Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Rita De Gasperi"'
Autor:
Carlos A. Toro, Rita De Gasperi, Abdurrahman Aslan, Nicholas Johnson, Mustafa M. Siddiq, Christine Chow, Wei Zhao, Lauren Harlow, Zachary Graham, Xin-Hua Liu, Junichi Sadoshima, Ravi Iyengar, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 304-316 (2024)
Spinal cord injury (SCI) results in severe atrophy of skeletal muscle in paralyzed regions, and a decrease in the force generated by muscle per unit of cross-sectional area. Oxidation of skeletal muscle ryanodine 1 receptors (RyR1) reduces contractil
Externí odkaz:
https://doaj.org/article/c72386503aab4c5bbf2afb087a682fe8
Autor:
Rita De Gasperi, Laszlo Csernoch, Beatrix Dienes, Monika Gonczi, Jayanta K Chakrabarty, Shahar Goeta, Abdurrahman Aslan, Carlos A Toro, David Karasik, Lewis M Brown, Marco Brotto, Christopher P Cardozo
Publikováno v:
eLife, Vol 12 (2024)
Here, we investigated the mechanisms by which aging-related reductions of the levels of Numb in skeletal muscle fibers contribute to loss of muscle strength and power, two critical features of sarcopenia. Numb is an adaptor protein best known for its
Externí odkaz:
https://doaj.org/article/0f068916cd8b4549bdd0767378793140
Autor:
Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, Allison Sowa, Timothy Tetreault, Merina Varghese, David G. Cook, Carolyn W. Zhu, Susan J. Tappan, William G. M. Janssen, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract In the course of military operations in modern war theaters, blast exposures are associated with the development of a variety of mental health disorders associated with a post-traumatic stress disorder-related features, including anxiety, im
Externí odkaz:
https://doaj.org/article/0a667140f9af4965b012a6d8d6b76eae
Autor:
Georgina Perez Garcia, Gissel M. Perez, Rita De Gasperi, Miguel A. Gama Sosa, Alena Otero-Pagan, Rania Abutarboush, Usmah Kawoos, Jonathan K. Statz, Jacob Patterson, Carolyn W. Zhu, Patrick R. Hof, David G. Cook, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 197-217 (2023)
Many military veterans who experienced blast-related traumatic brain injuries (TBIs) in the conflicts in Iraq and Afghanistan suffer from chronic cognitive and mental health problems, including post-traumatic stress disorder (PTSD). Male rats subject
Externí odkaz:
https://doaj.org/article/a00017dd46604021950d704fc2ab811b
Autor:
Gregory A. Elder, Miguel A. Gama Sosa, Rita De Gasperi, Georgina Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Carolyn W. Zhu, William G. M. Janssen, James R. Stone, Patrick R. Hof, David G. Cook, Stephen T. Ahlers
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1150 (2024)
Blast-induced neurotrauma has received much attention over the past decade. Vascular injury occurs early following blast exposure. Indeed, in animal models that approximate human mild traumatic brain injury or subclinical blast exposure, vascular pat
Externí odkaz:
https://doaj.org/article/86098b3a3b9641eabe13317bfd33420e
Autor:
Rita De Gasperi, Chenglin Mo, Daniella Azulai, Zhiying Wang, Lauren M. Harlow, Yating Du, Zachary Graham, Jiangping Pan, Xin‐hua Liu, Lei Guo, Bin Zhang, Fred Ko, Ashleigh M. Raczkowski, William A. Bauman, Chris N. Goulbourne, Wei Zhao, Marco Brotto, Christopher P. Cardozo
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 454-466 (2022)
Abstract Background The role of Numb, a protein that is important for cell fate and development and that, in human muscle, is expressed at reduced levels with advanced age, was investigated; adult mice skeletal muscle and its localization and functio
Externí odkaz:
https://doaj.org/article/e3de719d0af0427d8b54e419b4474d11
Autor:
Georgina Perez Garcia, Gissel M. Perez, Alena Otero-Pagan, Rania Abutarboush, Usmah Kawoos, Rita De Gasperi, Miguel A. Gama Sosa, Dylan Pryor, Patrick R. Hof, David G. Cook, Sam Gandy, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 548-563 (2021)
Many military veterans who experienced blast-related traumatic brain injuries (TBIs) in the conflicts in Iraq and Afghanistan suffer from chronic cognitive and mental health problems, including post-traumatic stress disorder (PTSD). Transcranial lase
Externí odkaz:
https://doaj.org/article/7824eb3273a647d98a99a4c9d64a95be
Autor:
Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, William G. Janssen, Allison Sowa, Timothy Tetreault, David G. Cook, Susan J. Tappan, Sam Gandy, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-27 (2021)
Abstract Cerebral vascular injury as a consequence of blast-induced traumatic brain injury is primarily the result of blast wave-induced mechanical disruptions within the neurovascular unit. In rodent models of blast-induced traumatic brain injury, c
Externí odkaz:
https://doaj.org/article/ab5d8f1892bb40219c7b39ff4c4f768e
Autor:
Georgina Perez Garcia, Rita De Gasperi, Miguel A. Gama Sosa, Gissel M. Perez, Alena Otero-Pagan, Dylan Pryor, Rania Abutarboush, Usmah Kawoos, Patrick R. Hof, Dara L. Dickstein, David G. Cook, Sam Gandy, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-24 (2021)
Abstract Military veterans who experience blast-related traumatic brain injuries often suffer from chronic cognitive and neurobehavioral syndromes. Reports of abnormal tau processing following blast injury have raised concerns that some cases may hav
Externí odkaz:
https://doaj.org/article/0127541a2b2f4a099201801c41a05d43
Autor:
Ksenia Orekhova, Enna Selmanovic, Rita De Gasperi, Miguel A. Gama Sosa, Bridget Wicinski, Brigid Maloney, Alan Seifert, Akbar Alipour, Priti Balchandani, Tommaso Gerussi, Jean-Marie Graïc, Cinzia Centelleghe, Giovanni Di Guardo, Sandro Mazzariol, Patrick R. Hof
Publikováno v:
Veterinary Sciences, Vol 9, Iss 12, p 692 (2022)
The importance of assessing neurochemical processes in the cetacean brain as a tool for monitoring their cognitive health and to indirectly model human neurodegenerative conditions is increasingly evident, although available data are largely semiquan
Externí odkaz:
https://doaj.org/article/16ec44949d1e4697803ed47bfe448cb0