Maternal γδ T cells shape offspring pulmonary type 2 immunity in a microbiota-dependent manner

Autor: Pedro H. Papotto, Bahtiyar Yilmaz, Gonçalo Pimenta, Sofia Mensurado, Carolina Cunha, Gina J. Fiala, Daniel Gomes da Costa, Natacha Gonçalves-Sousa, Brian H.K. Chan, Birte Blankenhaus, Rita G. Domingues, Tânia Carvalho, Matthew R. Hepworth, Andrew J. Macpherson, Judith E. Allen, Bruno Silva-Santos

Publikováno v: Papotto, Pedro H; Yilmaz, Bahtiyar; Pimenta, Gonçalo; Mensurado, Sofia; Cunha, Carolina; Fiala, Gina J; Gomes da Costa, Daniel; Gonçalves-Sousa, Natacha; Chan, Brian H K; Blankenhaus, Birte; Domingues, Rita G; Carvalho, Tânia; Hepworth, Matthew R; Macpherson, Andrew J; Allen, Judith E; Silva-Santos, Bruno (2023). Maternal γδ T cells shape offspring pulmonary type 2 immunity in a microbiota-dependent manner. (In Press). Cell reports(112074), p. 112074. Cell Press 10.1016/j.celrep.2023.112074

Immune development is profoundly influenced by vertically transferred cues. However, little is known about how maternal innate-like lymphocytes regulate offspring immunity. Here, we show that mice born from γδ T cell-deficient (TCRδ-/-) dams displ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb309f2e5b0b74e2cec3d13af01851a9
https://boris.unibe.ch/178823/1/1-s2.0-S2211124723000852-main.pdf

NFIL3 Orchestrates the Emergence of Common Helper Innate Lymphoid Cell Precursors

Autor: Wei Xu, Rita G. Domingues, Diogo Fonseca-Pereira, Manuela Ferreira, Hélder Ribeiro, Silvia Lopez-Lastra, Yasutaka Motomura, Lara Moreira-Santos, Franck Bihl, Véronique Braud, Barbara Kee, Hugh Brady, Mark C. Coles, Christian Vosshenrich, Masato Kubo, James P. Di Santo, Henrique Veiga-Fernandes

Publikováno v: Cell Reports, Vol 10, Iss 12, Pp 2043-2054 (2015)

Innate lymphoid cells (ILCs) are a family of effectors that originate from a common innate lymphoid cell progenitor. However, the transcriptional program that sets the identity of the ILC lineage remains elusive. Here, we show that NFIL3 is a critica

Externí odkaz: https://doaj.org/article/456c7def4c7245ad98f0fe1a31ba12f1

Author Correction: Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization

Autor: Johannes U. Mayer, Kerry L. Hilligan, Jodie S. Chandler, David A. Eccles, Samuel I. Old, Rita G. Domingues, Jianping Yang, Greta R. Webb, Luis Munoz-Erazo, Evelyn J. Hyde, Kirsty A. Wakelin, Shiau-Choot Tang, Sally C. Chappell, Sventja von Daake, Frank Brombacher, Charles R. Mackay, Alan Sher, Roxane Tussiwand, Lisa M. Connor, David Gallego-Ortega, Dragana Jankovic, Graham Le Gros, Matthew R. Hepworth, Olivier Lamiable, Franca Ronchese

In the version of this article initially published, there were labeling errors in Fig. 8. In Fig. 8a, the top row, now reading “GSE43184:CD1c+ lung versus blood,” originally appeared as “GSE35457….” The bottom row, now reading “GSE35457:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff24999b9482f93856ec7fdd01b8fcba
https://hdl.handle.net/10453/167364

Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T

Autor: Johannes U, Mayer, Kerry L, Hilligan, Jodie S, Chandler, David A, Eccles, Samuel I, Old, Rita G, Domingues, Jianping, Yang, Greta R, Webb, Luis, Munoz-Erazo, Evelyn J, Hyde, Kirsty A, Wakelin, Shiau-Choot, Tang, Sally C, Chappell, Sventja, von Daake, Frank, Brombacher, Charles R, Mackay, Alan, Sher, Roxane, Tussiwand, Lisa M, Connor, David, Gallego-Ortega, Dragana, Jankovic, Graham, Le Gros, Matthew R, Hepworth, Olivier, Lamiable, Franca, Ronchese

Publikováno v: Nature immunology. 22(12)

The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral environments remain mostly undefined. We show that differentiation of CD11b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bec83d8e0cf687b2c9b9e9e8cd77afef
https://pubmed.ncbi.nlm.nih.gov/35418649

Neuro-mesenchymal units control ILC2 and obesity via a brain–adipose circuit

Autor: Joaquim Alves da Silva, Roel G. J. Klein Wolterink, Ines Mahú, Hélder Ribeiro, Henrique Veiga-Fernandes, Christina Godinho-Silva, Filipa L. Cardoso, Rita G. Domingues, Ana Domingos

Copyright © 2021, The Author(s), under exclusive licence to Springer Nature Limited
Signals from sympathetic neurons and immune cells regulate adipocytes and thereby contribute to fat tissue biology. Interactions between the nervous and immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2ad639a1e96d8d1fb0b65e311deba2
https://hdl.handle.net/10451/49544