Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Rita Maccarone"'
Autor:
Maddalena Sbaffone, Marie-Lise Jaffrain-Rea, Lucia Cappabianca, Francesca Carbonara, Francesca Gianno, Tiziana Feola, Marianna Ruggieri, Veronica Zelli, Rita Maccarone, Stefano Guadagni, Marco Clementi, Antonietta Arcella, Vincenzo Esposito, Giulia Carozza, Ilaria Martelli, Antonietta Rosella Farina, Andrew Reay Mackay
Publikováno v:
Biology, Vol 13, Iss 3, p 171 (2024)
Pituitary neuroendocrine tumors (PitNETs) are generally benign but comprise an aggressive, invasive, therapy-resistant, metastatic subset, underpinning a need for novel therapeutic targets. PitNETs exhibit low mutation rates but are associated with c
Externí odkaz:
https://doaj.org/article/16394a057224452daab107042774ee82
Autor:
Lucia Buccarello, Jessica Dragotto, Kambiz Hassanzadeh, Rita Maccarone, Massimo Corbo, Marco Feligioni
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Retinal ganglion cell (RGC) loss is a pathologic feature common to several retinopathies associated to optic nerve damage, leading to visual loss and blindness. Although several scientific efforts have been spent to understand the molecular
Externí odkaz:
https://doaj.org/article/6c767c267c3a4a3fbf72a220ff2f96e7
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6749 (2023)
Resolvin E1 (RvE1) is an eicosapentaenoic acid-derived lipid mediator involved in the resolution of inflammation. Here, we investigated whether RvE1 alterations may occur in an animal model of age-related macular degeneration (AMD). To this end, Spra
Externí odkaz:
https://doaj.org/article/89df0284fe434c23b2c7cbfde4b132c3
Autor:
Lucia Cappabianca, Veronica Zelli, Cristina Pellegrini, Michela Sebastiano, Rita Maccarone, Marco Clementi, Alessandro Chiominto, Pierdomenico Ruggeri, Ludovica Cardelli, Marianna Ruggieri, Maddalena Sbaffone, Maria-Concetta Fargnoli, Stefano Guadagni, Antonietta R. Farina, Andrew R. Mackay
Publikováno v:
Cells, Vol 12, Iss 2, p 237 (2023)
Post-therapeutic relapse, poor survival rates and increasing incidence justify the search for novel therapeutic targets and strategies in cutaneous malignant melanoma (CMM). Within this context, a potential oncogenic role for TrkA in CMM is suggested
Externí odkaz:
https://doaj.org/article/62c5e9768b1b44a98ca1d5788ab7098f
Autor:
Lucia Cappabianca, Stefano Guadagni, Rita Maccarone, Michela Sebastiano, Alessandro Chiominto, Antonietta Rosella Farina, Andrew Reay Mackay
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background Merkel cell carcinomas (MCCs) are rare, aggressive, therapeutically-challenging skin tumours that are increasing in incidence and have poor survival rates. The majority are caused by genomic Merkel cell polyomavirus (MCPyV) integr
Externí odkaz:
https://doaj.org/article/040063e8b1a04d00a41c70d4bb99b215
Autor:
Giulia Carozza, Annamaria Tisi, Annamaria Capozzo, Benedetta Cinque, Aldo Giovannelli, Marco Feligioni, Vincenzo Flati, Rita Maccarone
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14771 (2022)
Opposing dose-dependent effects of curcumin (Cur) have been documented in Retinal Pigment Epithelium (RPE); therefore, to shed the light on the mechanisms of action is crucial for ophthalmic applications. On this basis we explored new insights about
Externí odkaz:
https://doaj.org/article/63abdfe86b10469e9eceecdeb2c271d2
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2935 (2022)
The mammalian target of rapamycin (mTOR) signaling plays a critical role in cell homeostasis, growth and survival. Here, we investigated the localization of the main mTOR signaling proteins in the organ of Corti of normal-hearing and deafened guinea
Externí odkaz:
https://doaj.org/article/4b7515fb4af9464c80f26ce0ca590b81
Autor:
Annamaria Tisi, Fanny Pulcini, Giulia Carozza, Vincenzo Mattei, Vincenzo Flati, Maurizio Passacantando, Cinzia Antognelli, Rita Maccarone, Simona Delle Monache
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1133 (2022)
In this study, we investigated whether cerium oxide nanoparticles (CeO2-NPs), a promising antioxidant nanomaterial, may contrast retinal vascular alterations induced by oxidative damage in vitro and in vivo. For the in vivo experiments, the light dam
Externí odkaz:
https://doaj.org/article/13119376de6946f1a10f4367d679561a
Publikováno v:
Brain Sciences, Vol 12, Iss 1, p 2 (2021)
We investigated whether treatment with brain-derived neurotrophic factor (BDNF), which is known to protect spiral ganglion cells (SGCs), could also protect hair cells (HCs) and supporting cells (SCs) in the organ of Corti of a guinea pig model of sen
Externí odkaz:
https://doaj.org/article/ef2898fe3b2240029ccf439e03c4c8f8
Publikováno v:
Cells, Vol 10, Iss 1, p 64 (2021)
The blood retinal barrier (BRB) is a fundamental eye component, whose function is to select the flow of molecules from the blood to the retina and vice-versa, and its integrity allows the maintenance of a finely regulated microenvironment. The outer
Externí odkaz:
https://doaj.org/article/5c28a85c31794dbdb7ea5f3c000f7d2c