Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ritsuko Umeshita"'
Autor:
Jun Hiratake, Suzuki Tadao, Jun'ichi Oda, Akihiro Shinzaki, Hiroshi Nakajima, Takuji Nakatani, Ritsuko Umeshita, Takaaki Nishioka
Publikováno v:
Tetrahedron Letters. 34:4945-4948
A catalytic antibody capable of stereoselective ester hydrolysis was obtained. Chemical modification revealed that an Arg residue in the antibody combining site was responsible not only for the catalytic activity. but also for product inhibition by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::898d29b32dd16ea58ac61643bf1063f5
https://doi.org/10.1016/s0040-4039(00)74053-6
https://doi.org/10.1016/s0040-4039(00)74053-6
ChemInform Abstract: Toward the Antibody-Catalyzed Chemiluminescence. Design and Synthesis of Hapten
Autor:
Jun Hiratake, Yasuhiro Imaeda, Masayoshi Watanabe, H. Knodo, Ritsuko Umeshita, Masaaki Sawa, Jun'ichi Oda, Ryota Fujii
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d4886bf2b225b83bbdaec17c0f1977
https://doi.org/10.1002/chin.199828183
https://doi.org/10.1002/chin.199828183
Autor:
Tetsuji Yamashita, Shin-ichiro Shimazu, Xiao-Quan Mao, Ritsuko Umeshita-Suyama, Mohamad H. Sayegh, Mina Akaiwa, Julian M. Hopkin, Scott R. Brodeur, Yasuhisa Sakata, Raj K. Puri, Kazuhiko Arima, Naoto Sugawara, Yoshio Dake, Raif S. Geha, Naotaka Hamasaki, Chaker N. Adra, Kenji Izuhara, T. Shirakawa, Tadao Enomoto
Publikováno v:
The Journal of allergy and clinical immunology. 109(6)
Background: A substantial body of evidence exists to support the pivotal role of IL-13 in the pathogenesis of bronchial asthma. We recently found that a variant of the IL13 gene (Arg110Gln) is genetically associated with bronchial asthma, which is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094c7d347f293d8702adfda1fbebe9fe
https://pubmed.ncbi.nlm.nih.gov/12063528
https://pubmed.ncbi.nlm.nih.gov/12063528
Autor:
Mina Akaiwa, Bin Yu, Kazuhiko Arima, Nobuhisa Terada, Kenji Izuhara, Naotaka Hamasaki, Koichi Ohshima, Hideoki Ogawa, Tetsuya Koga, Hajime Suto, Hirohisa Saito, Masutaka Furue, Sho Matsushita, Ritsuko Umeshita-Suyama
Publikováno v:
Cytokine. 13(2)
Although the functional roles of interleukin (IL-)13 in haematopoietic cells are well investigated, those in non-haematopoietic cells remain to be addressed. IL-13 exerts its actions by binding to the IL-13 receptor (IL-13R) on target cells, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c323b03436d36386bcda35449c688e6
https://pubmed.ncbi.nlm.nih.gov/11145846
https://pubmed.ncbi.nlm.nih.gov/11145846
Autor:
Julian M. Hopkin, Kenji Izuhara, Ritsuko Umeshita-Suyama, Kazuhiko Arima, Naotaka Hamasaki, Mina Akaiwa, Klaus A. Deichmann, T. Shirakawa
Publikováno v:
Inflammation ISBN: 9789048158522
The prevalence of allergic disease has dramatically increased in recent decades, especially in urban and industrialized areas. Allergic diseases are disorders of the immune system, the results of complex interactions among various genetic and environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1501cd3dbc2abc92b11b226406066f5d
https://doi.org/10.1007/978-94-015-9702-9_10
https://doi.org/10.1007/978-94-015-9702-9_10
Autor:
Morimasa Wada, Mina Akaiwa, Ritsuko Umeshita-Suyama, Bin Yu, Kenji Izuhara, Koichi Nakajima, Kazuhiko Arima, Rie Sugimoto, Naotaka Hamasaki, Michihiko Kuwano
Publikováno v:
Scopus-Elsevier
IL-4 and IL-13 are pleiotropic cytokines whose biological activities overlap with each other. IL-13 receptor alpha chain 1 (IL-13R alpha 1) is necessary for binding to IL-13, and the heterodimer composed of IL-13R alpha 1 and IL-4R alpha chain transd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d115d5a71164720eb1b99bd6aa40e335
https://pubmed.ncbi.nlm.nih.gov/11058569
https://pubmed.ncbi.nlm.nih.gov/11058569
Autor:
Jun'ichi Oda, Hiroshi Nakajima, Ritsuko Umeshita, Takuji Nakatani, Jun Hiratake, Akihiro Shinzaki, Suzuki Tadao
Publikováno v:
Bioorganicmedicinal chemistry. 2(6)
A catalytic antibody which catalyzes stereoselective ester hydrolysis was characterized, and the role of a catalytic Arg residue is discussed in terms of product inhibition. A monoclonal antibody 1C7 generated against the phosphonate 1 was highly ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f7d19fa6c8ea74fc4cec7f4db02433
https://pubmed.ncbi.nlm.nih.gov/8000868
https://pubmed.ncbi.nlm.nih.gov/8000868