Synthesis, Characterization, and Antibacterial Activity Study of Novel Curcuminoids Derivatives

Autor: Mustafa M. AL-Hakiem, Mustafa Q. Alderawy, Riham Adnan, Rita S Elias

Publikováno v: Iraqi Journal of Pharmaceutical Sciences, Vol 33, Iss 1 (2024)

Curcumin is a well-known compound with broad spectrum biological activities, but unfortunately rapid degradation properties and low bioavailability. Therefore, several attempts have been made to overcome these obstructions through chemical modificati

Externí odkaz: https://doaj.org/article/eb6f4b5263f04bce87654fb444c082e5

Curcumin analogues for possible cancer treatment A QSAR and partial ordering study

Autor: Rita S. Elias, Bahjat A. Saeed, Poul Erik Hansen, Lars Carlsen

Publikováno v: World Journal of Biological and Pharmaceutical Research. 1:001-016

The possible effect of curcumin as a potential natural cancer treatment drug has been intensively discussed. In the present study the probabilities of a series of curcumin analogues to possess potential as antineoplastic, prostate cancer treatment an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a55726e54721938aef4b2df60ad7eaf
https://doi.org/10.53346/wjbpr.2021.1.2.0126

Strong intramolecular hydrogen bonds and steric effects involving C═S groups: An NMR and computational study

Autor: Rita S. Elias, Fadhil S. Kamounah, Fritz Duus, Bahjat A. Saeed, Poul Erik Hansen

Publikováno v: Elias, R S, Saeed, B A, Kamounah, F S, Duus, F & Hansen, P E 2020, ' Strong intramolecular hydrogen bonds and steric effects involving C═S groups : An NMR and computational study ', Magnetic Resonance in Chemistry, vol. 58, no. 2, pp. 154-162 . https://doi.org/10.1002/mrc.4959

A number of 5-acyl rhodanines and thiorhodanines with bulky acyl groups (pivaloyl and adamantoyl), not previously available, have been synthesized. The compounds are shown to exist in the enol form. Structures have been calculated using both the MP2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31af20e305390ec2252130e4a444e8f
https://doi.org/10.1002/mrc.4959

Synthesis, Ant Proliferative Activity and Docking Study of New Quercetin Derivatives against MDA-MB231 Breast Cancer Cell Lines

Autor: Shaker A. N. Al-Jadaan, Reham Adnan Al-Anssari, Rita S. Elias

Publikováno v: American Journal of Applied Sciences. 16:143-161

MDA-MB231 is a very aggressive and invasive triple negative breast cancer, which present with limited treatment options. Unlike other breast cancer types, it is characterized by absence of hormonal receptors of estrogen, progesterone as well as human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::444c463092743730824d39388ae8aef5
https://doi.org/10.3844/ajassp.2019.143.161

Far-field diffraction patterns and optical limiting properties of bisdemethoxycurcumin solution under CW laser illumination

Autor: Chassib A. Emshary, Qusay M.A. Hassan, Rita S. Elias, Bahjat A. Saeed, Ahmed S. Al-Asadi, H. Bakr, H.A. Sultan

Publikováno v: Optical Materials. 85:500-509

In this work, nonlinear optical properties of bisdemethoxycurcumin solution were studied using diffraction ring patterns method. Multiple diffraction rings observed as a continuous wave (CW) laser beam passes through a bisdemethoxycurcumin solution.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::83ad16ed8877f68a795c2861741a09bc
https://doi.org/10.1016/j.optmat.2018.09.021