Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ritesh K. Baboota"'
Autor:
Ritesh K. Baboota, Rosa Spinelli, Malin C. Erlandsson, Bruna B. Brandao, Marsel Lino, Hong Yang, Adil Mardinoglu, Maria I. Bokarewa, Jeremie Boucher, C. Ronald Kahn, Ulf Smith
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101558- (2022)
Objective: Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells have been identified in multiple tissues in different metabolic and other aging-
Externí odkaz:
https://doaj.org/article/82af05ba8e3a4d02a32750880a3b60a8
Autor:
Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie Boucher
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Cellular senescence is a state of irreversible cell cycle arrest and has been shown to play a key role in many diseases, including metabolic diseases. To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derang
Externí odkaz:
https://doaj.org/article/e07ac7d9dbb3475c9b853917c66c53c3
Autor:
Pragyanshu Khare, Priyanka Mangal, Ritesh K. Baboota, Sneha Jagtap, Vijay Kumar, Dhirendra Pratap Singh, Ravneet K. Boparai, Shyam S. Sharma, Romesh Khardori, Sanjay K. Bhadada, Kanthi K. Kondepudi, Kanwaljit Chopra, Mahendra Bishnoi
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Glucagon mediated mechanisms have been shown to play clinically significant role in energy expenditure. The present study was designed to understand whether pharmacological mimicking of cold using menthol (TRPM8 modulator) can induce glucagon-mediate
Externí odkaz:
https://doaj.org/article/f046d04019834b1b9f0f9e0c27ae758a
Autor:
Ritesh K. Baboota, Mahendra Bishnoi, Padma Ambalam, Kanthi Kiran Kondepudi, Siddhartha M. Sarma, Ravneet K. Boparai, Koteswaraiah Podili
Publikováno v:
Journal of Functional Foods, Vol 5, Iss 3, Pp 997-1012 (2013)
Worldwide obesity has reached a pandemic proportion. World Health Organization (WHO) estimates that by 2020, two thirds of the global disease burden will be attributable to obesity and obesity associated complications. Existing anti-obesity drugs, af
Externí odkaz:
https://doaj.org/article/cdae3e11ed674104a4af487fb6acc208
Autor:
Ritesh K. Baboota, Aidin Rawshani, Laurianne Bonnet, Xiangyu Li, Hong Yang, Adil Mardinoglu, Tamar Tchkonia, James L. Kirkland, Anne Hoffmann, Arne Dietrich, Jeremie Boucher, Matthias Blüher, Ulf Smith
Publikováno v:
Nature Metabolism. 4:1007-1021
The role of hepatic cell senescence in human non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is not well understood. To examine this, we performed liver biopsies and extensive characterization of 58 individuals with
Publikováno v:
Diabetes 70, 303-312 (2021)
Bone morphogenetic proteins (BMPs) are a group of signaling molecules that belong to the TGF-β superfamily. Initially discovered for their ability to induce bone formation, BMPs are known to play a diverse and critical array of biological roles. We
Autor:
Katleen Lemaire, Abhijit Babaji Shinde, Stefan Vinckier, Frans Schuit, Ritesh K. Baboota, Marc Fransen, Paul P. Van Veldhoven, Myriam Baes
Publikováno v:
Molecular Metabolism, Vol 22, Iss, Pp 71-83 (2019)
Molecular Metabolism
Molecular Metabolism
Objectives Peroxisomes play a crucial role in lipid and reactive oxygen species metabolism, but their importance for pancreatic β-cell functioning is presently unknown. To examine the contribution of peroxisomal metabolism to β-cell homeostasis in
Autor:
Jenny M. Hoffmann, Ivet Elias, Roxana Khatib Shahidi, Jeremie Boucher, Ann Hammarstedt, Christopher Church, Shahram Hedjazifar, Fatima Bosch, Laurianne Bonnet, Ritesh K. Baboota, Ulf Smith, Stephanie Heasman
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247300 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE
Objective Gremlin 1 (GREM1) is a secreted BMP2/4 inhibitor which regulates commitment and differentiation of human adipose precursor cells and prevents the browning effect of BMP4. GREM1 is an insulin antagonist and serum levels are high in type 2 di
Autor:
Ritesh K. Baboota, Kanthi Kiran Kondepudi, Jaspreet Kaur, Pragyanshu Khare, Kamlesh K. Bhutani, Dhirendra Pratap Singh, Mahendra Bishnoi, Priyanka Mangal
Publikováno v:
Nutrition Research. 51:40-56
Despite the lipolytic and thermogenic properties of capsaicin, its putative use as a weight-lowering dietary supplement has been limited because of the burning sensation caused by capsaicin when it comes in contact with mucous membranes. A potential
Autor:
Sacha Ferdinandusse, Marc Espeel, Ritesh K. Baboota, Ana R. Malheiro, Howard Riezman, Frédéric M. Vaz, Annelies Peeters, Abhijit Babaji Shinde, Stefan Vinckier, Paul P. Van Veldhoven, Simone Denis, Pedro Brites, Myriam Baes, Ursula Loizides-Mangold
Publikováno v:
Mitochondrion, Vol. 39 (2018) pp. 51-59
Mitochondrion, 39, 51-59. Elsevier
Mitochondrion, 39, 51-59. Elsevier
The structural disruption of the mitochondrial inner membrane in hepatocytes lacking functional peroxisomes along with selective impairment of respiratory complexes and depletion of mitochondrial DNA was previously reported. In search for the molecul