Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Rita Crinelli"'
Autor:
Tomas Di Mambro, Tania Vanzolini, Marzia Bianchi, Rita Crinelli, Barbara Canonico, Filippo Tasini, Michele Menotta, Mauro Magnani
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
The resistance and the birth of new intrinsic and multidrug-resistant pathogenic species like C. auris is creating great concern in the antifungal world. Given the limited drug arsenal and the lack of effectiveness of the available compounds, there i
Externí odkaz:
https://doaj.org/article/8a267b898848461ca8bffb6675f6ca8a
Autor:
Maria Gemma Nasoni, Serena Benedetti, Rita Crinelli, Francesco Palma, Barbara Canonico, Francesca Monittola, Chiara Zerbinati, Luigi Iuliano, Francesca Luchetti
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1148 (2022)
Oxysterols are a family of 27-carbon cholesterol oxidation derivatives found in low-density lipoproteins (LDLs) and atherosclerotic plaques where they trigger several biological responses involved in the initiation and progression of atherosclerosis.
Externí odkaz:
https://doaj.org/article/4f0d0291b3ee448681830c5bbe2ec50a
Publikováno v:
FEBS Open Bio, Vol 8, Iss 9, Pp 1471-1485 (2018)
The polyubiquitin gene ubiquitin C (UBC) is considered a stress protective gene and is upregulated under various stressful conditions, which is probably a consequence of an increased demand for ubiquitin in order to remove toxic misfolded proteins. W
Externí odkaz:
https://doaj.org/article/cfeae6dd2d354db09f532e16ca8c8a61
Autor:
Rita Crinelli, Carolina Zara, Luca Galluzzi, Gloria Buffi, Chiara Ceccarini, Michael Smietana, Michele Mari, Mauro Magnani, Alessandra Fraternale
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 175 (2021)
I-152 combines two pro-glutathione (GSH) molecules, namely N-acetyl-cysteine (NAC) and cysteamine (MEA), to improve their potency. The co-drug efficiently increases/replenishes GSH levels in vitro and in vivo; little is known about its mechanism of a
Externí odkaz:
https://doaj.org/article/4b3827904ea94069a23652894e33dc36
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136882 (2015)
The promoter of the polyubiquitin C gene (UBC) contains putative heat shock elements (HSEs) which are thought to mediate UBC induction upon stress. However, the mapping and the functional characterization of the cis-acting determinants for its up-reg
Externí odkaz:
https://doaj.org/article/c574d2cac7584302b97796d88d1bcab3
Autor:
Candida Vannini, Marcella Bracale, Rita Crinelli, Valerio Marconi, Paola Campomenosi, Milena Marsoni, Valeria Scoccianti
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108811 (2014)
Chemical inhibition of the proteasome has been previously found to effectively impair pollen germination and tube growth in vitro. However, the mediators of these effects at the molecular level are unknown. By performing 2DE proteomic analysis, 24 di
Externí odkaz:
https://doaj.org/article/2f859d6dc1984ed99ef5936f6b5cabc3
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65932 (2013)
In a number of organisms, introns affect expression of the gene in which they are contained. Our previous studies revealed that the 5'-UTR intron of human ubiquitin C (UbC) gene is responsible for the boost of reporter gene expression and is able to
Externí odkaz:
https://doaj.org/article/bcb635d497d040c5a4d285d32df5034d
Autor:
Alessandra Fraternale, Rita Crinelli, Anna Casabianca, Maria Filomena Paoletti, Chiara Orlandi, Elisa Carloni, Michaël Smietana, Anna Teresa Palamara, Mauro Magnani
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57866 (2013)
BACKGROUND: The aim of this study was to investigate the molecular mechanisms involved in the production of Th1 cytokines, namely IL-12 and IL-27, when the intra-macrophage redox state was altered by different chemical entities such as GSH-C4, which
Externí odkaz:
https://doaj.org/article/d219b79ec800468f85f8f31d61010fee
Autor:
Rita Crinelli, Elisa Carloni, Elisa Giacomini, Antonella Penna, Sabrina Dominici, Cecilia Battocchi, Patrizia Ciminiello, Carmela Dell'Aversano, Ernesto Fattorusso, Martino Forino, Luciana Tartaglione, Mauro Magnani
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38139 (2012)
Palytoxin and, likely, its analogues produced by the dinoflagellate genus Ostreopsis, represent a class of non-proteinaceous compounds displaying high toxicity in animals. Owing to the wide distribution and the poisonous effects of these toxins in hu
Externí odkaz:
https://doaj.org/article/c2f699a5eee3450299f45a1eed28b262
Autor:
Luca Galluzzi, Mauro De Santi, Rita Crinelli, Cinzia De Marco, Nadia Zaffaroni, Andrea Duranti, Giorgio Brandi, Mauro Magnani
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43249 (2012)
Indole-3-carbinol and its metabolic products are considered promising chemopreventive and anticancer agents. Previously we have shown that the indole-3-carbinol cyclic tetrameric derivative CTet induces autophagy and inhibits cell proliferation via i
Externí odkaz:
https://doaj.org/article/afd07769638f4b30aebe0cfd978e6e03