Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Rita Setroikromo"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype independent of estrogen receptor, progesterone receptor, or human epidermal growth factor receptor 2. It has a poor prognosis and high recurrence. Due to its limited tr
Externí odkaz:
https://doaj.org/article/200ae127c7814f298c222918336733bd
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Tumor necrosis factor–related apoptosis inducing ligand (TRAIL) is considered to be a promising antitumor drug because of its selective proapoptotic properties on tumor cells. However, the clinical application of TRAIL is until now limited because
Externí odkaz:
https://doaj.org/article/97c0f6c280154b58be4462dff5229991
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The bacterial biofilm plays a key role in nosocomial infections, especially those related to medical devices in sustained contact with patients. The active dispersion of bacterial cells out of biofilms acts as a reservoir for infectious diseases. The
Externí odkaz:
https://doaj.org/article/3cb289373f5c432195d3ca33c10712d3
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 181 (2022)
The tumor necrosis factor (TNF) ligand family has nine ligands that show promiscuity in binding multiple receptors. As different receptors transduce into diverse pathways, the study on the functional role of natural ligands is very complex. In this r
Externí odkaz:
https://doaj.org/article/ddc19af6a4844e899190a5bf2235e72b
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Pseudomonas aeruginosa is the predominant pathogen in pulmonary infections associated with cystic fibrosis. Quorum sensing (QS) systems regulate the production of virulence factors and play an important role in the establishment of successful P. aeru
Externí odkaz:
https://doaj.org/article/3fdfda6a47bb4b6997645c5d37b9a7f7
Publikováno v:
Bioorganic Chemistry, 136:106546
Various diseases are deeply associated with aberrations in HDAC8 functions. These aberrations can be assigned to either structural functions or catalytic functions of HDAC8. Therefore, development of HDAC8 degradation inducers might be more promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc9492662efcf45a8eb34bc2e087c04
https://doi.org/10.1016/j.bioorg.2023.106546
https://doi.org/10.1016/j.bioorg.2023.106546
Autor:
Petra E van der Wouden, Zhangping Xiao, Frank J. Dekker, Deng Chen, Dea Gogishvili, Rita Setroikromo, Hao Guo
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(40), 21875-21883. WILEY-V C H VERLAG GMBH
Angewandte Chemie (International ed. in English), 60(40), 21875-21883. WILEY-V C H VERLAG GMBH
Lipoxygenase (LOX) activity provides oxidative lipid metabolites, which are involved in inflammatory disorders and tumorigenesis. Activity‐based probes to detect the activity of LOX enzymes in their cellular context provide opportunities to explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcaf1ff2001ab82da878efb2ea45452
https://doi.org/10.1002/anie.202106968
https://doi.org/10.1002/anie.202106968
Autor:
Jan G.T. Vogel, Joko P. Wibowo, Hillina Fan, Rita Setroikromo, Kan Wang, Alexander Dömling, Frank J. Dekker, Wim J. Quax
Publikováno v:
Microbes and infection, 24:105017. ELSEVIER SCIENCE BV
The acquisition of iron is a crucial mechanism for the survival of pathogenic bacteria such as Pseudomonas aeruginosa in eukaryotic hosts. The key iron chelator in this organism is the siderophore pyoverdine, which was shown to be crucial for iron ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa610065d8bd792b06d1cdc6d34fde6
https://research.rug.nl/en/publications/b69659aa-1277-49fc-a5fc-e0852f04f3c5
https://research.rug.nl/en/publications/b69659aa-1277-49fc-a5fc-e0852f04f3c5
Publikováno v:
Journal of applied microbiology. 133(4)
Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system has been developed into a precise and efficient genome editing tool. Since its discovery as an adaptive immune system in prokaryotes, it has been applied in many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742debdc644fcc4c92645fcb54284f52
https://pubmed.ncbi.nlm.nih.gov/35797344
https://pubmed.ncbi.nlm.nih.gov/35797344
Autor:
Ingy I Abdallah, Wim J. Quax, Ronald van Merkerk, Siqi He, Pieter G. Tepper, Anita Jopkiewicz, Yafeng Song, Rita Setroikromo
Publikováno v:
Journal of Agricultural and Food Chemistry
Journal of Agricultural and Food Chemistry, 69(16), 4785-4794. AMER CHEMICAL SOC
Journal of Agricultural and Food Chemistry, 69(16), 4785-4794. AMER CHEMICAL SOC
Engineering strategies to improve terpenoids production in Bacillus subtilis mainly focus on 2C-methyl-D-erythritol-4-phosphate (MEP) pathway overexpression. To systematically engineer the chassis strain for higher amorphadiene (precursor of artemisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553dd0157271f5e7cf0ba6b541b5460b
https://doi.org/10.1021/acs.jafc.1c00498
https://doi.org/10.1021/acs.jafc.1c00498