Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Rivka Ravid"'
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 1, Pp 154-164 (2006)
Recent studies have shown that glutamate excitotoxicity may be a component in the etiology of multiple sclerosis (MS). Glutamate transporters determine the levels of extracellular glutamate and are essential to prevent excitotoxicity. We have analyze
Externí odkaz:
https://doaj.org/article/3e63fe66c6b1486da1a625d083114228
Autor:
Iraad F Bronner, Zoltán Bochdanovits, Patrizia Rizzu, Wouter Kamphorst, Rivka Ravid, John C van Swieten, Peter Heutink
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6826 (2009)
BACKGROUND:Understanding the aetiologies of neurodegenerative diseases such as Alzheimer's disease (AD), Pick's disease (PiD), Progressive Supranuclear Palsy (PSP) and Frontotemporal dementia (FTD) is often hampered by the considerable clinical and m
Externí odkaz:
https://doaj.org/article/785a746c503549a089e46a6558ad7e19
Autor:
Mitsutoshi Setou, Takao Taki, Wakako Hirano-Sakamaki, Rivka Ravid, Eiji Sugiyama, Takahiro Hayasaka
Publikováno v:
FEBS Letters. 589:3611-3616
Alzheimer's disease (AD) is a progressive dementia associated with loss of memory and cognitive dysfunction. In a previous study, we demonstrated a decrease in b-series gangliosides along with a change in ganglioside molecular species in the hippocam
Autor:
Nam Hyun Park, Kyunghee Byun, Rivka Ravid, Young Mok Park, Myoung-Goo Kang, Bonghee Lee, Jae Ho Kim, Harry W.M. Steinbusch, Helmut Heinsen
Publikováno v:
Biochimica et Biophysica Acta-Proteins and Proteomics, 1854(7), 788-797. Elsevier Science
The hippocampus is one of the most essential components of the human brain and plays an important role in learning and memory. The hippocampus has drawn great attention from scientists and clinicians due to its clinical importance in diseases such as
Autor:
D.T.R. Coulson, Rivka Ravid, G.B. Irvine, Janet A. Johnston, Simon Brockbank, Nancy Beyer, Joseph F. Quinn, Jan Hellemans
Publikováno v:
Neuroscience. 274:44-52
β-Site amyloid precursor protein cleaving enzyme (BACE1) is the rate-limiting enzyme for production of Aβ peptides, proposed to drive the pathological changes found in Alzheimer's disease (AD). Reticulon 3 (RTN3) is a negative modulator of BACE1 (
Autor:
Jin Young Kim, Kyung Hoon Kwon, Se-Young Kim, Bonghee Lee, Hyoung Joo Lee, Hyun Joo An, Hye Kyeong Min, William S. Hancock, Isidro Ferrer, Chun Kee Chung, Young Ki Paik, Taewook Kang, Rivka Ravid, Gun Wook Park, Jong Shin Yoo, Young Mok Park, In Jung Ji
Publikováno v:
Journal of Proteome Research. 12:97-105
Human chromosome 11 is the third gene-rich chromosome having 1304 protein-coding genes. According to the GeneCards, this chromosome contains 240 genes related to diseases, as it is well known as a disease-rich chromosome. Although there are many prot
Autor:
Rivka Ravid, Mauro Fasano
Publikováno v:
Future Neurology. 7:663-666
Autor:
Jan Hellemans, Shirley Heggarty, Nancy Beyer, D.T.R. Coulson, Janet A. Johnston, G.B. Irvine, Rivka Ravid
Publikováno v:
Journal of Alzheimer's Disease, 29, 863-873. IOS Press
Zinc (Zn 2+ ) is concentrated into pre-synaptic vesicles and co-released with neurotransmitter at some synapses. Zn 2+ can accelerate assembly of the amyloid- peptides (A) and tau protein central to the neuropathological changes found in Alzheimer's
Autor:
Isidro Ferrer, Rivka Ravid
Publikováno v:
FEBS Journal. 279:1167-1176
Exciting developments in basic and clinical neuroscience and recent progress in the field of Parkinson’s disease (PD) are partly a result of the availability of human specimens obtained through brain banks. These banks have optimized the methodolog
Autor:
Rivka Ravid, Simon Brockbank, David T.R. Coulson, Joseph F. Quinn, Jan Hellemans, Janet A. Johnston, Nancy Beyer, G. Brent Irvine
Publikováno v:
Brain Research, 1459, 71-80. Elsevier B.V.
α-Synuclein is a neuronal protein implicated in the etiology of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Whilst increased α-synuclein expression due to gene duplication or triplication can cause familial PD, previous studies of