Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ritesh Tichkule"'
Autor:
Jakub Fichna, Misha Bawa, Ganesh A Thakur, Ritesh Tichkule, Alexandros Makriyannis, Donna-Marie McCafferty, Keith A Sharkey, Martin Storr
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109115 (2014)
In an attempt to further investigate the role of cannabinoid (CB) system in the pathogenesis of inflammatory bowel diseases, we employed two recently developed ligands, AM841 (a covalently acting CB agonist) and CB13 (a peripherally-restricted CB ago
Externí odkaz:
https://doaj.org/article/87303222f8514ec89801914243b21c06
Autor:
Keith Jendza, Mitsunori Kato, Michael Salcius, Honnappa Srinivas, Andrea De Erkenez, Anh Nguyen, Doug McLaughlin, Celine Be, Christian Wiesmann, Jason Murphy, Philippe Bolduc, Muneto Mogi, Jose Duca, Abdel Namil, Michael Capparelli, Veronique Darsigny, Erik Meredith, Ritesh Tichkule, Luciana Ferrara, Jessica Heyder, Fang Liu, Patricia A. Horton, Michael J. Romanowski, Markus Schirle, Nello Mainolfi, Karen Anderson, Gregory A. Michaud
Publikováno v:
Nature chemical biology. 15(7)
The complement pathway is an important part of the immune system, and uncontrolled activation is implicated in many diseases. The human complement component 5 protein (C5) is a validated drug target within the complement pathway, as an anti-C5 antibo
Autor:
Nitin C. Patel, Ritesh Tichkule, Tomas Vasques, Gaurang Parmar, Jiejun Wu, Apurba Bhattacharya
Publikováno v:
Tetrahedron Letters. 47:565-567
A simple, surfactant-mediated, one-pot, solvent-free dealkylative cleavage of aryl ethers and esters followed by subsequent optional trans-alkylation under essentially neutral conditions has been developed.
Autor:
Apurba Bhattacharya, Gaurang Parmer, Ritesh Tichkule, Vikram C. Purohit, Frank Rinaldi, Victor Suarez
Publikováno v:
ChemInform. 37
A novel thioacetate mediated one-step reductive acetamidation of aryl nitro compounds was developed and applied to an efficient synthesis of acetaminophen. The reaction also proceeds well without a solvent in the presence of a catalytic amount of sur