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Control of High Affinity Interactions in the Talin C Terminus: HOW TALIN DOMAINS COORDINATE PROTEIN DYNAMICS IN CELL ADHESIONS*S⃞

Autor: Himmel, Mirko, Ritter, Anett, Rothemund, Sven, Pauling, Björg V., Rottner, Klemens, Gingras, Alexandre R., Ziegler, Wolfgang H.

In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of integrins to the actin cytoskeleton. Talin is thought to mediate this connection via its two integrin, (at least) three actin, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::724fc975b682d9fc655e0e26f3f9e4b4
https://europepmc.org/articles/PMC2679484/

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Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

Autor: Himmel M; Interdisciplinary Centre for Clinical Research (IZKF) Leipzig, Faculty of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Ritter A; Interdisciplinary Centre for Clinical Research (IZKF) Leipzig, Faculty of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Rothemund S; Interdisciplinary Centre for Clinical Research (IZKF) Leipzig, Faculty of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Pauling BV; Zoological Institute, Technical University of Braunschweig, D-38106 Braunschweig, Germany., Rottner K; Cytoskeleton Dynamics Group, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany., Gingras AR; Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom., Ziegler WH; Interdisciplinary Centre for Clinical Research (IZKF) Leipzig, Faculty of Medicine, University of Leipzig, D-04103 Leipzig, Germany. Electronic address: wolfgang.ziegler@medizin.uni-leipzig.de.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2009 May 15; Vol. 284 (20), pp. 13832-13842. Date of Electronic Publication: 2009 Mar 11.