HostSeq: a Canadian whole genome sequencing and clinical data resource

Autor: S Yoo, E Garg, LT Elliott, RJ Hung, AR Halevy, JD Brooks, SB Bull, F Gagnon, CMT Greenwood, JF Lawless, AD Paterson, L Sun, MH Zawati, J Lerner-Ellis, RJS Abraham, I Birol, G Bourque, J-M Garant, C Gosselin, J Li, J Whitney, B Thiruvahindrapuram, J-A Herbrick, M Lorenti, MS Reuter, OO Adeoye, S Liu, U Allen, FP Bernier, CM Biggs, AM Cheung, J Cowan, M Herridge, DM Maslove, BP Modi, V Mooser, SK Morris, M Ostrowski, RS Parekh, G Pfeffer, O Suchowersky, J Taher, J Upton, RL Warren, RSM Yeung, N Aziz, SE Turvey, BM Knoppers, M Lathrop, SJM Jones, SW Scherer, LJ Strug

Publikováno v: BMC Genomic Data, Vol 24, Iss 1, Pp 1-12 (2023)

Abstract HostSeq was launched in April 2020 as a national initiative to integrate whole genome sequencing data from 10,000 Canadians infected with SARS-CoV-2 with clinical information related to their disease experience. The mandate of HostSeq is to

Externí odkaz: https://doaj.org/article/8dd9330e73634673be15f3808eeffdfb

Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk.

Autor: Gorman BR; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; Booz Allen Hamilton, McLean, VA, USA., Ji SG; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; BridgeBio Pharma, Palo Alto, CA, USA., Francis M; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; Booz Allen Hamilton, McLean, VA, USA., Sendamarai AK; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; Carbone Cancer Center, University of Wisconsin, Madison, WI, USA., Shi Y; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA., Devineni P; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA., Saxena U; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA., Partan E; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA., DeVito AK; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA.; Booz Allen Hamilton, McLean, VA, USA., Byun J; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA., Han Y; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA., Xiao X; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, BC, Canada., Timens W; University Medical Centre Groningen, GRIAC (Groningen Research Institute for Asthma and COPD), University of Groningen, Groningen, Netherlands.; Department of Pathology & Medical Biology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands., Moser J; Office of Research and Development, Department of Veterans Affairs, Washington, DC, USA., Muralidhar S; Office of Research and Development, Department of Veterans Affairs, Washington, DC, USA., Ramoni R; Office of Research and Development, Department of Veterans Affairs, Washington, DC, USA., Hung RJ; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, University of Toronto, Toronto, ON, Canada., McKay JD; Section of Genetics, International Agency for Research on Cancer, World Health Organization, Lyon, France., Bossé Y; Institut universitaire de cardiologie et de pneumologie de Québec, Department of Molecular Medicine, Laval University, Quebec City, QC, Canada., Sun R; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Amos CI; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA.; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA., Pyarajan S; Center for Data and Computational Sciences (C-DACS), VA Boston Healthcare System, Boston, MA, USA. saiju.pyarajan@va.gov.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. saiju.pyarajan@va.gov.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 04; Vol. 15 (1), pp. 8629. Date of Electronic Publication: 2024 Oct 04.

Feedback matters: EEG correlates of empathy involved in the naturalistic communication of emotions.

Autor: Hung RJ; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Low I; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Yeh HC; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Wang PY; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chen YS; Department of Computer Science, National Yang Ming Chiao Tung University, Hsinchu, Taiwan., Chen LF; Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Biomedical Informatics, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Publikováno v: Heliyon [Heliyon] 2024 Sep 27; Vol. 10 (19), pp. e38574. Date of Electronic Publication: 2024 Sep 27 (Print Publication: 2024).

Genome-Wide Analysis to Assess if Heavy Alcohol Consumption Modifies the Association between SNPs and Pancreatic Cancer Risk.

Autor: Ni Z; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland., Kundu P; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., McKean DF; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland., Wheeler W; Information Management Systems, Silver Spring, Maryland., Albanes D; Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Andreotti G; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Antwi SO; Department of Quantitative Health Sciences Research, Mayo Clinic College of Medicine, Jacksonville, Florida., Arslan AA; Department of Obstetrics and Gynecology, New York University School of Medicine, New York, New York.; Department of Population Health, New York University School of Medicine, New York, New York.; Department of Environmental Medicine, New York University School of Medicine, New York, New York., Bamlet WR; Department of Quantitative Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota., Beane-Freeman LE; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Bracci PM; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California., Brennan P; International Agency for Research on Cancer, Lyon, France., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Gallinger S; Lunenfeld-Tanenbaum Research Institute, Sinai Health System and University of Toronto, Toronto, Canada., Gaziano JM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Division of Aging, Brigham and Women's Hospital, Boston, Massachusetts.; Boston VA Healthcare System, Boston, Massachusetts., Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia., Giovannucci EL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Goggins MG; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland., Goodman PJ; SWOG Statistical Center, Fred Hutchinson Cancer Center, Seattle, Washington., Haiman CA; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California., Hassan MM; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas., Holly EA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California., Hung RJ; Lunenfeld-Tanenbaum Research Institute, Sinai Health System and University of Toronto, Toronto, Canada., Katzke V; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, Washington., Kraft P; Trans-Divisional Research Program (TDRP), Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., LeMarchand L; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii., Li D; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas., McCullough ML; Department of Population Science, American Cancer Society, Atlanta, Georgia., Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia., Moore SC; Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Neale RE; Department of Population Health, QIMR Berghofer Medical Research Institute, Queensland, Australia., Oberg AL; Department of Quantitative Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota., Patel AV; Department of Population Science, American Cancer Society, Atlanta, Georgia., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington., Rabe KG; Department of Quantitative Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota., Risch HA; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee., Smith-Byrne K; Cancer Epidemiology Unit, The Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Visvanathan K; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Wactawski-Wende J; Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, New York., White E; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.; Department of Epidemiology, University of Washington, Seattle, Washington., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Yu H; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii., Zeleniuch-Jacquotte A; Department of Population Health, New York University School of Medicine, New York, New York.; Perlmutter Cancer Center, New York University School of Medicine, New York, New York., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee., Zhong J; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Amundadottir LT; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Stolzenberg-Solomon RZ; Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Klein AP; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Publikováno v: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology [Cancer Epidemiol Biomarkers Prev] 2024 Sep 03; Vol. 33 (9), pp. 1229-1239.

Maternal major depression during early pregnancy is associated with impaired child executive functioning at 4.5 years of age.

Autor: Levitan RD; Mood and Anxiety Disorders Program, Centre for Addiction and Mental Health, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Department of Physiology, University of Toronto, Toronto, Ontario, Canada. Electronic address: robert.levitan@camh.ca., Atkinson L; Department of Psychology, Toronto Metropolitan University, Toronto, Ontario, Canada., Knight JA; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Hung RJ; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Wade M; Ontario Institute for Studies in Education, University of Toronto, Toronto, Ontario, Canada., Jenkins JM; Department of Applied Psychology and Human Development, University of Toronto, Ontario, Canada., Bertoni K; Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada., Wong J; Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada., Murphy KE; Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, Ontario, Canada., Lye SJ; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, Ontario, Canada., Matthews SG; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute of Sinai Health, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, Ontario, Canada.

Publikováno v: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2024 Aug; Vol. 231 (2), pp. 246.e1-246.e10. Date of Electronic Publication: 2023 Nov 30.