Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ritsumi Saito"'
Autor:
Yoshihiro Furukawa, Daisuke Saigusa, Kuniyuki Kano, Akira Uruno, Ritsumi Saito, Motoo Ito, Megumi Matsumoto, Junken Aoki, Masayuki Yamamoto, Tomoki Nakamura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Carbonaceous meteorites contain diverse soluble organic compounds. These compounds formed in the early solar system from volatiles accreted on tiny dust particles. However, the difference in the organic synthesis on respective dust particles
Externí odkaz:
https://doaj.org/article/57af2bc081ad4a6d84291a59fe6dd170
Autor:
Yexin Liu, Akira Uruno, Ritsumi Saito, Naomi Matsukawa, Eiji Hishinuma, Daisuke Saigusa, Hong Liu, Masayuki Yamamoto
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102525- (2022)
Oxidative stress is an essential component in the progression of diabetic kidney disease (DKD), and the transcription factor NF-E2-related factor-2 (Nrf2) plays critical roles in protecting the body against oxidative stress. To clarify the roles of N
Externí odkaz:
https://doaj.org/article/10475ee0c04f4bf09004d7d1a33f2fa8
Autor:
Koichi Kikuchi, Daisuke Saigusa, Yoshitomi Kanemitsu, Yotaro Matsumoto, Paxton Thanai, Naoto Suzuki, Koki Mise, Hiroaki Yamaguchi, Tomohiro Nakamura, Kei Asaji, Chikahisa Mukawa, Hiroki Tsukamoto, Toshihiro Sato, Yoshitsugu Oikawa, Tomoyuki Iwasaki, Yuji Oe, Tomoya Tsukimi, Noriko N. Fukuda, Hsin-Jung HO, Fumika Nanto-Hara, Jiro Ogura, Ritsumi Saito, Shizuko Nagao, Yusuke Ohsaki, Satoshi Shimada, Takehiro Suzuki, Takafumi Toyohara, Eikan Mishima, Hisato Shima, Yasutoshi Akiyama, Yukako Akiyama, Mariko Ichijo, Tetsuro Matsuhashi, Akihiro Matsuo, Yoshiaki Ogata, Ching-Chin Yang, Chitose Suzuki, Matthew C. Breeggemann, Jurgen Heymann, Miho Shimizu, Susumu Ogawa, Nobuyuki Takahashi, Takashi Suzuki, Yuji Owada, Shigeo Kure, Nariyasu Mano, Tomoyoshi Soga, Takashi Wada, Jeffrey B. Kopp, Shinji Fukuda, Atsushi Hozawa, Masayuki Yamamoto, Sadayoshi Ito, Jun Wada, Yoshihisa Tomioka, Takaaki Abe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Diabetes is a major cause of kidney disease. Here Kikuchi et al. show that phenol sulfate, a gut microbiota-derived metabolite, is increased in diabetic kidney disease and contributes to the pathology by promoting kidney injury, suggesting phenyl sul
Externí odkaz:
https://doaj.org/article/4b7ee8aaa8cd44e3ba881e3d9e920e28
Autor:
Yoko Yagishita, Akira Uruno, Toshiaki Fukutomi, Ritsumi Saito, Daisuke Saigusa, Jingbo Pi, Akiyoshi Fukamizu, Fumihiro Sugiyama, Satoru Takahashi, Masayuki Yamamoto
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 2030-2044 (2017)
The relationship between loss of hypothalamic function and onset of diabetes mellitus remains elusive. Therefore, we generated a targeted oxidative-stress murine model utilizing conditional knockout (KO) of selenocysteine-tRNA (Trsp) using rat-insuli
Externí odkaz:
https://doaj.org/article/7a1ad881d3ae42ce90c6541aca76e4d4
Autor:
Xiaodong Shao, Ryuta Saito, Aya Sato, Saori Okuno, Daisuke Saigusa, Ritsumi Saito, Akira Uruno, Yoshinari Osada, Masayuki Kanamori, Teiji Tominaga
Publikováno v:
Tohoku Journal of Experimental Medicine; Nov2023, Vol. 261 Issue 3, p187-194, 8p
Autor:
Daisuke Saigusa, Ritsumi Saito, Komei Kawamoto, Akira Uruno, Kuniyuki Kano, Shuichi Shimma, Junken Aoki, Masayuki Yamamoto, Tadafumi Kawamoto
Publikováno v:
Mass Spectrometry (2187-137X); 2023, Vol. 12, p1-6, 6p
Autor:
Harit Panda, Mikiko Suzuki, Mitsuru Naito, Ritsumi Saito, Huaichun Wen, Liam Baird, Akira Uruno, Kanjiro Miyata, Masayuki Yamamoto
Publikováno v:
Free radical biologymedicine. 187
The Keap1-Nrf2 system is the master regulator of the cellular response against oxidative and xenobiotic stresses. Constitutive activation of Nrf2 is frequently observed in various types of cancers. Nrf2 hyperactivation induces metabolic reprogramming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426bad13da72a953a43fbfb696c8c76c
https://pubmed.ncbi.nlm.nih.gov/35618180
https://pubmed.ncbi.nlm.nih.gov/35618180
Autor:
Emiko Sato, Yuji Oe, Daisuke Saigusa, Hiroshi Sato, Ritsumi Saito, Sadayoshi Ito, Yoshiko Kawana, Akiyo Sekimoto, Nobuyuki Takahashi, Manami Kaneko, Yukako Tsunokuni, Shuichi Shimma
Publikováno v:
Biochemical and Biophysical Research Communications. 527:1064-1071
Preeclampsia (PE) is a leading cause of maternal morbidity and mortality. Nicotinamide has beneficial effects on PE. In this study, we evaluated the effect of nicotinamide on placental development using a PE mouse model. To generate the PE model, a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65907a88032d46f49f696b0dbe162a3c
https://doi.org/10.1016/j.bbrc.2020.04.079
https://doi.org/10.1016/j.bbrc.2020.04.079
Autor:
Ritsumi Saito, Teiji Tominaga, Masayuki Yamamoto, Daisuke Saigusa, Takahiro Yamazaki, Yoshihisa Tomioka, Akira Uruno, Yotaro Matsumoto, Sherif Rashad, Kuniyasu Niizuma
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Understanding the root causes of neuronal vulnerability to ischemia is paramount to the development of new therapies for stroke. Transient global cerebral ischemia (tGCI) leads to selective neuronal cell death in the CA1 sub-region of the hippocampus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed147a8a9ef0918ee1c64b77ecd04d2
http://link.springer.com/article/10.1038/s41598-020-63483-w
http://link.springer.com/article/10.1038/s41598-020-63483-w
Autor:
Emiko Sato, Daisuke Saigusa, Eikan Mishima, Taeko Uchida, Daisuke Miura, Tomomi Morikawa-Ichinose, Kiyomi Kisu, Akiyo Sekimoto, Ritsumi Saito, Yuji Oe, Yotaro Matsumoto, Yoshihisa Tomioka, Takefumi Mori, Nobuyuki Takahashi, Hiroshi Sato, Takaaki Abe, Toshimitsu Niwa, Sadayoshi Ito
Publikováno v:
Toxins, Vol 10, Iss 1, p 19 (2017)
Elevated circulating uremic toxins are associated with a variety of symptoms and organ dysfunction observed in patients with chronic kidney disease (CKD). Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are representative uremic toxins that exert var
Externí odkaz:
https://doaj.org/article/d25f222df81b440280857dbceb85f58e