Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Riyad El Khoury"'
Autor:
Paule Bénit, Judith Goncalves, Riyad El Khoury, Malgorzata Rak, Judith Favier, Anne-Paule Gimenez-Roqueplo, Pierre Rustin
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1788 (2022)
Research focused on succinate dehydrogenase (SDH) and its substrate, succinate, culminated in the 1950s accompanying the rapid development of research dedicated to bioenergetics and intermediary metabolism. This allowed researchers to uncover the imp
Externí odkaz:
https://doaj.org/article/fb1bca52e480479c8de00d10783417b0
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
FARS2, a nuclear gene, encodes the mitochondrial phenylalanyl-tRNA synthetase (mtPheRS). Previous reports have described two distinct phenotypes linked to FARS2 gene mutation: an early onset epileptic encephalopathy and spastic paraplegia. This repor
Externí odkaz:
https://doaj.org/article/baefd1b80de2451697e570af8f61722c
Autor:
Muhammad Ali Haidar, Zaynab Shakkour, Chloe Barsa, Maha Tabet, Sarin Mekhjian, Hala Darwish, Mona Goli, Deborah Shear, Jignesh D. Pandya, Yehia Mechref, Riyad El Khoury, Kevin Wang, Firas Kobeissy
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 250 (2022)
Traumatic brain injury (TBI) is a heterogeneous disease in its origin, neuropathology, and prognosis, with no FDA-approved treatments. The pathology of TBI is complicated and not sufficiently understood, which is the reason why more than 30 clinical
Externí odkaz:
https://doaj.org/article/b030213d08724bcf8a971b9fd9897c7c
Autor:
Dominique Chrétien, Paule Bénit, Christine Leroy, Riyad El-Khoury, Sunyou Park, Jung Yeol Lee, Young-Tae Chang, Guy Lenaers, Pierre Rustin, Malgorzata Rak
Publikováno v:
Chemosensors, Vol 8, Iss 4, p 124 (2020)
Mitochondria are the source of internal heat which influences all cellular processes. Hence, monitoring mitochondrial temperature provides a unique insight into cell physiology. Using a thermosensitive fluorescent probe MitoThermo Yellow (MTY), we ha
Externí odkaz:
https://doaj.org/article/caa9f2c598fc497b9e3fb1c4be9c9f46
Autor:
Helene Ismail, Zaynab Shakkour, Maha Tabet, Samar Abdelhady, Abir Kobaisi, Reem Abedi, Leila Nasrallah, Gianfranco Pintus, Yusra Al-Dhaheri, Stefania Mondello, Riyad El-Khoury, Ali H. Eid, Firas Kobeissy, Johnny Salameh
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 943 (2020)
Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic and ionic imbalance, which eventually leads to excessive productio
Externí odkaz:
https://doaj.org/article/d8918cc07efb437284ccabcebc0c8347
Autor:
Dominique Chrétien, Paule Bénit, Hyung-Ho Ha, Susanne Keipert, Riyad El-Khoury, Young-Tae Chang, Martin Jastroch, Howard T Jacobs, Pierre Rustin, Malgorzata Rak
Publikováno v:
PLoS Biology, Vol 16, Iss 1, p e2003992 (2018)
In endothermic species, heat released as a product of metabolism ensures stable internal temperature throughout the organism, despite varying environmental conditions. Mitochondria are major actors in this thermogenic process. Part of the energy rele
Externí odkaz:
https://doaj.org/article/189b7e0db0d641c4ba0de7c0b9523512
Autor:
Dolly Prabhu, Amy C. Goldstein, Riyad El-Khoury, Malgorzata Rak, Lia Edmunds, Pierre Rustin, Jerry Vockley, Manuel Schiff
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 3, Iss C, Pp 43-46 (2015)
Adenine nucleotide translocase 2 (ANT2) transports glycolytic ATP across the inner mitochondrial membrane. Patients with ANT2 deletion were recently reported. We aimed at characterizing mitochondrial functions in ANT2-defective fibroblasts. In spite
Externí odkaz:
https://doaj.org/article/1e782fc85cea4e24be2eff9c40a7592a
Autor:
Mohammad Amine Reslan, Maya Jammoul, Leila Nasrallah, Maha Tabet, Marya El-Kurdi, Sarin Mekhjian, Judith Nwaiwu, Mona Goli, Yehia Mechref, Kevin K Wang, Firas Kobeissy, Riyad El Khoury
Mild traumatic brain injury (mTBI) or concussion accounts for the bulk of all head injuries and represents a major health concern. Although an mTBI event may not manifest in neurobehavioral impairment, repeated injuries, known as repeated mTBI (rmTBI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73907b45b67f775d13bbd78fddc40b1
https://doi.org/10.20944/preprints202207.0316.v1
https://doi.org/10.20944/preprints202207.0316.v1
Publikováno v:
Chemotherapy. 66:179-191
Background: Tumorigenesis is associated with deregulation of nutritional requirements, intermediary metabolites production, and microenvironment interactions. Unlike their normal cell counterparts, tumor cells rely on aerobic glycolysis, through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89afad084a54ed2ca91c8db7df57f42d
https://doi.org/10.1159/000519784
https://doi.org/10.1159/000519784
Cyanide resistant respiration and the alternative oxidase pathway : A journey from plants to mammals
In a large number of organisms covering all phyla, the mitochondrial respiratory chain harbors, in addition to the conventional elements, auxiliary proteins that confer adaptive metabolic plasticity. The alternative oxidase (AOX) represents one of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a4e38d4cdd7e2c1238329c1010cc6c
https://trepo.tuni.fi/handle/10024/140813
https://trepo.tuni.fi/handle/10024/140813