Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Rita M Meganck"'
Autor:
Rita M Meganck, Deanna Zhu, Stephanie Dong, Lisa J Snoderly-Foster, Yago R Dalben, Devina Thiono, Laura J White, Arivianda M DeSilva, Ralph S Baric, Longping V Tse
Publikováno v:
eLife, Vol 12 (2023)
A hallmark of dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://doaj.org/article/052e2b8492e2439d954641c9e43adbfa
Autor:
Victoria J Madigan, Julianne A Yuziuk, Anna M Chiarella, Tyne O Tyson, Rita M Meganck, Zachary C Elmore, Longping V Tse, Nathaniel A Hathaway, Aravind Asokan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007988 (2019)
Adeno-associated viruses (AAV) are Dependoparvoviruses that have shown promise as recombinant vectors for gene therapy. While infectious pathways of AAV are well studied, gaps remain in our understanding of host factors affecting vector genome expres
Externí odkaz:
https://doaj.org/article/fc7fbedd06ca440da188d4b61628143e
Autor:
Rita M. Meganck, Erin K. Borchardt, Ruth M. Castellanos Rivera, Miranda L. Scalabrino, Jeremy E. Wilusz, William F. Marzluff, Aravind Asokan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 89-98 (2018)
Circular RNAs (circRNAs) are long-lived, covalently closed RNAs that are abundantly expressed and evolutionarily conserved across eukaryotes. Possible functions ranging from microRNA (miRNA) and RNA binding protein sponges to regulators of transcript
Externí odkaz:
https://doaj.org/article/4b05f58b76984d22b571558cdd5de463
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Emerging coronaviruses (CoV) are constant global public health threats to society. Multiple ongoing clinical trials for vaccines and antivirals against CoVs showcase the availability of medical interventions to both prevent and treat the future emerg
Externí odkaz:
https://doaj.org/article/fb10e439aeef47708bec3eaead6dddc7
Autor:
Rita M. Meganck, Deanna Zhu, Stephanie Dong, Lisa J. Snoderly-Foster, Yago R. Dalben, Devina Thiono, Laura J. White, Aravinda M. DeSilva, Ralph S. Baric, Longping V. Tse
Publikováno v:
bioRxiv
A hallmark of Dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ed5d83705e9b49ba9f8de7f86938f1
https://europepmc.org/articles/PMC10081285/
https://europepmc.org/articles/PMC10081285/
Autor:
Ellen Young, Boyd Yount, Petraleigh Pantoja, Sandra Henein, Rita M. Meganck, Jennifer McBride, Jennifer E. Munt, Thomas J. Baric, Deanna Zhu, Trevor Scobey, Stephanie Dong, Longping V. Tse, Melween I. Martinez, Armando G. Burgos, Rachel L. Graham, Laura White, Aravinda DeSilva, Carlos A. Sariol, Ralph S. Baric
Publikováno v:
Nature Communications. 14
The four dengue virus serotypes co-circulate globally and cause significant human disease. Dengue vaccine development is challenging because some virus-specific antibodies are protective, while others are implicated in enhanced viral replication and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919cc5c043cb21730d1cfff55e3f2863
https://doi.org/10.1038/s41467-023-36702-x
https://doi.org/10.1038/s41467-023-36702-x
Autor:
Longping V. Tse, Rita M. Meganck, Stephanie Dong, Lily E. Adams, Laura J. White, Michael L. Mallory, Ramesh Jadi, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio. 13
Mature DENVs represent the dominant form in vivo and are the target for vaccine development. Here, we used multiple strategies, including protein engineering and natural and directed evolution to generate DENV1, -2, -3, and -4 variants that are highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a4532c9ae65fcd891fd222da15c327
https://doi.org/10.1128/mbio.00386-22
https://doi.org/10.1128/mbio.00386-22
Publikováno v:
RNA (New York, N.Y.). 28(11)
Metazoan histone mRNAs are the only cellular eukaryotic mRNAs that are not polyadenylated, ending instead in a conserved stem–loop. SLBP is bound to the 3′ end of histone mRNAs and is required for translation of histone mRNA. The expression of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e13befc2a3eb5be6199f36906a4c8d9
https://pubmed.ncbi.nlm.nih.gov/36041871
https://pubmed.ncbi.nlm.nih.gov/36041871
Autor:
Andrew E. Hale, Katherine E. Simon, William F. Marzluff, Rita M. Meganck, Jeremy E. Wilusz, Jiacheng Liu, Nathaniel J. Moorman, Aravind Asokan, Heather A. Vincent, Marco M. Fanous
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 821-834 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Circular RNAs (circRNAs) are highly stable RNA molecules that are attractive templates for expression of therapeutic proteins and non-coding RNAs. In eukaryotes, circRNAs are primarily generated by the spliceosome through backsplicing. Here, we inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d39cea54c678256b7578d7a49d26b5f
http://www.sciencedirect.com/science/article/pii/S2162253121000032
http://www.sciencedirect.com/science/article/pii/S2162253121000032
Autor:
Rita M. Meganck, Ralph S. Baric
Publikováno v:
Nature Medicine. 27:401-410
The twenty-first century has already recorded more than ten major epidemic or pandemic virus emergence events, including the ongoing and devastating coronavirus disease 2019 (COVID-19) pandemic. As viral disease emergence is expected to accelerate, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd66fcaa41ab71b91c01afcaab610979
https://doi.org/10.1038/s41591-021-01282-0
https://doi.org/10.1038/s41591-021-01282-0