Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Rita Santamaria"'
Publikováno v:
Cancers, Vol 16, Iss 6, p 1220 (2024)
Based on the multifaceted molecular machinery that tightly controls iron cellular homeostasis, this review delves into its paradoxical, potentially dangerous role in biological systems, with a special focus on double-edged sword correlations with can
Externí odkaz:
https://doaj.org/article/068abf7277c54fd3a99b9033f5a8b213
Autor:
Claudia Cerracchio, Maria Grazia Amoroso, Marialuisa Piccolo, Maria Grazia Ferraro, Francesca Paola Nocera, Luisa De Martino, Francesco Serra, Carlo Irace, Gian Carlo Tenore, Ettore Novellino, Rita Santamaria, Filomena Fiorito
Publikováno v:
Virus Research, Vol 336, Iss , Pp 199217- (2023)
Bovine alphaherpesvirus 1 (BoAHV-1), the pathogen causing Infectious Bovine Rhinotracheitis (IBR) and predisposing to polymicrobial infections in cattle, provokes farm economic losses and trading restrictions in the world. However, nontoxic antiviral
Externí odkaz:
https://doaj.org/article/326c9e30d1cb4a639925757ca7b0aeb1
Autor:
Maria Grazia Ferraro, Marco Bocchetti, Claudia Riccardi, Marco Trifuoggi, Luigi Paduano, Daniela Montesarchio, Gabriella Misso, Rita Santamaria, Marialuisa Piccolo, Carlo Irace
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6473 (2023)
Based on compelling preclinical evidence concerning the progress of our novel ruthenium-based metallotherapeutics, we are focusing research efforts on challenging indications for the treatment of invasive neoplasms such as the triple-negative breast
Externí odkaz:
https://doaj.org/article/1105430457e54ce2b6fd562608f559f8
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 954 (2022)
Countless expectations converge in the multidisciplinary endeavour for the search and development of effective and safe drugs in fighting cancer. Although they still embody a minority of the pharmacological agents currently in clinical use, metal-bas
Externí odkaz:
https://doaj.org/article/02019956dab24a32a8224c912376a3ef
Autor:
Rosa Bellavita, Federica Raucci, Francesco Merlino, Marialuisa Piccolo, Maria Grazia Ferraro, Carlo Irace, Rita Santamaria, Asif J. Iqbal, Ettore Novellino, Paolo Grieco, Nicola Mascolo, Francesco Maione
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 123, Iss , Pp 109788- (2020)
Antimicrobial peptides (AMPs) are an ancient group of defense molecules distributed in nature being found in mammals, birds, amphibians, insects, plants, and microorganisms. They display antimicrobial as well as immunomodulatory properties. The aim o
Externí odkaz:
https://doaj.org/article/b7836a6af04d4f329ad52096ba9beece
Autor:
Marialuisa Piccolo, Maria Grazia Ferraro, Federica Raucci, Claudia Riccardi, Anella Saviano, Irene Russo Krauss, Marco Trifuoggi, Michele Caraglia, Luigi Paduano, Daniela Montesarchio, Francesco Maione, Gabriella Misso, Rita Santamaria, Carlo Irace
Publikováno v:
Cancers, Vol 13, Iss 20, p 5164 (2021)
Selectivity and efficacy towards target cancer cells, as well as biocompatibility, are current challenges of advanced chemotherapy powering the discovery of unconventional metal-based drugs and the search for novel therapeutic approaches. Among secon
Externí odkaz:
https://doaj.org/article/2b37bd89e6af4ce98a500d41acd4f43c
Autor:
Eriola Hoxha, Pellegrino Lippiello, Fabio Zurlo, Ilaria Balbo, Rita Santamaria, Filippo Tempia, Maria Concetta Miniaci
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
The role of the cerebellum in Alzheimer’s disease (AD) has been neglected for a long time. Recent studies carried out using transgenic mouse models have demonstrated that amyloid-β (Aβ) is deposited in the cerebellum and affects synaptic transmis
Externí odkaz:
https://doaj.org/article/b8035e4984974265ba88584a083446b0
Autor:
Maria Grazia Ferraro, Marialuisa Piccolo, Gabriella Misso, Francesco Maione, Daniela Montesarchio, Michele Caraglia, Luigi Paduano, Rita Santamaria, Carlo Irace
Publikováno v:
Cells, Vol 9, Iss 6, p 1412 (2020)
In this review we have showcased the preclinical development of original amphiphilic nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the current metallodrugs approach leading over the past decade to advanced mult
Externí odkaz:
https://doaj.org/article/cd756fc1b53648b589fb65baac3db765
Autor:
Rocco Vitalone, Rita Santamaria, Concetta Imperatore, Carlo Irace, Marialuisa Menna, Paolo Luciano, Ernesto Fattorusso, Anna Aiello
Publikováno v:
Marine Drugs, Vol 9, Iss 6, Pp 1157-1165 (2011)
Chemical analysis of the Mediterranean ascidian Polyandrocarpa zorritensis (Van Name 1931) resulted in the isolation of a series of molecules including two monoindole alkaloids, 3-indolylglyoxylic acid (3) and its methyl ester (4), 4-hydroxy-3-methox
Externí odkaz:
https://doaj.org/article/da28156ce5394f3bb0cc9e6eb32deaf0
Autor:
Filomena Fiorito, Carlo Irace, Antonio Di Pascale, Alfredo Colonna, Giuseppe Iovane, Ugo Pagnini, Rita Santamaria, Luisa De Martino
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58845 (2013)
Mammalian cells require iron to satisfy metabolic needs or to accomplish specialized functions, and DNA viruses, like bovine herpesvirus 1 (BHV-1), require an iron-replete host to efficiently replicate, so that iron bioavailability is an important co
Externí odkaz:
https://doaj.org/article/81a4e94eb50246d181e19b56213a2aa8