Endocan in Acute Leukemia: Current Knowledge and Future Perspectives

Autor: Håkon Reikvam, Kimberley Joanne Hatfield, Øystein Wendelbo, Roald Lindås, Philippe Lassalle, Øystein Bruserud

Publikováno v: Biomolecules, Vol 12, Iss 4, p 492 (2022)

Endocan is a soluble dermatan sulfate proteoglycan expressed by endothelial cells and detected in serum/plasma. Its expression is increased in tumors/tumor vessels in several human malignancies, and high expression (high serum/plasma levels or tumor

Externí odkaz: https://doaj.org/article/3f1cf9c0c8d14957bd9c801183b67a65

Preconditioning Serum Levels of Endothelial Cell-Derived Molecules and the Risk of Posttransplant Complications in Patients Treated with Allogeneic Stem Cell Transplantation

Autor: Roald Lindås, Tor Henrik Andersson Tvedt, Kimberley Joanne Hatfield, Håkon Reikvam, Øystein Bruserud

Publikováno v: Journal of Transplantation, Vol 2014 (2014)

Endothelial cells are involved in the pathogenesis of acute graft-versus-host disease (GVHD) after allogeneic stem cell transplantation. These cells express several molecules that can be detected as biologically active soluble forms; serum levels of

Externí odkaz: https://doaj.org/article/9dff82aec6c942b2963460712740d8b0

Patients with treatment-requiring chronic graft versus host disease after allogeneic stem cell transplantation have altered metabolic profiles due to the disease and immunosuppressive therapy: Potential implication for biomarkers

Autor: Øystein Bruserud, Knut Anders Mosevoll, Håkon Reikvam, Ida Sofie Grønningsæter, Roald Lindås, Kimberley Joanne Hatfield

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2018)

Chronic graft versus host disease (cGVHD) is a common long-term complication after allogeneic hematopoietic stem cell transplantation. The objective of our study was to compare the metabolic profiles for allotransplant recipients and thereby identify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eeb33c677ab7eddf999bcbc27f003b3
https://hdl.handle.net/11250/2726797

Salvage bortezomib–dexamethasone and high-dose melphalan (HDM) and autologous stem cell support (ASCT) in myeloma patients at first relapse after HDM with ASCT. A phase-2 trial

Autor: Niels Abildgaard, Olle Linder, Øyvind Hjertner, Peter Gimsing, Henrik Gregersen, U. H. Mellqvist, Roald Lindås, Stig Lenhoff, Niels Frost Andersen, TW Klausen, N Tøffner Clausen, Tobias Gedde Dahl

Publikováno v: Bone Marrow Transplantation; 50(10), pp 1306-1311 (2015)
Gimsing, P, Hjertner, Ø, Abildgaard, N, Andersen, N F, Dahl, T G, Gregersen, H, Klausen, T W, Mellqvist, U-H, Linder, O, Lindås, R, Tøffner Clausen, N & Lenhoff, S 2015, ' Salvage bortezomib-dexamethasone and high-dose melphalan (HDM) and autologous stem cell support (ASCT) in myeloma patients at first relapse after HDM with ASCT : A phase-2 trial ', Bone Marrow Transplantation, vol. 50, no. 10, pp. 1306-1311 . https://doi.org/10.1038/bmt.2015.125
Bone Marrow Transplantation
The Nordic Myeloma Study Group 2015, ' Salvage bortezomib-dexamethasone and high-dose melphalan (HDM) and autologous stem cell support (ASCT) in myeloma patients at first relapse after HDM with ASCT. A phase-2 trial ', Bone Marrow Transplantation, vol. 50, no. 10, pp. 1306-1311 . https://doi.org/10.1038/bmt.2015.125

Until recently, only retrospective studies had been published on salvage high-dose melphalan (HDM) with autologous stem cell 'transplantation' (ASCT). In a prospective, nonrandomized phase-2 study, we treated 53 bortezomib-naïve patients with bortez

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ac8b86cd54243440824152d6b20220
https://doi.org/10.1038/bmt.2015.125

Serum levels of endothelium-derived endocan are increased in patients with untreated acute myeloid leukemia

Autor: Kimberley Joanne Hatfield, Rafael Alexander Leiva, Øystein Bruserud, Øystein Wendelboe, Roald Lindås, Philippe Lassalle

Publikováno v: Hematology. 16:351-356

Endocan is a soluble proteoglycan expressed only by vascular endothelium and is also found circulating in the bloodstream. Inflammatory cytokines as well as proangiogenic growth factors increase its expression, and increased serum levels are found in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a932738d22b5a6731aa1ce2f5321fe1
https://doi.org/10.1179/102453311x13127324303434