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of 19
pro vyhledávání: '"Rita Gemayel"'
Variable repeats in the eukaryotic polyubiquitin gene ubi4 modulate proteostasis and stress survival
Autor:
Rita Gemayel, Yudi Yang, Maria C. Dzialo, Jacek Kominek, Jakob Vowinckel, Veerle Saels, Leen Van Huffel, Elisa van der Zande, Markus Ralser, Jan Steensels, Karin Voordeckers, Kevin J. Verstrepen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Eukaryotic cells rely on the ubiquitin-proteasome system for selective degradation of proteins, a process vital to organismal fitness. Here the authors show that the number of repeats in the polyubiquitin gene is evolutionarily unstable within and be
Externí odkaz:
https://doaj.org/article/e68fdad09bea48b29b4e7d92488ae766
Autor:
Rita Gemayel, Seamus J. Martin
Publikováno v:
The FEBS Journal. 286:39-45
Giving effective and interesting talks are key skills for scientists at every stage of their career. This installment of the Words of Advice series provides some insights into preparing and delivering compelling presentations, as well as alleviating
Autor:
Rita Gemayel
Publikováno v:
The FEBS Journal. 285:1180-1184
Poster sessions are an important forum for getting feedback on your results and engaging with the scientific community. In this instalment of the Words of Advice series, we provide you with a guide to designing an outstanding poster and offer tips on
Autor:
Rita Gemayel, Seamus J. Martin
Publikováno v:
The FEBS Journal. 284:3771-3777
Writing a competitive grant application is an essential skill for any scientist who wants to embark on an independent career. This instalment of the Words of Advice series provides a comprehensive guide to preparing a successful grant or personal fel
Autor:
Rita, Gemayel
Publikováno v:
The FEBS Journal. 284:2700-2704
In the second part of our Words of Advice on science careers, we bring you the perspectives of established scientists who enjoy successful, fulfilling careers in academia, the patent office and a publishing company. We also get the thoughts of a PhD
Autor:
Ksenia Pougach, Joost Schymkowitz, Elisa van der Zande, Kris Gevaert, Sreenivas Chavali, M. Madan Babu, Kevin J. Verstrepen, Matthieu Legendre, Bo Zhu, Frederic Rousseau, Rita Gemayel, Steven Boeynaems
Publikováno v:
Molecular Cell
MOLECULAR CELL
MOLECULAR CELL
Summary Excessive expansions of glutamine (Q)-rich repeats in various human proteins are known to result in severe neurodegenerative disorders such as Huntington’s disease and several ataxias. However, the physiological role of these repeats and th
Autor:
Rita Gemayel
Publikováno v:
The FEBS journal. 284(16)
Understanding the dynamic behaviour of the Plasmodium falciparum metabolism during infection can help identify targets for drug development. In this Commentary, we highlight recently published studies in The FEBS Journal that cover mathematical model
Autor:
Elizabeth Ing-Simmons, Guilhem Chalancon, S. Balaji, M. Madan Babu, Natasha S. Latysheva, Rita Gemayel, Sreenivas Chavali, Kevin J. Verstrepen, Pavithra L. Chavali, Natalia Sanchez de Groot
Proteins with amino acid homorepeats have the potential to be detrimental to cells and are often associated with human diseases. Why, then, are homorepeats prevalent in eukaryotic proteomes? In yeast, homorepeats are enriched in proteins that are ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae7758c4dcbdf77652171b0a238828c
https://europepmc.org/articles/PMC5603276/
https://europepmc.org/articles/PMC5603276/
Publikováno v:
The FEBS journal. 284(9)
Accurate and clear representation of scientific data is essential for the advancement of science. In this instalment of the Words of Advice series, we feature guidelines and tips on best practices for writing manuscripts, designing experiments and pr
Autor:
Rita Gemayel, Emily J. Chenette
Publikováno v:
The FEBS journal. 283(15)
Bioengineering hair follicles using cells isolated from human tissue remains as a difficult task. Dermal papilla (DP) cells are known to guide the growth and cycling activities of hair follicles by interacting with keratinocytes. However, DP cells qu