Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin.

Autor: Xu S; Department of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.; Program in Immunology, Tufts Graduate School of Biomedical Sciences , Boston, Massachusetts, USA., Mo D; Department of Biological Sciences, San Jose State University , San Jose, California, USA.; Department of Microbiology and Environmental Toxicology, University of California , Santa Cruz, California, USA., Rizvi FZ; Department of Biological Sciences, San Jose State University , San Jose, California, USA.; Department of Microbiology and Environmental Toxicology, University of California , Santa Cruz, California, USA., Rosa JP; Department of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.; University of Puerto Rico , Cayey, USA., Ruiz J; Department of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.; Francisco de Vitoria University , Madrid, Spain., Tan S; Department of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA., Tweten RK; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center , Oklahoma, Oklahoma, USA., Leong JM; Department of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.; Stuart B. Levy Center for Integrated Management of Antimicrobial Resistance at Tufts (Levy CIMAR) , Boston, Massachusetts, USA., Adams W; Department of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.; Department of Biological Sciences, San Jose State University , San Jose, California, USA.

Publikováno v: Infection and immunity [Infect Immun] 2023 Sep 14; Vol. 91 (9), pp. e0021323. Date of Electronic Publication: 2023 Aug 21.