Can K-ras codon 12 mutations be used to distinguish benign bile duct proliferations from metastases in the liver? A molecular analysis of 101 liver lesions from 93 patients

Autor: Rh, Hruban, Pd, Sturm, Rj, Slebos, Re, Wilentz, Ar, Musler, Cj, Yeo, Ta, Sohn, Marie-Louise van Velthuysen, Gj, Offerhaus

Publikováno v: Europe PubMed Central

It can be difficult to distinguish benign bile duct proliferations (BDPs) from well-differentiated metastatic peripancreatic adenocarcinomas on histological grounds alone. Most peripancreatic carcinomas harbor activating point mutations in codon 12 o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2aa08ea8b63c622639b7a79bd9d0792a
http://europepmc.org/abstract/med/9327727

Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial.

Autor: Kim S; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA; Department of Immunology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA. Electronic address: sungjune.kim@moffitt.org., Wuthrick E; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Blakaj D; Department of Radiation Oncology, Ohio State University James Cancer Hospital Solove Research Institute, Columbus, OH, USA., Eroglu Z; Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Verschraegen C; Department of Medical Oncology, Ohio State University James Cancer Hospital Solove Research Institute, Columbus, OH, USA., Thapa R; Department of Biostatistics and Bioinformatics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Mills M; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Dibs K; Department of Radiation Oncology, Ohio State University James Cancer Hospital Solove Research Institute, Columbus, OH, USA., Liveringhouse C; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Russell J; Department of Head and Neck and Cutaneous Oncology, University of Utah Huntsman Cancer Institute, Salt Lake City, UT, USA., Caudell JJ; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Tarhini A; Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Markowitz J; Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Kendra K; Department of Medical Oncology, Ohio State University James Cancer Hospital Solove Research Institute, Columbus, OH, USA., Wu R; Department of Medical Oncology, Ohio State University James Cancer Hospital Solove Research Institute, Columbus, OH, USA., Chen DT; Department of Biostatistics and Bioinformatics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Berglund A; Department of Biostatistics and Bioinformatics, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Michael L; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Aoki M; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Wang MH; Department of Immunology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Hamaidi I; Department of Immunology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Cheng P; Department of Immunology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., de la Iglesia J; Department of Pathology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Slebos RJ; Department of Head and Neck Endocrine Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Chung CH; Department of Head and Neck Endocrine Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Knepper TC; Department of Precision Medicine, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Moran-Segura CM; Department of Pathology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Nguyen JV; Department of Pathology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Perez BA; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Rose T; Department of Radiology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Harrison L; Department of Radiation Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Messina JL; Department of Pathology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Sondak VK; Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Tsai KY; Department of Pathology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Khushalani NI; Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Brohl AS; Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

Publikováno v: Lancet (London, England) [Lancet] 2022 Sep 24; Vol. 400 (10357), pp. 1008-1019. Date of Electronic Publication: 2022 Sep 12.

Human Papillomavirus Genotype Detection in Oral Gargle Samples Among Men With Newly Diagnosed Oropharyngeal Squamous Cell Carcinoma.

Autor: Martin-Gomez L; Center for Immunization and Infection Research in Cancer, Tampa, Florida., Giuliano AR; Center for Immunization and Infection Research in Cancer, Tampa, Florida., Fulp WJ; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida., Caudell J; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida., Echevarria M; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida., Sirak B; Center for Immunization and Infection Research in Cancer, Tampa, Florida., Abrahamsen M; Center for Immunization and Infection Research in Cancer, Tampa, Florida., Isaacs-Soriano KA; Center for Immunization and Infection Research in Cancer, Tampa, Florida., Hernandez-Prera JC; Department of Pathology, Moffitt Cancer Center, Tampa, Florida., Wenig BM; Department of Pathology, Moffitt Cancer Center, Tampa, Florida., Vorwald K; Department of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, Florida., McMullen CP; Department of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, Florida., Wadsworth JT; Department of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, Florida., Slebos RJ; Center for Immunization and Infection Research in Cancer, Tampa, Florida.; Department of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, Florida., Chung CH; Center for Immunization and Infection Research in Cancer, Tampa, Florida.; Department of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, Florida.

Publikováno v: JAMA otolaryngology-- head & neck surgery [JAMA Otolaryngol Head Neck Surg] 2019 May 01; Vol. 145 (5), pp. 460-466.

The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer.

Autor: Rahman SMJ; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center., Ji X; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center., Zimmerman LJ; Department of Biochemistry., Li M; Department of Biostatistics, and., Harris BK; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center., Hoeksema MD; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center., Trenary IA; Department of Chemical and Biomolecular Engineering, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Zou Y; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center., Qian J; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center., Slebos RJ; Department of Biochemistry., Beane J; Pulmonary Center and Section of Computational Biomedicine, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA., Spira A; Pulmonary Center and Section of Computational Biomedicine, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA., Shyr Y; Department of Biostatistics, and., Eisenberg R; Departments of Pathology, Microbiology, and Immunology., Liebler DC; Department of Biochemistry., Young JD; Department of Chemical and Biomolecular Engineering, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Molecular Physiology and Biophysics, and., Massion PP; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Cancer Early Detection and Prevention Initiative, Vanderbilt Ingram Cancer Center.; Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Veterans Affairs, Tennessee Valley Healthcare System, Nashville, Tennessee, USA.

Publikováno v: JCI insight [JCI Insight] 2016 Nov 17; Vol. 1 (19), pp. e88814. Date of Electronic Publication: 2016 Nov 17.

proBAMsuite, a Bioinformatics Framework for Genome-Based Representation and Analysis of Proteomics Data.

Autor: Wang X; From the ‡Department of Biomedical Informatics., Slebos RJ; §Department of Biochemistry, ¶Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt-Ingram Cancer Center, Nashville, TN 37232., Chambers MC; From the ‡Department of Biomedical Informatics., Tabb DL; From the ‡Department of Biomedical Informatics, §Department of Biochemistry., Liebler DC; From the ‡Department of Biomedical Informatics, §Department of Biochemistry, ¶Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt-Ingram Cancer Center, Nashville, TN 37232., Zhang B; From the ‡Department of Biomedical Informatics, ‖Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232; bing.zhang@vanderbilt.edu.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2016 Mar; Vol. 15 (3), pp. 1164-75. Date of Electronic Publication: 2015 Dec 11.