Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Riya Muckom"'
Autor:
Douglas S. Clark, Joshua A. Zimmermann, Natalie Suhy, Rocío Guadalupe Sampayo, Riya Muckom, Yibo Xu, Maroof M. Adil, Aurelie Tran, Xiaoping Bao, David V. Schaffer
Publikováno v:
Stem Cells. 37:1556-1566
Transcription factors (TFs) are potent proteins that control gene expression and can thereby drive cell fate decisions. Fluorescent reporters have been broadly knocked into endogenous TF loci to investigate the biological roles of these factors; howe
Autor:
Douglas S. Clark, Brian C. Perea, Riya Muckom, Jonathan S. Dordick, David V. Schaffer, Megan Gentes, Abirami Murugappan, Eric Tran, Chun Yang, Sean McFarland
Publikováno v:
Biotechnology and Bioengineering. 116:193-205
Advancing our knowledge of how neural stem cell (NSC) behavior in the adult hippocampus is regulated has implications for elucidating basic mechanisms of learning and memory as well as for neurodegenerative disease therapy. To date, numerous biochemi
Autor:
Caroline Sugnaux, Riya Muckom, Barbara L. Ekerdt, Anusuya Ramasubramanian, Kevin E. Healy, David V. Schaffer, Douglas S. Clark, Christina M. Fuentes
Publikováno v:
ACS biomaterials scienceengineering. 7(4)
Human pluripotent stem cells harbor an unlimited capacity to generate therapeutically relevant cells for applications in regenerative medicine. However, to utilize these cells in the clinic, scalable culture systems that activate defined receptors an
Publikováno v:
Adv Funct Mater
The progressively deeper understanding of mechanisms underlying stem cell fate decisions has enabled parallel advances in basic biology-such as the generation of organoid models that can further one's basic understanding of human development and dise
Autor:
Riya Muckom, Xiaoping Bao, Jonathan S. Dordick, Evelyn Chen, Eric Tran, David V. Schaffer, Douglas S. Clark, Abirami Murugappan
Publikováno v:
Science Advances
A high-throughput 3D hPSC differentiation screening strategy reveals basic and translational insight for CNS cell therapies.
The emergence of several cell therapy candidates in the clinic is an encouraging sign for human diseases/disorders that
The emergence of several cell therapy candidates in the clinic is an encouraging sign for human diseases/disorders that
Publikováno v:
Chemical communications (Cambridge, England). 55(6)
We demonstrate the synthesis of protein–polymer hybrid hydrogel that can be used as a platform for immobilizing functional proteins. Orthogonal chemistry was employed for cross-linking the hybrid network and conjugating proteins to the gel backbone
Autor:
Riya Muckom, Sean McFarland, Chun Yang, Brian Perea, Megan Gentes, Abirami Murugappan, Eric Tran, Jonathan S. Dordick, Douglas S. Clark, David V. Schaffer
Publikováno v:
Biotechnology and Bioengineering. 116:i-i
Publikováno v:
The Journal of Physical Chemistry B. 117:1810-1818
Molecular dynamics (MD) simulations were used to gain insight on the molecular interactions in a model biological membrane comprised of a bilayer with DPPC (dipalmitoylphosphotidylcholine) and antimicrobial dendritic amphiphile molecules [RCONHC(CH(2