Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ritika Kar"'
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-21 (2024)
Abstract In its myriad devastating forms, Tuberculosis (TB) has existed for centuries, and humanity is still affected by it. Mycobacterium tuberculosis (M. tuberculosis), the causative agent of TB, was the foremost killer among infectious agents unti
Externí odkaz:
https://doaj.org/article/44cd4a97809244ee829ff224a140176a
Publikováno v:
Biology Open, Vol 7, Iss 1 (2018)
Previously we had developed a triple gene mutant of Mycobacterium tuberculosis (MtbΔmms) harboring disruption in three genes, namely mptpA, mptpB and sapM. Though vaccination with MtbΔmms strain induced protection in the lungs of guinea pigs, the m
Externí odkaz:
https://doaj.org/article/e91df8487c4b4deea5ce22b9ca866498
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179513 (2017)
Owing to the devastation caused by tuberculosis along with the unsatisfactory performance of the Bacillus Calmette-Guérin (BCG) vaccine, a more efficient vaccine than BCG is required for the global control of tuberculosis. A number of studies have d
Externí odkaz:
https://doaj.org/article/25a3cef352a64dc6be0109af0b5f93f2
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22441 (2011)
Tuberculosis (TB) continues to pose a serious challenge to human health afflicting a large number of people throughout the world. In spite of the availability of drugs for the treatment of TB, the non-compliance to 6-9 months long chemotherapeutic re
Externí odkaz:
https://doaj.org/article/9e8c1e013807413eb96df1ee029f8a30
Akademický článek
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Publikováno v:
Drug Design, Development and Therapy
Background 7,8-Diaminopelargonic acid synthase (BioA), an enzyme of biotin biosynthesis pathway, is a well-known promising target for anti-tubercular drug development. Methods In this study, structure-based virtual screening was employed against the
Publikováno v:
Drug Design, Development and Therapy. 12:1065-1079
Background 7,8-Diaminopelargonic acid synthase (BioA), an enzyme of biotin biosynthesis pathway, is a well-known promising target for anti-tubercular drug development. Methods In this study, structure-based virtual screening was employed against the
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Tuberculosis (TB) is one of the major causes of mortality all over the globe. BCG, the only vaccine available against this disease has been successful in preventing the severe forms of childhood TB. However, the unsatisfactory performance of BCG in c
Publikováno v:
Journal of Nepal Medical Association, Vol 62, Iss 271 (2024)
Patan Academy of Health Sciences has been sending its undergraduate medical students to rural postings aligning with the national health system of Nepal to produce competent and empathetic healthcare professionals as a part of its social accountabili
Externí odkaz:
https://doaj.org/article/e037fc6860c74bcbae8c0e53590331a6
Publikováno v:
Biology Open
Biology Open, Vol 7, Iss 1 (2018)
Biology Open, Vol 7, Iss 1 (2018)
Previously we had developed a triple gene mutant of Mycobacterium tuberculosis (MtbΔmms) harboring disruption in three genes, namely mptpA, mptpB and sapM. Though vaccination with MtbΔmms strain induced protection in the lungs of guinea pigs, the m