Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rita Török"'
Publikováno v:
Parkinson's Disease, Vol 2015 (2015)
Background. There is substantial evidence that the kynurenine pathway (KP) plays a role in the normal physiology of the brain and is involved in the pathology of neurodegenerative disorders such as Huntington’s disease and Parkinson’s disease (PD
Externí odkaz:
https://doaj.org/article/6a9b482a1bea4988bc96d7e05a2d1bdf
Autor:
Zsofia Gabriella Pesei, András Salamon, Dénes Zádori, Evelin Sumegi, Péter Klivényi, Fanni Annamária Boros, Mate Molnar, Gábor Veres, Rita Török, László Vécsei
Publikováno v:
Neuroscience Letters. 698:13-18
Proper mitochondrial function is crucial for intact cellular homeostasis. Mitochondrial dysfunction is clearly involved in the pathogenesis of most neurodegenerative- and age-related chronic disorders. The aim of this study is to stimulate cellular p
Autor:
Evelin Sumegi, Dénes Zádori, Gabor Istvan Veres, András Salamon, Mate Molnar, László Vécsei, Péter Klivényi, Rita Török
Publikováno v:
Brain Research. 1660:20-26
The peroxisome proliferator-activated receptor-γ (PPARγ) coactivator 1α (PGC-1α) is a key regulator of mitochondrial biogenesis, respiration and adaptive thermogenesis. Besides the full-length protein (FL-PGC-1α), several other functionally acti
Autor:
Zsofia Gabriella Pesei, Fanni Annamária Boros, Evelin Vágvölgyi-Sümegi, Rita Török, Péter Klivényi, László Vécsei
Publikováno v:
Neuroscience letters. 706
Introduction Parkinson’s disease is the second most common neurodegenerative disease. Lifestyle, environmental effects and several genetic factors have been proposed to contribute to its development. Though the majority of PD cases do not have a fa
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
Huntington's disease is an autosomal dominant progressive neurodegenerative disease, which results in a decreased quality of life and an early death. A high prevalence of vitamin D deficiency was first described in a 2013 study in patients with manif
Autor:
Rita Török, László Vécsei, Péter Klivényi, Dénes Zádori, Gábor Veres, Emese Fazekas, Mate Molnar, István Ilisz, Márton Szentirmai, Levente Szalárdy
Publikováno v:
Pharmacology Biochemistry and Behavior. 132:115-124
Experiments on human samples and on genetic animal models of Huntington's disease (HD) suggest that a number of neuroactive metabolites in the kynurenine (KYN) pathway (KP) of the tryptophan (TRP) catabolism may play a role in the development of HD.
Publikováno v:
Parkinson's Disease, Vol 2015 (2015)
Parkinson's Disease
Parkinson's Disease
Background. There is substantial evidence that the kynurenine pathway (KP) plays a role in the normal physiology of the brain and is involved in the pathology of neurodegenerative disorders such as Huntington’s disease and Parkinson’s disease (PD
Autor:
Imola Plangár, Nóra Török, László Vécsei, Rita Török, Ferenc Somogyvári, Zoltán Szolnoki, Levente Szalárdy, Péter Klivényi
Publikováno v:
Neuroscience Letters. 551:70-74
Vitamin D receptor (VDR) gene encodes a transcription factor that influences calcium homeostasis and immunoregulation, and may play a role in neurological disorders including Parkinson's disease (PD). The investigations of the association between VDR
Autor:
Dénes Zádori, Rita Török, Péter Klivényi, Levente Szalárdy, László Vécsei, Mate Molnar, Gabor G. Kovacs
Publikováno v:
Behavioural brain research. 313
Impaired peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α) function has been demonstrated in several neurodegenerative diseases, and murine whole-body knockouts of PGC-1α have been considered as models for Huntington's d
Autor:
Zita Gajda, Rita Török, Laszlo Orfi, Zoltán Horváth, Magdolna Szente, György Kéri, Csaba Szántai-Kis
Publikováno v:
Epilepsia. 52:579-588
Summary Purpose: Effects of the “VID-82925” kinase inhibitor molecule were investigated both during the developing phase as well as during the stable phase of the focus with spontaneous recurrent seizures using the 4-AP-induced in vivo epilepsy m