Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Riyun Yang"'
Autor:
Jingying Pan, Qi Yao, Yankai Wang, Suyan Chang, Chenlong Li, Yongjiang Wu, Jianhong Shen, Riyun Yang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Alzheimer’s disease (AD) is a debilitating progressively neurodegenerative disease. The best-characterized hallmark of AD, which is marked by behavioral alterations and cognitive deficits, is the aggregation of deposition of amyloid-beta (Aβ) and
Externí odkaz:
https://doaj.org/article/d88b3f114db34bb7bb86484b513114e3
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Huntingtin-associated protein 1 (HAP1) was the first protein discovered to interact with huntingtin. Besides brain, HAP1 is also expressed in the spinal cord, dorsal root ganglion, endocrine, and digestive systems. HAP1 has diverse functions involvin
Externí odkaz:
https://doaj.org/article/8f2d083b07d041de9acfcd57a4f9ed54
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Pain is common and frequent in many neurodegenerative diseases, although it has not received much attention. In Huntington’s disease (HD), pain is often ignored and under-researched because attention is more focused on motor and cognitive decline t
Externí odkaz:
https://doaj.org/article/d7eb3ef41f5949d9b149c63f5eeb260a
Publikováno v:
Balkan Medical Journal, Vol 39, Iss 1, Pp 39-47 (2022)
Background: Nck1 is an important molecule that participates in many cellular processes, including neurite outgrowth, synaptic plasticity, and apoptosis. However, the expression and function of Nck1 in the spinal cord and spinal cord injury remain unk
Externí odkaz:
https://doaj.org/article/fc92fdc9f64f4e2c81e12f427f093206
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes, oligodendrocytes, microglia and other non-neuronal cells become dysf
Externí odkaz:
https://doaj.org/article/6daae1a1066644b89adb1059e0878238
Autor:
JingYing, Pan, YaYu, Zhao, Rui, Sang, RiYun, Yang, JingYin, Bao, YongJiang, Wu, Ying, Fei, Jian, Wu, Gang, Chen
Publikováno v:
Pain.
Although pain dysfunction is increasingly observed in Huntington disease (HD), the underlying mechanisms still unknown. As a crucial huntington-associated protein, HAP1 is enriched in normal spinal dorsal horn and dorsal root ganglia (DRG) where are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b3ce6f9b6aeb3e3fc22087514fe337f
https://pubmed.ncbi.nlm.nih.gov/36508175
https://pubmed.ncbi.nlm.nih.gov/36508175
Autor:
Hao Chen, Renfang Mao, Yihui Fan, Xiu Gong, Fengbo Zhao, Jinhuan Wei, Aifen Liu, Shiyin Chen, Riyun Yang, Bin Chen
Publikováno v:
Tumori. 108(1)
Background: Hypoxia is a hallmark of solid cancers, including hepatocellular carcinoma (HCC). There is scarce information about how hypoxia avoids immunologic stress and maintains a cancer-promoting microenvironment. Methods: The Cancer Genome Atlas,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecae2684163a63833192d0232e2cf6a
https://pubmed.ncbi.nlm.nih.gov/34165025
https://pubmed.ncbi.nlm.nih.gov/34165025
Autor:
Renfang Mao, Yihui Fan, Yuanpei Xu, Chenlu Wang, Riyun Yang, Yongming Wang, Jianbo Shen, Yue Ming, Yuanyuan Wu, Shouyan Wang, Xia Chen
Publikováno v:
Gene. 669:35-41
Regnase-1 is not only a key component in maintaining intracellular homeostasis but also a critical negative regulator in preventing autoimmune diseases and cancer development. To keep homeostatic state, Regnase-1 has to be maintained at a desired lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c392d58847f4e1925001df4bdb2edd72
https://doi.org/10.1016/j.gene.2018.05.052
https://doi.org/10.1016/j.gene.2018.05.052
Autor:
Renfang Mao, Yuanpei Xu, Yue Ming, Yihui Fan, Riyun Yang, Xia Chen, Hao Chen, Yuanyuan Wu, Min Yao
Publikováno v:
Cell biochemistry and function. 37(3)
Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma, and up to 30% DLBCL patients eventually died by using first-line chemotherapy regimens. Currently, Bruton tyrosine kinase (BTK) inhibitor (ibrutinib) is one of the most promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261d9e94a0b23a3e24725167239f0f70
https://pubmed.ncbi.nlm.nih.gov/30907011
https://pubmed.ncbi.nlm.nih.gov/30907011
Autor:
Yingcheng Wu, Yuyan Chen, Yihui Fan, Riyun Yang, Erhao Zhang, Cuihua Lu, Lishuai Qu, Hao Chen, Yuanyuan Wu, Zhou Wang, Renfang Mao
Publikováno v:
Aging (Albany NY)
Human papillomavirus (HPV) positive head and neck cancer displayed specific transcription landscape but the underlying molecular mechanisms are not fully determined. Here, we interestingly found that HPV infection could globally elongate the 3'-untra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6142fc1cd2e25993a4fc9d98d9f019bd
https://pubmed.ncbi.nlm.nih.gov/31039132
https://pubmed.ncbi.nlm.nih.gov/31039132