Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rita Schwaha"'
Autor:
Gerhard F. Ecker, Rita Schwaha
Publikováno v:
QSAR & Combinatorial Science. 28:834-839
As part of the ATP-binding cassette transporter superfamily P-glycoprotein (ABCB1) acts as xenotoxic exporter and consequently is strongly involved in multidrug resistance (MDR) and drug-drug interactions. In this work we focus on our in-house develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f582b5f0b31096f074d608e2c9d962e
https://doi.org/10.1002/qsar.200960051
https://doi.org/10.1002/qsar.200960051
Autor:
Peter Ettmayer, Eric E. J. Haaksma, Rita Schwaha, Gerhard F. Ecker, Michael A. Demel, Oliver Krämer
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 4:1167-1180
Overexpression of ABC (ATP-binding cassette)-type drug efflux pumps, such as ABCB1, ABCC1 and ABCG2 in cancer cells confers multi-drug resistance (MDR) and represents a major cause of treatment failures in cancer therapy. Furthermore, there is increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02502ee033c1ffa8f90db3c824c86da2
https://doi.org/10.1517/17425255.4.9.1167
https://doi.org/10.1517/17425255.4.9.1167
Autor:
Gerhard F. Ecker, Rita Schwaha
Publikováno v:
Scientia Pharmaceutica
Volume 76
Issue 1
Pages 5-18
Volume 76
Issue 1
Pages 5-18
Structural similarity is one of the basic underlying principles in drug discovery and development. Numerous algorithms and concepts are known to search compound libraries for analogous compounds assuming that similar compounds show similar biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c8461b283eb9b548a1c239ad01a046
https://doi.org/10.3797/scipharm.0802-05
https://doi.org/10.3797/scipharm.0802-05
Autor:
Rita Schwaha, Gerhard F. Ecker
Publikováno v:
Future medicinal chemistry. 3(9)
Background: The multidrug transporter P-glycoprotein (P-gp) ATP-binding cassette B1 (ABCB1) is one of the key proteins influencing bioavailability and uptake of drugs in the brain. In addition, it is one of the main factors contributing to multidrug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f4c77c74ad4fceda253ed7497c17f8
https://pubmed.ncbi.nlm.nih.gov/21806376
https://pubmed.ncbi.nlm.nih.gov/21806376