Lysosomal Potassium Channels.

Autor: Huang P; Collaborative Innovation Center for Biomedicine, School of Clinical Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China., Xu M; Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, Halifax, NS, Canada., Wu Y; Collaborative Innovation Center for Biomedicine, School of Clinical Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China., Rizvi Syeda AK; Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, Halifax, NS, Canada., Dong XP; Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, Halifax, NS, Canada. xpdong@dal.ca.

Publikováno v: Handbook of experimental pharmacology [Handb Exp Pharmacol] 2023; Vol. 278, pp. 127-152.

The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways.

Autor: Xu M; Department of Physiology and Biophysics, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada; Department of Physiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui 230032, China., Almasi S; Department of Biology, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Yang Y; Department of Physiology and Biophysics, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Yan C; Department of Microbiology & Immunology, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Sterea AM; Department of Physiology and Biophysics, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Rizvi Syeda AK; Department of Physiology and Biophysics, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Shen B; Department of Physiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui 230032, China., Richard Derek C; Department of Microbiology & Immunology, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Huang P; College of Basic Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China., Gujar S; Department of Microbiology & Immunology, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Wang J; Department of Microbiology & Immunology, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada., Zong WX; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway NJ08854, USA., Trebak M; Department of Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey PA 17033, USA., El Hiani Y; Department of Physiology and Biophysics, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada. Electronic address: yassine.elhiani@Dal.Ca., Dong XP; Department of Physiology and Biophysics, Dalhousie University, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada; Department of Physiology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui 230032, China. Electronic address: xpdong@dal.ca.

Publikováno v: Cell calcium [Cell Calcium] 2019 May; Vol. 79, pp. 80-88. Date of Electronic Publication: 2019 Mar 02.