Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rita Upreti"'
Autor:
Gregorio Naredo-Gonzalez, Rita Upreti, Maurits A. Jansen, Scott Semple, Oliver B. Sutcliffe, Ian Marshall, Brian R. Walker, Ruth Andrew
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies tissue glucocorticoid levels and is a pharmaceutical target in diabetes and cognitive decline. Clinical translation of inhibitors is hampered by lack of in vivo pharmacodynamic b
Externí odkaz:
https://doaj.org/article/6a9028e7cc0f46658c806d04000708a5
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Increasing numbers of trans and gender diverse young people are presenting to health services seeking gender-affirming medical care. While testosterone therapy in transgender males is generally effective in inducing masculinization, some adolescents
Externí odkaz:
https://doaj.org/article/7bcc263f357541bea4f3da7357625fea
Australian fertility preservation guidelines for people with cancer 2022: review and recommendations
Autor:
Violet Kieu, Catharyn Stern, Jessica Harris, Yasmin Jayasinghe, Natalie Bradford, Wanyuan Cui, Rebecca Deans, Tamara Hunter, Catherine Allingham, Stefan C Kane, Lei Shong Lau, Shanna Logan, Robert McLachlan, Kristen Neville, Michelle Peate, Marianne Phillips, Carla Saunders, Marianne Tome, Rita Upreti, Kate White, Antoinette Anazodo, Roger J Hart
Publikováno v:
Medical Journal of Australia. 217:564-569
Publikováno v:
SN Comprehensive Clinical Medicine. 2:464-467
Hyperprolactinemia in premenopausal women often presents with amenorrhea, symptoms of estrogen deficiency and sub-fertility. After exclusion of other common causes and in the context of a normal pituitary MRI scan, hyperprolactinemia is typically dee
Autor:
Scott Semple, Oliver B. Sutcliffe, Gregorio Naredo-Gonzalez, Brian R. Walker, Ian Marshall, Rita Upreti, Maurits A. Jansen, Ruth Andrew
Publikováno v:
Naredo-Gonzalez, G, Upreti, R, Jansen, M A, Semple, S, Sutcliffe, O B, Marshall, I, Walker, B R & Andrew, R 2022, ' Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19 F-magnetic resonance spectroscopy ', Scientific Reports . https://doi.org/10.1038/s41598-022-18740-5
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies tissue glucocorticoid levels and is a pharmaceutical target in diabetes and cognitive decline. Clinical translation of inhibitors is hampered by lack of in vivo pharmacodynamic biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46dbfda0addb6e5dc4d569e04ffd9bd
https://doi.org/10.21203/rs.3.rs-943640/v1
https://doi.org/10.21203/rs.3.rs-943640/v1
Autor:
Gregorio, Naredo-Gonzalez, Rita, Upreti, Maurits A, Jansen, Scott, Semple, Oliver B, Sutcliffe, Ian, Marshall, Brian R, Walker, Ruth, Andrew
Publikováno v:
Scientific reports. 12(1)
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies tissue glucocorticoid levels and is a pharmaceutical target in diabetes and cognitive decline. Clinical translation of inhibitors is hampered by lack of in vivo pharmacodynamic biomarkers
Autor:
Diego Cobice, Rita Upreti, Fraser W. Gibb, Scott G. Denham, Ghazali Sabil, Abdullah M.M. Faqehi, Natalie Z.M. Homer, Shazia Khan, Joanna P Simpson, Gregorio Naredo, Ruth Andrew
Publikováno v:
Faqehi, A M, Denham, S, Naredo, G, Cobice, D F, Khan, S, Simpson, J, Sabil, G, Upreti, R, Gibb, F, Homer, N Z M & Andrew, R 2021, ' Derivatization with 2-Hydrazino-1-methylpyridine Enhances Sensitivity of Analysis of 5α-Dihydrotestosterone in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry ', Journal of Chromatography A . https://doi.org/10.1016/j.chroma.2021.461933
Journal of Chromatography. a
Journal of Chromatography. a
Highlights • Quantitative analysis of low abundance androgens in human plasma. • Quantitation of androgens over physiological range in men and post-menopausal women. • Use of hydrazine derivatives improves analytical sensitivity.
Liquid Ch
Liquid Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5498c80f659d99dc7df77e80d1e4485c
https://www.pure.ed.ac.uk/ws/files/196491667/DAEE9H_H.PDF
https://www.pure.ed.ac.uk/ws/files/196491667/DAEE9H_H.PDF
Autor:
Abdullah M.M. Faqehi, Fraser W. Gibb, Diego Cobice, Ruth Andrew, Scott Denham, Rita Upreti, Natalie Z.M. Homer, Ghazali Sabil, Gregorio Naredo-Gonzalezb
Publikováno v:
Endocrine Abstracts.
Autor:
Andreas Stomby, Johan Björkegren, Ruth Andrew, Brian R. Walker, Roland H Stimson, Ariella Cohain, Rita Upreti, Patrick W. F. Hadoke, Natalie Z.M. Homer, Tom Michoel, Eric E. Schadt, Arno Ruusalepp, Katharina Beck, Anna Anderson, René Houtman, Tommy Olsson, Mark Nixon, Christopher J. Kenyon, John Keen, Alex Odermatt, Onno C. Meijer, Diana Melchers, Ruth Morgan, Andrew A Crawford
Publikováno v:
Scientific Reports
Morgan, R A, Beck, K R, Nixon, M, Homer, N Z M, Crawford, A A, Melchers, D, Houtman, R, Meijer, O C, Stomby, A, Anderson, A J, Upreti, R, Stimson, R H, Olsson, T, Michoel, T, Cohain, A, Ruusalepp, A, Schadt, E E, Björkegren, J L M, Andrew, R, Kenyon, C J, Hadoke, P W F, Odermatt, A, Keen, J A & Walker, B R 2017, ' Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity ', Scientific Reports, vol. 7, no. 1, 10633 . https://doi.org/10.1038/s41598-017-10410-1
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Morgan, R A, Beck, K R, Nixon, M, Homer, N Z M, Crawford, A A, Melchers, D, Houtman, R, Meijer, O C, Stomby, A, Anderson, A J, Upreti, R, Stimson, R H, Olsson, T, Michoel, T, Cohain, A, Ruusalepp, A, Schadt, E E, Björkegren, J L M, Andrew, R, Kenyon, C J, Hadoke, P W F, Odermatt, A, Keen, J A & Walker, B R 2017, ' Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity ', Scientific Reports, vol. 7, 10633 . https://doi.org/10.1038/s41598-017-10410-1
Scientific Reports, 7
Morgan, R A, Beck, K R, Nixon, M, Homer, N Z M, Crawford, A A, Melchers, D, Houtman, R, Meijer, O C, Stomby, A, Anderson, A J, Upreti, R, Stimson, R H, Olsson, T, Michoel, T, Cohain, A, Ruusalepp, A, Schadt, E E, Björkegren, J L M, Andrew, R, Kenyon, C J, Hadoke, P W F, Odermatt, A, Keen, J A & Walker, B R 2017, ' Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity ', Scientific Reports, vol. 7, no. 1, 10633 . https://doi.org/10.1038/s41598-017-10410-1
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Morgan, R A, Beck, K R, Nixon, M, Homer, N Z M, Crawford, A A, Melchers, D, Houtman, R, Meijer, O C, Stomby, A, Anderson, A J, Upreti, R, Stimson, R H, Olsson, T, Michoel, T, Cohain, A, Ruusalepp, A, Schadt, E E, Björkegren, J L M, Andrew, R, Kenyon, C J, Hadoke, P W F, Odermatt, A, Keen, J A & Walker, B R 2017, ' Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity ', Scientific Reports, vol. 7, 10633 . https://doi.org/10.1038/s41598-017-10410-1
Scientific Reports, 7
Carbonyl Reductase 1 (CBR1) is a ubiquitously expressed cytosolic enzyme important in exogenous drug metabolism but the physiological function of which is unknown. Here, we describe a role for CBR1 in metabolism of glucocorticoids. CBR1 catalyzes the
Autor:
Fraser W, Gibb, Natalie Z M, Homer, Abdullah M M, Faqehi, Rita, Upreti, Dawn E, Livingstone, Kerry J, McInnes, Ruth, Andrew, Brian R, Walker
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context: Deficiency of aromatase, the enzyme that catalyzes the conversion of androgens to estrogens, is associated with insulin resistance in humans and mice. Objective: We hypothesized that pharmacological aromatase inhibition results in peripheral