Effects of half-dose spiomet treatment in girls with early puberty and accelerated bone maturation: a multicenter, randomized, placebo-controlled study protocol

Autor: Judit Bassols, Francis de Zegher, Marta Diaz, Gemma Carreras-Badosa, Cristina Garcia-Beltran, Elsa Puerto-Carranza, Cora Oliver-Vila, Paula Casano, Céline Alicia Franco, Rita Malpique, Abel López-Bermejo, Lourdes Ibáñez

Publikováno v: Trials, Vol 24, Iss 1, Pp 1-15 (2023)

Abstract Background A “mismatch” sequence of less prenatal weight gain and more postnatal weight gain may lead to ectopic lipid accumulation, and trigger the development of early adrenarche/pubarche and the activation of the gonadotropic axis res

Externí odkaz: https://doaj.org/article/7ef33d5fe3e340859d4fce4123e35594

Reduced circulating levels of chemokine CXCL14 in adolescent girls with polycystic ovary syndrome: normalization after insulin sensitization

Autor: Cristina García-Beltran, Ruben Cereijo, Tania Quesada-López, Rita Malpique, Abel López-Bermejo, Francis de Zegher, Lourdes Ibáñez, Francesc Villarroya

Publikováno v: BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)

ObjectiveCXCL14 (C-X-C motif chemokine ligand-14) is a chemokine released by active brown fat, showing protective effects against insulin resistance in experimental models. Polycystic ovary syndrome (PCOS) in adolescent girls is usually related to he

Externí odkaz: https://doaj.org/article/d887ba65e8a04c558add11addda27b6b

Posterior Cervical Brown Fat and CXCL14 Levels in the First Year of Life: Sex Differences and Association With Adiposity

Autor: Rubén Cereijo, Cristina Plou, Francis de Zegher, Joan Villarroya, Francesc Villarroya, Aleix Gavaldà-Navarro, Cristina Garcia-Beltran, Abel López-Bermejo, Lourdes Ibáñez, Rita Malpique

Publikováno v: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu

Context Brown adipose tissue (BAT) is particularly abundant in neonates, but its association with measures of adiposity and metabolic health in early infancy is poorly delineated. Besides sustaining nonshivering thermogenesis, BAT secretes brown adip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67fed5c61ffdb441186ed5ff5adbf98
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8136

microRNAs in newborns with low birth weight: relation to birth size and body composition

Autor: Abel López-Bermejo, Cristina Plou, Rita Malpique, Judit Bassols, Lourdes Ibáñez, Gemma Carreras-Badosa, Francis de Zegher, Cristina Garcia-Beltran

Publikováno v: Pediatric research. 92(3)

Background Children with low birth weight (LBW) have a higher risk of developing endocrine-metabolic disorders later in life. Deregulation of specific microRNAs (miRNAs) could underscore the programming of adult pathologies. We analyzed the miRNA exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4807653c9dfb1d4b7b55b0f48956329a
https://pubmed.ncbi.nlm.nih.gov/34799665

Toward a Treatment Normalizing Ovulation Rate in Adolescent Girls With Polycystic Ovary Syndrome

Autor: Abel López-Bermejo, Cristina Garcia-Beltran, Edurne Garde, Marta Díaz, Rita Malpique, Lourdes Ibáñez, Francis de Zegher

Publikováno v: Journal of the Endocrine Society

Adolescent polycystic ovary syndrome (PCOS) is characterized by androgen excess and oligomenorrhea, and commonly driven by hepato-visceral fat excess (“central obesity”) ensuing from a mismatch between prenatal and postnatal nutrition, on a backg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd95fef224d27ba16883b874d553cac
http://europepmc.org/articles/PMC7182125