:
Wessel L. du Toit, Ruan Kruger, Lebo F. Gafane-Matemane, Aletta E. Schutte, Roan Louw, Catharina M.C. Mels
Publikováno v:
Journal of hypertension. 40(8)
Risk factors contributes to a dysregulated metabolism and may ultimately increase the predisposition for cardiovascular disease (CVD) development. To increase our understanding of mechanistic pathways associated with CVD risk, we profiled the urinary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7455f0dfbfe432cf7bcf41edfe1c172b
https://pubmed.ncbi.nlm.nih.gov/35788095
https://pubmed.ncbi.nlm.nih.gov/35788095