UV–vis and FTIR–ATR spectroscopic techniques to study the inclusion complexes of genistein with β-cyclodextrins

Autor: Rita Ficarra, M. Guardo, Rosanna Stancanelli, Vincenzo Crupi, Domenico Majolino, Valentina Venuti

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 44:110-117

The effect of beta-cyclodextrin (beta-CyD), (2-hydroxypropyl)-beta-cyclodextrin (HP-beta-CyD) and methyl-beta-cyclodextrin (Me-beta-CyD) complexation on the UV absorption of genistein (Gen) was studied in pure water. A phase solubility study was perf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68713d8696095a551ecc09e129b4c27
https://doi.org/10.1016/j.jpba.2007.01.054

The rutin/β-cyclodextrin interactions in fully aqueous solution: spectroscopic studies and biological assays

Autor: Stefania Catania, Valentina Villari, Paola Ficarra, Chiara Costa, Rosanna Stancanelli, D. Raneri, Rita Ficarra, Paola Donato, Silvana Tommasini, Calabrò Ml

Publikováno v: Journal of pharmaceutical and biomedical analysis
36 (2005): 1019–1027. doi:10.1016/j.jpba.2004.09.018
info:cnr-pdr/source/autori:M.L. Calabrò; S. Tommasini; P. Donato; R. Stancanelli; D. Raneri; S. Catania; C. Costa; V. Villari; P. Ficarra; R. Ficarra/titolo:The rutin%2Fbeta-cyclodextrin interactions in fully aqueous solution: spectroscopic studies and biological assays/doi:10.1016%2Fj.jpba.2004.09.018/rivista:Journal of pharmaceutical and biomedical analysis (Print)/anno:2005/pagina_da:1019/pagina_a:1027/intervallo_pagine:1019–1027/volume:36

In the present work the feasibility of β-cyclodextrin complexation was explored, as a tool for improving the aqueous solubility and antioxidant efficacy of rutin. By means of 1 H NMR, UV–vis and circular dichroism spectroscopy the single aromatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75400be09371afd92a8b060f2fe6428
https://doi.org/10.1016/j.jpba.2004.09.018

Validation of a LC method for the analysis of oxaliplatin in a pharmaceutical formulation using an experimental design

Autor: S. Melardi, Paola Ficarra, Silvana Tommasini, Rita Ficarra, Mohammad H. Semreen, Giuseppe Altavilla, Paola Maria Cutroneo, Calabrò Ml, Sandra Furlanetto

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 29:1097-1103

A rapid and sensitive RP-HPLC method with UV detection for routine control of oxaliplatin in a pharmaceutical formulation (Eloxatin®) was developed. Quantitation was accomplished with the internal standard method. The procedure was validated by line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05726a5c014d165be6d3dae09ffc209
https://doi.org/10.1016/s0731-7085(02)00151-6

Diastereo-enantioseparation of novel γ-lactamic derivatives on cellulose chiral stationary phases

Autor: Paola Ficarra, S. Alcaro, Silvana Tommasini, Rita Ficarra, S. Melardi, M. L. Calabrò

Publikováno v: Scopus-Elsevier

This paper describes the enantiorecognition of 1-methyl-3-hydroxy-5-aryl-2-pyrrolidinonic systems by high-performance liquid chromatography using two chiral derivatized cellulose stationary phases (CSPs) operated in the normal phase mode. According o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622e12c0a2f2f7300834cdb8b785b5cf
https://doi.org/10.1007/bf02490477

Direct Enantiomeric Separation of Flavanones by High Performance Liquid Chromatography using Various Chiral Stationary Phases

Autor: Domenica Costantino, Silvana Tommasini, Carlo Bertucci, Paola Ficarra, Maria Carulli, Rita Ficarra, Calabrò Ml

Publikováno v: Planta Medica. 61:171-176

The performance of four chiral liquid chromatographic columns (Chiralcel OA, OJ, OC, OD) was studied with respect to the enantioseparation of flavanones and some derivatives. The effect of mobile phase composition on the retention time and stereo-sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9599c8facd42b7e96173e93ce74059f1
https://doi.org/10.1055/s-2006-958041