Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rita Robin Wo"'
Autor:
Yu-Yun Shao, Min-Shu Hsieh, Yi-Hsuan Lee, Hung-Wei Hsu, Rita Robin Wo, Han-Yu Wang, Ann-Lii Cheng, Chih-Hung Hsu
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34289- (2024)
The anti-programmed death-ligand 1 (PD-L1) antibody is a standard therapy for advanced hepatocellular carcinoma (HCC). Tumor expression of PD-L1 can be induced upon stimulus. Because cyclin-dependent kinase 9 (CDK9) inhibition reduces the expression
Externí odkaz:
https://doaj.org/article/17d5b1d346e04280aa47dacdb32645f5
Publikováno v:
Oncology. 100(11)
Purpose: Composite cyclin-dependent kinase (CDK) inhibition has shown potential as a treatment for hepatocellular carcinoma (HCC) in preclinical studies. We tested whether the specific inhibition of CDK9 was effective against HCC. Methods: The effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3a68691a3038655c87cfa55a0fe8fa
https://pubmed.ncbi.nlm.nih.gov/36103810
https://pubmed.ncbi.nlm.nih.gov/36103810
Publikováno v:
Journal of Clinical Oncology. 40:425-425
425 Background: Composite cyclin dependent kinase (CDK) inhibition has shown potential as a treatment for hepatocellular carcinoma (HCC) in preclinical studies. We tested whether the specific inhibition of CDK9 was effective against HCC. Methods: The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21c61a8579468cc354d5d91a881ee2ce
https://doi.org/10.1200/jco.2022.40.4_suppl.425
https://doi.org/10.1200/jco.2022.40.4_suppl.425
Autor:
Han-Yu Wang, Chih-Hung Hsu, Hang Lin, Ann-Lii Cheng, Yong-Shi Li, Hung-Wei Hsu, Yu-Yun Shao, Rita Robin Wo
Publikováno v:
Cancers
Cancers, Vol 11, Iss 10, p 1433 (2019)
Cancers; Volume 11; Issue 10; Pages: 1433
Cancers, Vol 11, Iss 10, p 1433 (2019)
Cancers; Volume 11; Issue 10; Pages: 1433
Alterations in cell cycle regulators are common in hepatocellular carcinoma (HCC). We tested the efficacy of composite inhibition of CDKs 1, 2, 5, and 9 through dinaciclib on HCC. In vitro, dinaciclib exhibited potent antiproliferative activities in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002234c886e526dfed1030d3557937ca
https://pubmed.ncbi.nlm.nih.gov/31561409
https://pubmed.ncbi.nlm.nih.gov/31561409