Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Roald He"'
Publikováno v:
Thrombosis and Haemostasis. 80:852-858
SummarySince the role of leukocytes found present in thrombi and haemo-static plugs is not clearly understood, we have investigated the interaction between leukocytes and growing thrombi in a human ex vivo model of arterial thrombogenesis. At a wall
Autor:
Roald He, Kjell S. Sakariassen
Publikováno v:
Thrombosis and Haemostasis. 73:126-131
SummaryPlatelet thrombus formation on collagen fibrils is most pronounced at the upstream end of the surface, and it gradually decreases along the axis in parallel with the direction of the blood flow. This phenomenon, known as axial dependent platel
Publikováno v:
Thrombosis and Haemostasis. 71:103-109
SummaryIn the present study we have investigated the effect of a 100 mg single oral dose of a newly developed thromboxane A2 receptor antagonist on collagen-induced thrombogenesis in flowing human non-anticoagulated blood. Blood was drawn directly fr
Autor:
Peter Kierulf, Dickinson Jp, R. M. Barstad, Kieffer G, Skjørten F, Kjell S. Sakariassen, Roald He
Publikováno v:
Thrombosis and Haemostasis. 71:655-662
SummaryThe goal of the present study was to investigate the effect of 7 and 14 days of daily oral administration of 75 mg clopidogrel on collagen-induced thrombogenesis in flowing non-anticoagulated human blood. Blood was drawn directly from an antec
Publikováno v:
Platelets. 10(6)
To gather further information about the effects on blood platelet activation of in vivo exposure to nitric oxide (NO), platelet reactivity was studied in blood from healthy, non-smoking male volunteers before and after 30 min inhalation of 40 ppm NO.
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 17(7)
Abstract We investigated the combined effect of wall shear rate and immobilized collagen on platelet activation in flowing nonanticoagulated human blood. By combining an ex vivo model of thrombogenesis with flow cytometry, we showed that activated pl
Autor:
Kjell S. Sakariassen, Peter Kierulf, Lizette B. Petersen, R. M. Barstad, K T Stokke, Roald He
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 6(5)
We have studied the effect of a daily supplement of 2.4 omega-3 fatty acids (omega 3 FAs) to 16 healthy men on acute collagen-induced thrombus formation in flowing non-anticoagulated blood. The supplement was formulated as Triomar capsules, containin
Autor:
Peter Kierulf, Kjell S. Sakariassen, Åse-Brit Westvik, Marjo Hamers, Henrik Dedichen, Torstein Lyberg, Roald He
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 15(1)
Abstract The objective of the present study was to investigate collagen-induced platelet thrombus formation at arterial blood flow conditions in nonanticoagulated blood from habitual smokers and from nonsmoking patients with severe peripheral atheros
Publikováno v:
Arteriosclerosis and thrombosis : a journal of vascular biology. 14(12)
The precipitating event leading to stroke, myocardial infarction, and/or sudden death may be related to the formation of mural thrombus at the site of a ruptured or superficially damaged stenotic plaque. The fluid dynamic properties at atheroscleroti
Publikováno v:
Europe PubMed Central
Cigarette smoking is a known risk factor for cardiovascular disease in men and women, and it has been suggested that this risk is linked to enhanced formation of platelet thromboxane A2 (TxA2). This led us to investigate the effect of cigarette smoki