Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Riu Yamashita"'
Autor:
Junyan Du, Shun-Ichiro Kageyama, Riu Yamashita, Kosuke Tanaka, Masayuki Okumura, Atsushi Motegi, Hidehiro Hojo, Masaki Nakamura, Hidenari Hirata, Hironori Sunakawa, Daisuke Kotani, Tomonori Yano, Takashi Kojima, Yamato Hamaya, Motohiro Kojima, Yuka Nakamura, Ayako Suzuki, Yutaka Suzuki, Katsuya Tsuchihara, Tetsuo Akimoto
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Radiotherapy (RT) plus immunotherapy is a promising modality; however, the therapeutic effects are insufficient, and the molecular mechanism requires clarification to further develop combination therapies. Here, we found that the RNA virus s
Externí odkaz:
https://doaj.org/article/2c635e8b72ff436290dfe707e7042414
Autor:
Takafumi Yamauchi, Daisuke Ochi, Naomi Matsukawa, Daisuke Saigusa, Mami Ishikuro, Taku Obara, Yoshiki Tsunemoto, Satsuki Kumatani, Riu Yamashita, Osamu Tanabe, Naoko Minegishi, Seizo Koshiba, Hirohito Metoki, Shinichi Kuriyama, Nobuo Yaegashi, Masayuki Yamamoto, Masao Nagasaki, Satoshi Hiyama, Junichi Sugawara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The elucidation of dynamic metabolomic changes during gestation is particularly important for the development of methods to evaluate pregnancy status or achieve earlier detection of pregnancy-related complications. Some studies have construc
Externí odkaz:
https://doaj.org/article/29fb6bbfa97f4ccc98f20c973417a67f
Autor:
Shunsuke A. Sakai, Masato Aoshima, Kentaro Sawada, Satoshi Horasawa, Ayumu Yoshikawa, Takao Fujisawa, Shigenori Kadowaki, Tadamichi Denda, Nobuhisa Matsuhashi, Hisateru Yasui, Masahiro Goto, Kentaro Yamazaki, Yoshito Komatsu, Ryota Nakanishi, Yoshiaki Nakamura, Hideaki Bando, Yamato Hamaya, Shun-Ichiro Kageyama, Takayuki Yoshino, Katsuya Tsuchihara, Riu Yamashita
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Colorectal cancer (CRC) is one of the most common malignant diseases. Generally, stoma construction is performed following surgery for the resection of the primary tumor in patients with CRC. The association of CRC with the gut microbiota has been wi
Externí odkaz:
https://doaj.org/article/cdf35b72502c4aafb18359cbff9d7ada
Autor:
Kazuaki Harada, Wataru Okamoto, Sachiyo Mimaki, Yasuyuki Kawamoto, Hideaki Bando, Riu Yamashita, Satoshi Yuki, Takayuki Yoshino, Yoshito Komatsu, Atsushi Ohtsu, Naoya Sakamoto, Katsuya Tsuchihara
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background In the era of genome-guided personalized cancer treatment, we must understand chemotherapy-induced genomic changes in tumors. This study evaluated whether adjuvant FOLFOX chemotherapy modifies the mutational profile of recurrent c
Externí odkaz:
https://doaj.org/article/b2caa4ad414143ab8127e5bbbd783121
Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project
Autor:
Sakae Saito, Yuichi Aoki, Toru Tamahara, Maki Goto, Hiroyuki Matsui, Junko Kawashima, Inaho Danjoh, Atsushi Hozawa, Shinichi Kuriyama, Yoichi Suzuki, Nobuo Fuse, Shigeo Kure, Riu Yamashita, Osamu Tanabe, Naoko Minegishi, Kengo Kinoshita, Akito Tsuboi, Ritsuko Shimizu, Masayuki Yamamoto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
A baseline oral microbiome study of the Tohoku Medical Megabank Organization (TMM) was planned to characterize the profile of the oral microbiome in the Japanese population. The study also aimed to clarify risk factors for multifactorial diseases by
Externí odkaz:
https://doaj.org/article/9a24a0a4c6154f059523791ac9c6e3b9
Autor:
Junya Yamagishi, Yukuto Sato, Natsuko Shinozaki, Bin Ye, Akito Tsuboi, Masao Nagasaki, Riu Yamashita
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154389 (2016)
The rapid improvement of next-generation sequencing performance now enables us to analyze huge sample sets with more than ten thousand specimens. However, DNA extraction can still be a limiting step in such metagenomic approaches. In this study, we a
Externí odkaz:
https://doaj.org/article/3691c61499e9489c8c7b87d488f27b71
Autor:
Takahiro Ochiya, Ryo Matoba, Shoji Tajima, Kenta Nakai, Asao Fujiyama, Mika Kimura, Takuro Horii, Atsushi Toyoda, Riu Yamashita, Ryou-u Takahashi, Sumiyo Morita, Izuho Hatada
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 7, Pp 8259-8272 (2012)
DNA methylation of promoters is linked to transcriptional silencing of protein-coding genes, and its alteration plays important roles in cancer formation. For example, hypermethylation of tumor suppressor genes has been seen in some cancers. Alterati
Externí odkaz:
https://doaj.org/article/7cfdae1dfc6f4d9585448f34e0228723
Autor:
Yukuto Sato, Junya Yamagishi, Riu Yamashita, Natsuko Shinozaki, Bin Ye, Takuji Yamada, Masayuki Yamamoto, Masao Nagasaki, Akito Tsuboi
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131607 (2015)
Given the advent of massively parallel DNA sequencing, human microbiome is analyzed comprehensively by metagenomic approaches. However, the inter- and intra-individual variability and stability of the human microbiome remain poorly characterized, par
Externí odkaz:
https://doaj.org/article/d363217312cc4baf9049254a899b6360
Publikováno v:
Japanese Journal of Clinical Oncology. 53:97-104
Background Genome-wide landscape of alternative promoter use remains unknown. We determined expression profiles of promoters in 26 lung adenocarcinoma cell lines using the transcriptional start site-sequencing data and proposed an index ‘canonical
Autor:
Yukari Tanaka, Riu Yamashita, Junko Kawashima, Hiroshi Mori, Ken Kurokawa, Shinji Fukuda, Yasuhiro Gotoh, Keiji Nakamura, Tetsuya Hayashi, Yoshiyuki Kasahara, Yukuto Sato, Shin Fukudo
Publikováno v:
Journal of Gastroenterology. 57:748-760
Background Irritable bowel syndrome (IBS) is a disorder of gut–brain interaction, including dysregulation of the hypothalamic–pituitary–adrenal axis with salivary cortisol changes. However, the role of gastrointestinal microbiota during IBS sym