NusG-dependent RNA polymerase pausing is a common feature of riboswitch regulatory mechanisms.

Autor: Jayasinghe OT; Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, 203 Althouse, Pennsylvania State University, University Park, PA 16802, USA., Ritchey LE; Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, 203 Althouse, Pennsylvania State University, University Park, PA 16802, USA.; Department of Chemistry, 260 Engineering and Science, University of Pittsburgh at Johnstown, Johnstown, PA 15904, USA., Breil T; Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, 203 Althouse, Pennsylvania State University, University Park, PA 16802, USA., Newman P; Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, 203 Althouse, Pennsylvania State University, University Park, PA 16802, USA., Yakhnin H; Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, 203 Althouse, Pennsylvania State University, University Park, PA 16802, USA., Babitzke P; Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, 203 Althouse, Pennsylvania State University, University Park, PA 16802, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Nov 27; Vol. 52 (21), pp. 12945-12960.

mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity.

Autor: Waldron JA; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. J.Waldron@beatson.gla.ac.uk., Tack DC; Department of Biology, Pennsylvania State University, University Park, PA, 16802, USA.; Department of Chemistry, Pennsylvania State University, University Park, PA, 16802, USA.; Present Address: Spectrum Health Office of Research, 100 Michigan Street NE, Mail Code 038, Grand Rapids, MI, 49503, USA., Ritchey LE; Department of Chemistry, Pennsylvania State University, University Park, PA, 16802, USA.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA, 16802, USA.; Present Address: Department of Chemistry, University of Pittsburgh at Johnstown, Johnstown, PA, 15904, USA., Gillen SL; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Wilczynska A; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Turro E; Department of Haematology, University of Cambridge, Cambridge, UK.; Medical Research Council Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, UK.; National Health Service Blood and Transplant, Cambridge, UK.; National Institute for Health Research BioResource, Cambridge University Hospitals, Cambridge, UK., Bevilacqua PC; Department of Chemistry, Pennsylvania State University, University Park, PA, 16802, USA.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA, 16802, USA.; Department of Biochemistry & Molecular Biology, Pennsylvania State University, University Park, PA, 16802, USA., Assmann SM; Department of Biology, Pennsylvania State University, University Park, PA, 16802, USA.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA, 16802, USA., Bushell M; Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. m.bushell@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK. m.bushell@beatson.gla.ac.uk., Le Quesne J; Medical Research Council Toxicology Unit, University of Cambridge, Hodgkin Building, Lancaster Road, Leicester, LE1 7HB, UK. jlq2@leicester.ac.uk.; Leicester Cancer Research Centre, University of Leicester, Leicester, UK. jlq2@leicester.ac.uk.

Publikováno v: Genome biology [Genome Biol] 2019 Dec 30; Vol. 20 (1), pp. 300. Date of Electronic Publication: 2019 Dec 30.

Genome-wide RNA structurome reprogramming by acute heat shock globally regulates mRNA abundance.

Autor: Su Z; Department of Biology, Pennsylvania State University, University Park, PA 16802., Tang Y; Bioinformatics and Genomics Graduate Program, Pennsylvania State University, University Park, PA 16802., Ritchey LE; Department of Chemistry, Pennsylvania State University, University Park, PA 16802.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802., Tack DC; Department of Biology, Pennsylvania State University, University Park, PA 16802.; Department of Chemistry, Pennsylvania State University, University Park, PA 16802., Zhu M; Department of Biology, Pennsylvania State University, University Park, PA 16802., Bevilacqua PC; Department of Chemistry, Pennsylvania State University, University Park, PA 16802; pcb5@psu.edu sma3@psu.edu.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802.; Department of Biochemistry & Molecular Biology, Pennsylvania State University, University Park, PA 16802., Assmann SM; Department of Biology, Pennsylvania State University, University Park, PA 16802; pcb5@psu.edu sma3@psu.edu.; Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Nov 27; Vol. 115 (48), pp. 12170-12175. Date of Electronic Publication: 2018 Nov 09.

Glyoxals as in vivo RNA structural probes of guanine base-pairing.

Autor: Mitchell D 3rd; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Ritchey LE; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Park H; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Babitzke P; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Assmann SM; Department of Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Bevilacqua PC; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

Publikováno v: RNA (New York, N.Y.) [RNA] 2018 Jan; Vol. 24 (1), pp. 114-124. Date of Electronic Publication: 2017 Oct 13.

Eliminating blurry bands in gels with a simple cost-effective repair to the gel cassette.

Autor: Bingaman JL; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Frankel EA; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Hull CM; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Leamy KA; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Messina KJ; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Mitchell D 3rd; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Park H; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA., Ritchey LE; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA., Babitzke P; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA., Bevilacqua PC; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

Publikováno v: RNA (New York, N.Y.) [RNA] 2016 Dec; Vol. 22 (12), pp. 1929-1930. Date of Electronic Publication: 2016 Oct 19.