Genetically modified pigs lacking CD163 PSTII-domain-coding exon 13 are completely resistant to PRRSV infection.

Autor: Salgado B; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, USA., Rivas RB; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, USA., Pinto D; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, USA., Sonstegard TS; Acceligen, Eagan, Minnesota, USA., Carlson DF; Acceligen, Eagan, Minnesota, USA., Martins K; Acceligen, Eagan, Minnesota, USA., Bostrom JR; Acceligen, Eagan, Minnesota, USA., Sinebo Y; Acceligen, Eagan, Minnesota, USA., Rowland RRR; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, USA., Brandariz-Nuñez A; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, USA. Electronic address: brandari@illinois.edu.

Publikováno v: Antiviral research [Antiviral Res] 2024 Jan; Vol. 221, pp. 105793. Date of Electronic Publication: 2024 Jan 04.