Thrombocytopenia and hyperinflammation are induced by extracellular histones circulating in blood.

Autor: Giglio RV; Department of Biomedicine, Neurosciences and Advanced Diagnostics, BiND, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Clinical Laboratory Medicine, University of Palermo, Palermo, Italy., Ligi D; Department of Biomolecular Sciences - DISB, Unit of Clinical Biochemistry, Section of Biochemistry and Biotechnology, University of Urbino Carlo Bo, Urbino, Italy., Della Franca C; Department of Biomolecular Sciences - DISB, Unit of Clinical Biochemistry, Section of Biochemistry and Biotechnology, University of Urbino Carlo Bo, Urbino, Italy., Lo Sasso B; Department of Biomedicine, Neurosciences and Advanced Diagnostics, BiND, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Clinical Laboratory Medicine, University of Palermo, Palermo, Italy., Rivas JZ; Department of Biomolecular Sciences - DISB, Unit of Clinical Biochemistry, Section of Biochemistry and Biotechnology, University of Urbino Carlo Bo, Urbino, Italy., Agnello L; Department of Biomedicine, Neurosciences and Advanced Diagnostics, BiND, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Clinical Laboratory Medicine, University of Palermo, Palermo, Italy., Mannello F; Department of Biomolecular Sciences - DISB, Unit of Clinical Biochemistry, Section of Biochemistry and Biotechnology, University of Urbino Carlo Bo, Urbino, Italy., Ciaccio M; Department of Biomedicine, Neurosciences and Advanced Diagnostics, BiND, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Clinical Laboratory Medicine, University of Palermo, Palermo, Italy.

Publikováno v: Clinical chemistry and laboratory medicine [Clin Chem Lab Med] 2023 Jun 21; Vol. 61 (12), pp. e239-e243. Date of Electronic Publication: 2023 Jun 21 (Print Publication: 2023).