Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ritesh Bhanudasji Tichkule"'
Autor:
Victoriano Tamez, Brant Firestone, Michelle Fodor, Martin Sendzik, Michael G. Acker, Stan Spence, Matthew J. LaMarche, Mitsunori Kato, Chen Liu, Christopher Towler, Ping Wang, Ho Man Chan, Eric McNeill, Shumei Liu, Morvarid Mohseni, Sarah Williams, Zhouliang Chen, Gang Liu, Bing Yu, Robert Koenig, Huaixiang Hao, Ying-Nan Chen, Murphy Hentemann, Ritesh Bhanudasji Tichkule, Hongyun Wang, Jorge Garcia Fortanet, Laura R. LaBonte, Jeffrey T. Bagdanoff, Travis Stams, Patrick James Sarver
Publikováno v:
Journal of Medicinal Chemistry. 62:1793-1802
Protein tyrosine phosphatase SHP2 is an oncoprotein associated with cancer as well as a potential immune modulator because of its role in the programmed cell death PD-L1/PD-1 pathway. In the preceding manuscript, we described the optimization of a fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24d74ccebe527aac56b75855102ac3c
https://doi.org/10.1021/acs.jmedchem.8b01726
https://doi.org/10.1021/acs.jmedchem.8b01726
Autor:
Christopher Towler, Andriana Jouk, Murphy Hentemann, Matthew J. LaMarche, Bing Yu, Jorge Garcia Fortanet, Michelle Fodor, Hongyun Wang, Sarah Williams, Morvarid Mohseni, Shumei Liu, Huaixiang Hao, Ritesh Bhanudasji Tichkule, Ying-Nan Chen, Chen Liu, Ping Wang, Patrick James Sarver, Stan Spence, Laura R. LaBonte, Jeffrey T. Bagdanoff, Brant Firestone, Michael Shultz, Martin Sendzik, Eric McNeill, Zhouliang Chen, Gang Liu, Victoriano Tamez, Robert Koenig, Michael G. Acker, Ho Man Chan, Travis Stams, Mitsunori Kato
Publikováno v:
Journal of medicinal chemistry. 62(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385537f7a24ba5be8ef7298e05ce98f5
https://pubmed.ncbi.nlm.nih.gov/30688459
https://pubmed.ncbi.nlm.nih.gov/30688459
Autor:
Fabrizio C. Serluca, Kerstin Böhm, Michael B. Stadler, Markus Schirle, Vincent Acker, Johannes Ottl, Eric S. Fischer, Nicolas H. Thomä, Marc Hild, Haidi Yang, John R. Lydeard, Gondichatnahalli M. Lingaraju, Jane Nagel, J. Wade Harper, Simone Cavadini, William C. Forrester, Jeremy L. Jenkins, Ulrich Hassiepen, Rohan Eric John Beckwith, Ritesh Bhanudasji Tichkule, Michael Schebesta
Publikováno v:
Nature
In the 1950s, the drug thalidomide, administered as a sedative to pregnant women, led to the birth of thousands of children with multiple defects. Despite the teratogenicity of thalidomide and its derivatives lenalidomide and pomalidomide, these immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c9fbb3e2e9bc56076313c9b93ec35d
http://europepmc.org/articles/PMC4423819
http://europepmc.org/articles/PMC4423819
Autor:
Ulrich Hassiepen, Radosav S. Pantelic, Wassim Abdulrahman, Alessandro Potenza, Richard D. Bunker, Henning Stahlberg, Rohan Eric John Beckwith, Georg Petzold, Ritesh Bhanudasji Tichkule, Mahamadou Faty, Weaam I. Mohamed, Kaoru Sugasawa, Gondichatnahalli M. Lingaraju, Simone Cavadini, Kenneth N. Goldie, Eric S. Fischer, Syota Matsumoto, Nicolas H. Thomä
Publikováno v:
Nature
The cullin-RING ubiquitin E3 ligase (CRL) family comprises over 200 members in humans. The COP9 signalosome complex (CSN) regulates CRLs by removing their ubiquitin-like activator NEDD8. The CUL4A-RBX1-DDB1-DDB2 complex (CRL4A(DDB2)) monitors the gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0925a0cad2b0ad13bc284a1109e604eb
Autor:
Jonathan E. Grob, Ronald Tomlinson, Ritesh Bhanudasji Tichkule, Michael A. Dechantsreiter, Michael K. Connolly, Ayako Honda, Lawrence G. Hamann
Publikováno v:
Organic Letters. 14:5578-5581
Iterative cross-coupling is a highly efficient and versatile strategy for modular construction in organic synthesis, though this has historically been demonstrated solely in the context of C-C bond formation. A C-N cross-coupling of haloarene methyli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7222a1e1bd1878624a690ce53b13e7
https://doi.org/10.1021/ol302702q
https://doi.org/10.1021/ol302702q
Autor:
Lawrence G. Hamann, Jonathan E. Grob, Ronald Tomlinson, Michael K. Connolly, Ritesh Bhanudasji Tichkule, Ayako Honda, Michael A. Dechantsreiter
Publikováno v:
ChemInform. 44
In the presence of PAP and K3PO4 or LiHMDS, boronyl arenes undergo convenient amination to afford a wide range of arylamines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03d3b64119e7fc96a42fb67c04416fd5
https://doi.org/10.1002/chin.201312175
https://doi.org/10.1002/chin.201312175
Autor:
Margaret R. Pancost, Yanyi Zhu, Andrew McRiner, Jonathan E. Grob, Peter Atadja, Lewis Whitehead, Tommasi Ruben A, Travis Stams, Markus Dobler, Ping Wang, Wenlin Shao, Branko Radetich, Brian Edward Vash, Ritesh Bhanudasji Tichkule, Anup Patnaik, Michael Shultz, Tavina Claiborne
Publikováno v:
Bioorganicmedicinal chemistry. 19(15)
Herein we report the discovery of a family of novel yet simple, amino-acid derived class I HDAC inhibitors that demonstrate isoform selectivity via access to the internal acetate release channel. Isoform selectivity criteria is discussed on the basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226f867c89420283d21bf81c6617c3dc
https://pubmed.ncbi.nlm.nih.gov/21723733
https://pubmed.ncbi.nlm.nih.gov/21723733