Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Ritva, Tikkanen"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/6b24bb438db742518cf4f7910ada7117
Autor:
Miroslava Didiasova, Samuele Cesaro, Simon Feldhoff, Ilaria Bettin, Nana Tiegel, Vera Füssgen, Mariarita Bertoldi, Ritva Tikkanen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5237 (2024)
Succinic semialdehyde dehydrogenase (SSADH) is a mitochondrial enzyme involved in the catabolism of the neurotransmitter γ-amino butyric acid. Pathogenic variants in the gene encoding this enzyme cause SSADH deficiency, a developmental disease that
Externí odkaz:
https://doaj.org/article/35209843c6534c3dbabfab12d3c713ca
Autor:
Thomas Schmitt, Christoph Hudemann, Sina Moztarzadeh, Michael Hertl, Ritva Tikkanen, Jens Waschke
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPemphigus is an autoantibody driven disease that impairs the barrier function of the skin and mucosa by disrupting desmosomes and thereby impeding cellular cohesion. It is known that the different clinical phenotypes of pemphigus vulgaris
Externí odkaz:
https://doaj.org/article/5b41d7ba431f4dc7be55d92a1827209e
Autor:
Johanna Uusimaa, Johannes Kettunen, Teppo Varilo, Irma Järvelä, Jukka Kallijärvi, Helena Kääriäinen, Minna Laine, Risto Lapatto, Päivi Myllynen, Harri Niinikoski, Elisa Rahikkala, Anu Suomalainen, Ritva Tikkanen, Henna Tyynismaa, Päivi Vieira, Tomas Zarybnicky, Petra Sipilä, Satu Kuure, Reetta Hinttala
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 10 (2022)
Externí odkaz:
https://doaj.org/article/2a119f42fcfd41c2a9c6dcffb987c478
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5722 (2023)
Novel treatment strategies are emerging for rare, genetic diseases, resulting in clinical trials that require adequate biomarkers for the assessment of the treatment effect. For enzyme defects, biomarkers that can be assessed from patient serum, such
Externí odkaz:
https://doaj.org/article/48e50411914446b4a6d40127eb88123e
Autor:
Arttu Ruohola, Eero Salli, Timo Roine, Anna Tokola, Minna Laine, Ritva Tikkanen, Sauli Savolainen, Taina Autti
Publikováno v:
Brain Sciences, Vol 12, Iss 11, p 1522 (2022)
Magnetic resonance (MR) imaging data can be used to develop computer-assisted diagnostic tools for neurodegenerative diseases such as aspartylglucosaminuria (AGU) and other lysosomal storage disorders. MR images contain features that are suitable for
Externí odkaz:
https://doaj.org/article/665d81303728478aa2fc3fbfcec87fc0
Autor:
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen
Publikováno v:
Cells, Vol 11, Iss 10, p 1700 (2022)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/61896ac700a94631a0d52eeb793152df
Autor:
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen
Publikováno v:
Cells, Vol 11, Iss 6, p 942 (2022)
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have s
Externí odkaz:
https://doaj.org/article/94bff078217b4747b791e79e694256c3
Autor:
Ada-Sophia Clees, Verena Stolp, Björn Häupl, Dominik C. Fuhrmann, Frank Wempe, Marcel Seibert, Sarah Weber, Antje Banning, Ritva Tikkanen, Richard Williams, Bernhard Brüne, Hubert Serve, Frank Schnütgen, Ivana von Metzler, Nina Kurrle
Publikováno v:
Cells, Vol 11, Iss 2, p 292 (2022)
Multiple myeloma (MM) is the second most common hematologic malignancy, which is characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This microenvironment is characterized by low oxygen levels (1–6% O2), known as hy
Externí odkaz:
https://doaj.org/article/deddf1251dd84b8d8b830f691dc2792f
Autor:
Ritva Tikkanen
Publikováno v:
Cells, Vol 11, Iss 1, p 36 (2021)
Lysosomal storage disorders (LSDs) are rare, monogenic diseases characterized by aberrant lysosomes with storage material [...]
Externí odkaz:
https://doaj.org/article/30438ac8bb4c4d0bbdf64e5f5f85c3ff