Precursor-Independent Overproduction of Beta-Amyloid in AD: Mitochondrial Dysfunction as Possible Initiator of Asymmetric RNA-Dependent βAPP mRNA Amplification. An Engine that Drives Alzheimer’s Disease

Autor: Volloch, Bjorn R. Olsen, Rits S

Publikováno v: Annals of Integrative Molecular Medicine. 1

The present study defines RNA-dependent amplification of βAPP mRNA as a molecular basis of beta-amyloid overproduction in Alzheimer’s disease. In this process, βAPP mRNA serves as a template for RNA-dependent RNA polymerase, RdRp complex. The res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd3411c443658763831d25e1ea576b27
https://doi.org/10.33597/aimm.01-1005

WS01.6 Antifibrinolytics therapy for treatment of hemoptysis in adults with cystic fibrosis; does it affect lung function?

Autor: Cardoni, L., Perkins, R., Shin, K., Al-Samkari, H., Pighetti, E., Rits, S., McMahon, L., Connors, J., Uluer, A.

Publikováno v: In Journal of Cystic Fibrosis June 2020 19 Supplement 2:S2-S2

Alzheimer's Disease Prevention and Treatment: Case for Optimism.

Autor: Volloch V; Department of Developmental Biology, Harvard School of Dental Medicine, USA., Olsen B; Department of Developmental Biology, Harvard School of Dental Medicine, USA., Rits S; Division of Molecular Medicine, Children's Hospital, Boston, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, USA.

Publikováno v: Annals of integrative molecular medicine [Ann Integr Mol Med] 2020; Vol. 2 (1), pp. 115-130.

AD "Statin": Alzheimer's Disorder is a "Fast" Disease Preventable by Therapeutic Intervention Initiated Even Late in Life and Reversible at the Early Stages.

Autor: Volloch V; Department of Developmental Biology, Harvard School of Dental Medicine, USA., Olsen BR; Department of Developmental Biology, Harvard School of Dental Medicine, USA., Rits S; Division of Molecular Medicine, Children's Hospital, Boston, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, USA.

Publikováno v: Annals of integrative molecular medicine [Ann Integr Mol Med] 2020; Vol. 2 (1), pp. 75-89.

Antifibrinolytic Agents for Hemoptysis Management in Adults With Cystic Fibrosis.

Autor: Al-Samkari H; Division of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA. Electronic address: hal-samkari@mgh.harvard.edu., Shin K; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA., Cardoni L; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA., Pighetti EH; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA., Rits S; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA., McMahon L; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA., Perkins R; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA., Uluer A; Division of Pulmonary and Respiratory Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA., Connors JM; Division of Hematology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA.

Publikováno v: Chest [Chest] 2019 Jun; Vol. 155 (6), pp. 1226-1233. Date of Electronic Publication: 2019 Feb 18.