Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Ritchie E. Brown"'
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 181-198 (2022)
Sleep abnormalities are widely reported in patients with Alzheimer’s disease (AD) and are linked to cognitive impairments. Sleep abnormalities could be potential biomarkers to detect AD since they are often observed at the preclinical stage. Moreov
Externí odkaz:
https://doaj.org/article/eafd97115a5949df9ee4c28a9ef2c631
Autor:
David S. Uygun, Chun Yang, Elena R. Tilli, Fumi Katsuki, Erik L. Hodges, James T. McKenna, James M. McNally, Ritchie E. Brown, Radhika Basheer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Uygun et al. show that deletion of GABAA receptors from the thalamic reticular nucleus using CRISPR gene editing in mice boosts the delta waves, indicating a role for GABAA receptors on thalamic reticular nucleus neurons in NREM sleep delta oscillati
Externí odkaz:
https://doaj.org/article/f103563cadb64548a47d87698d2e0166
Autor:
Ritchie E. Brown, Luis de Lecea
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/9f6180c22e2249d3972aef40e4321f7c
Autor:
Ritchie E. Brown, Gary B. Kaplan
Publikováno v:
Brain Research Bulletin, Vol 188, Iss , Pp 131-132 (2022)
Externí odkaz:
https://doaj.org/article/c5011c417bc443efb61febb4225bc463
Autor:
Chun Yang, Andrei Larin, James T. McKenna, Kenneth A. Jacobson, Stuart Winston, Robert E. Strecker, Anna Kalinchuk, Radhika Basheer, Ritchie E. Brown
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract The functions of purinergic P2 receptors (P2Rs) for extracellular adenosine triphosphate (ATP) are poorly understood. Here, for the first time, we show that activation of P2Rs in an important arousal region, the basal forebrain (BF), promote
Externí odkaz:
https://doaj.org/article/7b3e1e1e253041a2bc951220bd9dc89a
Chronic ketamine reduces the peak frequency of gamma oscillations in mouse prefrontal cortex ex vivo
Publikováno v:
Frontiers in Psychiatry, Vol 4 (2013)
Abnormalities in EEG gamma band oscillations (GBO, 30-80 Hz) serve as a prominent biomarker of schizophrenia (Sz), associated with positive, negative and cognitive symptoms. Chronic, subanesthetic administration of antagonists of N-methyl-D-aspartate
Externí odkaz:
https://doaj.org/article/3db8320b078f4e4faad2f92148938c8c
Autor:
Felipe L. Schiffino, James M. McNally, Eden B. Maness, James T. McKenna, Ritchie E. Brown, Robert E. Strecker
Publikováno v:
Journal of Sleep Research.
Autor:
Radhika Basheer, Stuart Winston, Fumi Katsuki, Marissa B Anderson-Chernishof, Ritchie E. Brown, James T. McKenna, James M. McNally, Chun Yang, Mackenzie C. Gamble, Abigail Hulverson, Thomas Bellio, John G. McCoy, Erik L. Hodges
Publikováno v:
Brain Struct Funct
The basal forebrain (BF) is involved in arousal, attention, and reward processing but the role of individual BF neuronal subtypes is still being uncovered. Glutamatergic neurons are the least well-understood of the three main BF neurotransmitter phen
Publikováno v:
Brain research bulletin. 185
Sleep disorders are widespread in society and are prevalent in military personnel and in Veterans. Disturbances of sleep and arousal mechanisms are common in neuropsychiatric disorders such as schizophrenia, post-traumatic stress disorder, anxiety an
Autor:
David S, Uygun, Chun, Yang, Elena R, Tilli, Fumi, Katsuki, Erik L, Hodges, James T, McKenna, James M, McNally, Ritchie E, Brown, Radhika, Basheer
Publikováno v:
Nature communications. 13(1)
Identification of mechanisms which increase deep sleep could lead to novel treatments which promote the restorative effects of sleep. Here, we show that knockdown of the α3 GABA