Development and Validation of a Novel Risk Stratification Model for Slow-Flow/No-Reflow During Primary Percutaneous Coronary Intervention (the RK-SF/NR Score).

Autor: Kumar R; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan. Electronic address: rajeshnarsoolal@gmail.com., Ammar A; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Saghir T; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Sial JA; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Khan KA; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Shah JA; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Shaikh AH; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Rizvi SNH; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Qamar N; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan., Karim M; National Institute of Cardiovascular Diseases (NICVD), Department of Adult Cardiology, Karachi, Pakistan.

Publikováno v: The American journal of cardiology [Am J Cardiol] 2022 May 15; Vol. 171, pp. 32-39. Date of Electronic Publication: 2022 Mar 16.

Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.

Autor: Harshfield EL; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. eh457@medschl.cam.ac.uk.; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0QQ, UK. eh457@medschl.cam.ac.uk., Fauman EB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, 02139, USA., Stacey D; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Ziemek D; Inflammation and Immunology, Pfizer Worldwide Research, Development and Medical, 10785, Berlin, Germany., Ong RMY; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Rasheed A; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Sattar T; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Zameer-Ul-Asar; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Saleem I; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Hina Z; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Ishtiaq U; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Qamar N; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Mallick NH; Punjab Institute of Cardiology, Lahore, 42000, Pakistan., Yaqub Z; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Saghir T; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Rizvi SNH; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Memon A; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Ishaq M; Karachi Institute of Heart Diseases, Karachi, 75950, Pakistan., Rasheed SZ; Karachi Institute of Heart Diseases, Karachi, 75950, Pakistan., Memon FU; Red Crescent Institute of Cardiology, Hyderabad, 71500, Pakistan., Jalal A; Faisalabad Institute of Cardiology, Faisalabad, 38000, Pakistan., Abbas S; Faisalabad Institute of Cardiology, Faisalabad, 38000, Pakistan., Frossard P; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Saleheen D; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.; Department of Biostatistics & Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA., Wood AM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, CB2 1GA, UK. julian.griffin@imperial.ac.uk.; Section of Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, SW7 2AZ, UK. julian.griffin@imperial.ac.uk., Koulman A; Core Metabolomics and Lipidomics Laboratory, National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK. ak675@medschl.cam.ac.uk.

Publikováno v: BMC medicine [BMC Med] 2021 Sep 10; Vol. 19 (1), pp. 232. Date of Electronic Publication: 2021 Sep 10.

Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with single vs multivessel disease.

Autor: Muhammad AS; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan. dratifsher89@gmail.com., Ashraf T; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Mir A; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Alishan S; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Farooq F; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Ammar A; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Karim M; Department of Clinical Research, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Rizvi SNH; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Saghir T; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Sial JA; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan., Khan NU; Department of Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi 75510, Pakistan.

Publikováno v: World journal of cardiology [World J Cardiol] 2020 Apr 26; Vol. 12 (4), pp. 136-143.

An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.

Autor: Harshfield EL; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care , University of Cambridge , Cambridge CB1 8RN , U.K.; Stroke Research Group, Department of Clinical Neurosciences , University of Cambridge , Cambridge CB2 0QQ , U.K., Koulman A; Core Metabolomics and Lipidomics Laboratory , National Institute for Health Research Cambridge Biomedical Research Centre , Cambridge CB2 0QQ , U.K., Ziemek D; Inflammation and Immunology, Pfizer Worldwide Research & Development , 10785 Berlin , Germany., Marney L; College of Science and Engineering , Seattle University , Seattle , Washington 98122 , United States., Fauman EB; Genomic Sciences and Technologies, Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States., Paul DS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care , University of Cambridge , Cambridge CB1 8RN , U.K., Stacey D; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care , University of Cambridge , Cambridge CB1 8RN , U.K., Rasheed A; Center for Non-Communicable Diseases , Karachi 75300 , Pakistan., Lee JJ; Department of Medicine , Mayo Hospital , Lahore 54000 , Pakistan., Shah N; Center for Non-Communicable Diseases , Karachi 75300 , Pakistan.; Department of Pharmacy , COMSATS Institute of Information Technology , Abbottabad 22060 , Pakistan., Jabeen S; Center for Non-Communicable Diseases , Karachi 75300 , Pakistan., Imran A; Center for Non-Communicable Diseases , Karachi 75300 , Pakistan., Abbas S; Department of Cardiology , Faisalabad Institute of Cardiology , Faisalabad 38000 , Pakistan., Hina Z; Department of Cardiology , Faisalabad Institute of Cardiology , Faisalabad 38000 , Pakistan., Qamar N; National Institute of Cardiovascular Disorders , Karachi 75510 , Pakistan., Mallick NH; Punjab Institute of Cardiology , Lahore 42000 , Pakistan., Yaqoob Z; Karachi Institute of Heart Diseases , Karachi 75950 , Pakistan., Saghir T; National Institute of Cardiovascular Disorders , Karachi 75510 , Pakistan., Rizvi SNH; National Institute of Cardiovascular Disorders , Karachi 75510 , Pakistan., Memon A; National Institute of Cardiovascular Disorders , Karachi 75510 , Pakistan., Rasheed SZ; Karachi Institute of Heart Diseases , Karachi 75950 , Pakistan., Memon FU; Red Crescent Institute of Cardiology , Hyderabad 71500 , Pakistan., Qureshi IH; Department of Medicine , Mayo Hospital , Lahore 54000 , Pakistan., Ishaq M; Karachi Institute of Heart Diseases , Karachi 75950 , Pakistan., Frossard P; Center for Non-Communicable Diseases , Karachi 75300 , Pakistan., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care , University of Cambridge , Cambridge CB1 8RN , U.K., Saleheen D; Center for Non-Communicable Diseases , Karachi 75300 , Pakistan.; Department of Biostatistics and Epidemiology , University of Pennsylvania , Philadelphia , Pennsylvania 19104 , United States., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care , University of Cambridge , Cambridge CB1 8RN , U.K., Wood AM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care , University of Cambridge , Cambridge CB1 8RN , U.K., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre , University of Cambridge , Cambridge CB2 1GA , U.K.

Publikováno v: Journal of proteome research [J Proteome Res] 2019 Jun 07; Vol. 18 (6), pp. 2397-2410. Date of Electronic Publication: 2019 Apr 26.

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.

Autor: Zhao W; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rasheed A; Center for Non-Communicable Diseases, Karachi, Pakistan., Tikkanen E; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Lee JJ; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Orho-Melander M; Department of Clinical Sciences, Lund University, Malmö, Sweden., Damrauer S; Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Small A; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Asma S; Department of Mathematics and Statistics, McMaster University, Hamilton, Ontario, Canada., Imamura M; Laboratory for Endocrinology, Metabolism, and Kidney Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.; Division of Clinical Laboratory and Blood Transfusion, University of the Ryukyus Hospital, Nishihara, Japan., Yamauch T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital NHS Trust, Southall, UK.; Imperial College Healthcare NHS Trust, London, UK., Chen P; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Sapkota BR; Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Shah N; Center for Non-Communicable Diseases, Karachi, Pakistan.; Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan., Jabeen S; Center for Non-Communicable Diseases, Karachi, Pakistan., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Lu Y; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital NHS Trust, Southall, UK., Imran A; Center for Non-Communicable Diseases, Karachi, Pakistan., Abbas S; Faisalabad Institute of Cardiology, Faisalabad, Pakistan., Majeed F; Center for Non-Communicable Diseases, Karachi, Pakistan., Trindade K; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Qamar N; National Institute of Cardiovascular Disorders, Karachi, Pakistan., Mallick NH; Punjab Institute of Cardiology, Lahore, Pakistan., Yaqoob Z; National Institute of Cardiovascular Disorders, Karachi, Pakistan., Saghir T; National Institute of Cardiovascular Disorders, Karachi, Pakistan., Rizvi SNH; National Institute of Cardiovascular Disorders, Karachi, Pakistan., Memon A; National Institute of Cardiovascular Disorders, Karachi, Pakistan., Rasheed SZ; Karachi Institute of Heart Diseases, Karachi, Pakistan., Memon FU; Red Crescent Institute of Cardiology, Hyderabad, Pakistan., Mehmood K; Department of Medicine, Civil Hospital, Karachi, Pakistan., Ahmed N; Department of Neurology, Liaquat National Hospital, Karachi, Pakistan., Qureshi IH; Department of Medicine, Mayo Hospital and King Edward Medical University, Lahore, Pakistan., Tanveer-Us-Salam; Department of Neurology, Lahore General Hospital, Lahore, Pakistan., Iqbal W; Department of Neurology, Lahore General Hospital, Lahore, Pakistan., Malik U; Department of Medicine, Mayo Hospital and King Edward Medical University, Lahore, Pakistan., Mehra N; All-India Institute of Medical Sciences, New Delhi, India., Kuo JZ; Clinical and Medical Affairs, CardioDx, Inc., Redwood City, California, USA.; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Sheu WH; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan, and Chung Shan Medical University, Taichung, Taiwan., Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Hsiung CA; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan., Juang JJ; Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Hung YJ; Division of Endocrinology and Metabolism, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Quertermous T; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Lee IT; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan, and Chung Shan Medical University, Taichung, Taiwan., Hsu CC; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Ralhan S; Hero DMC Heart Institute Ludhiana, Punjab, India., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, A*STAR, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; National University of Singapore Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore., Wang TD; Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Alam DS; International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Epstein S; MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC, USA., Nielsen SF; Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tybjaerg-Hansen A; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Benn M; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Frikke-Schmidt R; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Kamstrup PR; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands., Sattar N; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Smit R; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Chung RH; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan., Liang KW; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan., Anand S; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada., Sanghera DK; Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.; Oklahoma Center for Neuroscience, Oklahoma City, Oklahoma, USA., Ripatti S; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Kooner JS; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Tai ES; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Chen YI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA., Frossard P; Center for Non-Communicable Diseases, Karachi, Pakistan., Maeda S; Laboratory for Endocrinology, Metabolism, and Kidney Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Advanced Genomic and Laboratory Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.; Division of Clinical Laboratory and Blood Transfusion, University of the Ryukyus Hospital, Nishihara, Japan., Kadowaki T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan., Reilly M; Cardiology Division, Department of Medicine and the Irving Institute for Clinical and Translational Research, Columbia University, New York, New York, USA., Pare G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Melander O; Department of Clinical Sciences, Lund University, Malmö, Sweden.; Hypertension and Cardiovascular Disease, Department of Clinical Sciences, Lund University, Malmö, Sweden., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Rader DJ; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Voight BF; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Saleheen D; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan.

Publikováno v: Nature genetics [Nat Genet] 2017 Oct; Vol. 49 (10), pp. 1450-1457. Date of Electronic Publication: 2017 Sep 04.