Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ritu Jaiswal"'
Autor:
Ritu Jaiswal, Lisa M. Sedger
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Intercellular communication is a normal feature of most physiological interactions between cells in healthy organisms. While cells communicate directly through intimate physiology contact, other mechanisms of communication exist, such as through the
Externí odkaz:
https://doaj.org/article/b37d13b29cb84c09b57d33c23341b00f
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61515 (2013)
Microparticles (MPs) play a vital role in cell communication by facilitating the horizontal transfer of cargo between cells. Recently, we described a novel "non-genetic" mechanism for the acquisition of multidrug resistance (MDR) in cancer cells by i
Externí odkaz:
https://doaj.org/article/8cbb90dedac54f9c83af544e8c26f35d
Autor:
Deep Pokharel, Matthew P. Padula, Jamie F. Lu, Ritu Jaiswal, Steven P. Djordjevic, Mary Bebawy
Publikováno v:
Molecules, Vol 21, Iss 3, p 290 (2016)
Multidrug resistance (MDR) is often attributed to the over-expression of P-glycoprotein (P-gp), which prevents the accumulation of anticancer drugs within cells by virtue of its active drug efflux capacity. We have previously described the intercellu
Externí odkaz:
https://doaj.org/article/eedad103e4014c6d8ae0950321dd1678
Publikováno v:
International Journal of Oncology. 49:33-50
Multiple myeloma (MM) is a mature B cell neoplasm that results in multi-organ failure. The median age of onset, diverse clinical manifestations, heterogeneous survival rate, clonal evolution, intrinsic and acquired drug resistance have impact on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83162882be8340a801f3f53ce120469
https://doi.org/10.3892/ijo.2016.3516
https://doi.org/10.3892/ijo.2016.3516
Publikováno v:
European Journal of Pharmacology. 721:116-125
Expanding on our previous findings demonstrating that microparticles (MPs) spread cancer multidrug resistance, we now show that MPs sequester drugs, reducing the free drug concentration available to cells. MPs were isolated from drug-sensitive and dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87445f4b5866a18d82eee7b74ad49e12
https://doi.org/10.1016/j.ejphar.2013.09.044
https://doi.org/10.1016/j.ejphar.2013.09.044
Publikováno v:
Pharmacological Research. 76:77-83
Multidrug resistance (MDR) is a major impediment to the overall success of chemotherapy in clinical oncology. MDR has been primarily attributed by the ATP-dependent transmembrane proteins, P-glycoprotein (P-gp, ABCB1) and Multidrug Resistance-Associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fd81dd6e565d6a808bddb9b3a1a38a
https://doi.org/10.1016/j.phrs.2013.07.009
https://doi.org/10.1016/j.phrs.2013.07.009
© 2017 Bentham Science Publishers. Background: Multidrug resistance in cancer (MDR) occurs when tumours become crossresistant to a range of different anticancer agents. One mechanism by which MDR can be acquired is through cell to cell communication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e5216bbb1b7a6d2de567d2de47b173
https://hdl.handle.net/10453/125567
https://hdl.handle.net/10453/125567
Autor:
Mary Bebawy, Steven P. Djordjevic, Deep Pokharel, Ritu Jaiswal, Jamie F. Lu, Matthew P. Padula
Publikováno v:
Molecules
Molecules, Vol 21, Iss 3, p 290 (2016)
Molecules; Volume 21; Issue 3; Pages: 290
Molecules, Vol 21, Iss 3, p 290 (2016)
Molecules; Volume 21; Issue 3; Pages: 290
© 2016 by the authors. Multidrug resistance (MDR) is often attributed to the over-expression of P-glycoprotein (P-gp), which prevents the accumulation of anticancer drugs within cells by virtue of its active drug efflux capacity. We have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba965ddc5646573fd74e99a32dc610db
https://hdl.handle.net/10453/43767
https://hdl.handle.net/10453/43767
Microparticles in cancer: A review of recent developments and the potential for clinical application
© 2015 . Once thought of as inert remnants of cellular processes, the significance of membrane vesicles is now expanding as their capacity to package and transfer bioactive molecules during intercellular communication is established. This ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e830cc422531964cb6b4123228b244ee
https://hdl.handle.net/10453/35245
https://hdl.handle.net/10453/35245
Publikováno v:
Future oncology (London, England). 10(4)
ABSTRACT: Multidrug resistance (MDR) continues to be a major impediment to the successful treatment of cancer. The two efflux transporters, P-glycoprotein (P-gp) and MRP1 are major contributors to cancer MDR clinically. The upregulation of P-gp leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c787e8f17507eb702033994649e7f6
https://pubmed.ncbi.nlm.nih.gov/24754595
https://pubmed.ncbi.nlm.nih.gov/24754595