25-Hydroxycholecalciferol Inhibits Cell Growth and Induces Apoptosis in SiHa Cervical Cells via Autocrine Vitamin D Metabolism

Autor: Rivak Punchoo, Greta Dreyer, Tahir S. Pillay

Publikováno v: Biomedicines, Vol 11, Iss 3, p 871 (2023)

Preclinical studies show that the anticancer actions of vitamin D metabolites are mediated by apoptosis, inhibition of cell proliferation and induction of cell cycle arrest. Cervical cancer cells express an autocrine vitamin D metabolising system (VD

Externí odkaz: https://doaj.org/article/3b58bf73b6a948439b4f77a02af36f1b

Variation in the Measurement of Anti-Müllerian Hormone – What Are the Laboratory Issues?

Autor: Rivak Punchoo, Sachin Bhoora

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

Anti-Müllerian Hormone (AMH) is a 140 kDa homodimeric glycoprotein consisting of two identical subunits linked by disulphide bonds and is synthesised by the testes and ovaries. Its clinical applications are prediction of ovarian response and gonadot

Externí odkaz: https://doaj.org/article/c7cc8771f1e3436baf2f0fec33d88473

Laboratory Considerations for Reporting Cycle Threshold Value in COVID-19

Autor: Rivak, Punchoo, Sachin, Bhoora, Avania, Bangalee

Publikováno v: EJIFCC. 33(2)

The Coronavirus Disease 2019 (COVID-19) pandemic is caused by the SARS-CoV-2 RNA virus. Nucleic acid amplification testing (NAAT) is the mainstay to confirm infection. A large number of reverse transcriptase polymerase chain reaction (RT-PCR) assays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41a47cce217d8d599d2e70c506b963f2
https://pubmed.ncbi.nlm.nih.gov/36313906

Evaluation of serological assays for the diagnosis of HIV infection in adults

Autor: Rivak Punchoo, Sachin Bhoora, Avania Bangalee

Publikováno v: South African Family Practice
South African Family Practice; Vol. 63 No. 4 (2021)
South African Family Practice, Vol 63, Iss 1, Pp e1-e5 (2021)

Serological tests based on the enzyme immunoassay (EIA) are the primary tool for the diagnosis of human immunodeficiency virus (HIV) in adults and have rapidly evolved to quicker, affordable and more accurate test formats to detect early HIV infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d683857418a906bda7c22b23d27fa68f
http://europepmc.org/articles/PMC8603111

Applications of machine learning in the chemical pathology laboratory

Autor: Nelishia Pillay, Rivak Punchoo, Sachin Bhoora

Publikováno v: Journal of clinical pathology. 74(7)

Machine learning (ML) is an area of artificial intelligence that provides computer programmes with the capacity to autodidact and learn new skills from experience, without continued human programming. ML algorithms can analyse large data sets quickly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38680c18ca9b71e2b9a24743eb1da011
https://pubmed.ncbi.nlm.nih.gov/34117102