Výsledky vyhledávání - "Rita K. Bowers"

A clinical flow cytometric biomarker strategy: validation of peripheral leukocyte phospholipidosis using Nile red

Autor: David Monteith, Bartley W. Halstead, Brian R. Berridge, Craig E. Thomas, Ryan E. Morgan, Rita K. Bowers, Craig Zwickl

Publikováno v: Journal of Applied Toxicology. 26:169-177

Phospholipidosis, or intracellular accumulation of phospholipids, is caused by specific classes of xenobiotics. This phenomenon represents a challenge for risk assessment that could benefit from the use of biomarkers in the clinical development of ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eac9b6a7053f671470fbb36611bb773
https://doi.org/10.1002/jat.1120

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A platelet biomarker for assessing phosphoinositide 3-kinase inhibition during cancer chemotherapy

Autor: Andrew L. Faber, Philip Marder, James E. Thomas, Rita K. Bowers, Candice Horn, Lisa J. Green

Publikováno v: Molecular cancer therapeutics. 6(9)

Thrombin cleavages of selective proteinase-activated receptors (PAR) as well as PAR-activating peptide ligands can initiate the phosphoinositide 3-kinase (PI3K) signaling cascade in platelets. Downstream to this event, fibrinogen receptors on platele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115f61ab7bd84edc26a4cfb8b1aedfef
https://pubmed.ncbi.nlm.nih.gov/17766838

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